Results 121 to 130 of about 9,015,860 (307)

Modelling stem cell differentiation related processes—A practical overview for biologists

open access: yesFEBS Letters, EarlyView.
Stem cell differentiation is complex and difficult to control experimentally. This review introduces suitable computational modelling approaches that can support stem cell research, from mechanistic ODE and abstract models to multiscale and deep learning methods.
Ricco Zeegelaar   +4 more
wiley   +1 more source

Perspective functions with nonlinear scaling

open access: yesCommunications in Contemporary Mathematics
The classical perspective of a function is a construction which transforms a convex function into one that is jointly convex with respect to an auxiliary scaling variable. Motivated by applications in several areas of applied analysis, we investigate an extension of this construct in which the scaling variable is replaced by a nonlinear term.
Briceño-Arias, Luis M.   +2 more
openaire   +2 more sources

Design and analysis strategies for robust microbiome ageing research

open access: yesFEBS Letters, EarlyView.
The gut microbiome changes with age and associates with age‐related morbidity and mortality, establishing it as a potential biomarker and intervention target for ageing. Realising this potential requires methodological rigour, yet distinguishing biological signals from methodological artefacts remains challenging across cohorts. This review provides an
Mark Olenik   +5 more
wiley   +1 more source

ABL kinase‐dependent phosphorylation of SH proteins promotes their direct interaction with CRK family SH2 domains

open access: yesFEBS Letters, EarlyView.
CT10 regulator of kinase (CRK) and CRK‐Like (CRKL) are signaling adaptors driving cell adhesion, motility, differentiation, and proliferation. SH2‐domain containing (SH) proteins are enriched in YXXP motifs which when phosphorylated create preferred binding sites for CRK family SH2 domains.
Phoebe M. Cousens   +8 more
wiley   +1 more source

ON GENERALIGATIONS OF PARTITION FUNCTIONS

open access: yes, 2017
In 1742, Leonhard Euler invented the generating function for P(n). Godfrey Harold Hardy said Srinivasa Ramanujan was the first, and up to now the only, Mathematician to discover any such properties of P(n).
ON GENERALIGATIONS OF PARTITION FUNCTIONS   +1 more
core   +1 more source

Sensing the multi-scale landscape functions heterogeneity by big geodata from parcel to urban agglomerations-a case of the Greater Bay Area, China

open access: yesInternational Journal of Digital Earth
Multi-scale landscape functions play a critical role in revealing intricate functional structures within large regions. However, previous studies on landscape functions have predominantly focused on a single macro or micro scale, impeding a holistic ...
Ku Gao   +7 more
doaj   +1 more source

SCALE

open access: yes
<p>SCALE (Scalable Computing for Advanced Library and Environment) is a basic library for weather and climate model of the earth and planets aimed to be widely used in various models.
Matsushima, Toshiki   +10 more
core   +1 more source

Teaching functions through modeling [PDF]

open access: yes, 2013
textThis report discusses topics relating to modeling functions. The pedagogical content knowledge of student teachers and expert teachers and its effect on their ability to teach through modeling is examined. An observed modeling lesson is presented. To
Barlow, Brittany Kristine
core  

Limit Distributions and Scaling Functions [PDF]

open access: yes, 2009
We discuss the asymptotic behaviour of models of lattice polygons, mainly on the square lattice. In particular, we focus on limiting area laws in the uniform perimeter ensemble where, for fixed perimeter, each polygon of a given area occurs with the same probability. We relate limit distributions to the scaling behaviour of the associated perimeter and
openaire   +2 more sources

Scaling Functional Synthesis and Repair

open access: yes, 2019
Program synthesis was first proposed a few decades ago, but in the last decade it has gained increased momentum in the research community. The increasing complexity of software has dictated the urgent need for improved supporting tools that verify the software's correctness, and that automatically generate code from a formal contract provided by the ...
openaire   +2 more sources

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