Results 181 to 190 of about 705,866 (210)

Baseline Regional Cholinergic Denervation Predicts Cognitive Trajectories in Moderate Parkinson Disease

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Cognitive decline is a disabling and variable feature of Parkinson disease (PD). While cholinergic system degeneration is linked to cognitive impairments in PD, most prior research reported cross‐sectional associations. We aimed to fill this gap by investigating whether baseline regional cerebral vesicular acetylcholine transporter ...
Taylor Brown, Giulia Carli, Prabesh Kanel, Stiven Roytman, Jaimie Barr, Nicolaas I. Bohnen, Roger L. Albin   +6 more
wiley   +1 more source

Protocol to study direct (de)phosphorylation events on a proteome-wide scale using on-bead in vitro enzyme assays. [PDF]

STAR Protoc
Brunner M, Hu Z, Caligaris M, Stumpe M, De Virgilio C, Dengjel J.   +5 more
europepmc   +1 more source

Efficacy of Intermittent Theta‐Burst Stimulation for Prolonged Disorders of Consciousness: A Prospective, Randomized, Controlled Trial

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Background Emerging evidence suggests that low‐frequency neural oscillations are dynamically regulated by consciousness levels, with the recovery of low cortical activity potentially serving as a neurophysiological substrate for conscious emergence. Targeted enhancement of these low‐frequency rhythms in patients with disorders of consciousness
Chuan Xu, Jun Hu, Qianqian Wu, Min Wu, Yamei Yu, Hangcheng Li, Jian Gao, Jingqi Li, Nai Ding, Jie Yu, Benyan Luo   +10 more
wiley   +1 more source

Imaging Study of MnO₂-Based Nanomotors Modulating HIF-1α/Lipid Droplet Biogenesis and Activating the cGAS-STING Pathway. [PDF]

Biosensors (Basel)
Li Z, Tian Y, Ren G, Guo Y.
europepmc   +1 more source

Epilepsy‐Associated Variants of a Single SCN1A Codon Exhibit Divergent Functional Properties

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Pathogenic variants in SCN1A, which encodes the voltage‐gated sodium channel NaV1.1, are associated with multiple epilepsy syndromes exhibiting a range of clinical severity. SCN1A variants are reported in different syndromes, including Dravet syndrome, which is associated with loss‐of‐function, whereas neonatal/infantile‐onset ...
Lanie N. Liebovitz, Christopher H. Thompson, Linda C. Laux, Alfred L. George Jr.   +3 more
wiley   +1 more source

Immunosuppression in down syndrome regression disorder: a prospective observational cohort study. [PDF]

Brain Commun
Santoro JD, Kazerooni L, Lucas MC, Yousuf MM, Otey ST, Bouchard S, Frost KC, Nguyen L, Anadani NA, Mahmud A, Manning MA, Rachubinski AL, Kammeyer RM, Patel L, Koster LEA, van Eeghen AM, Spinazzi NA, Franklin C, Quinn EA, Espinosa JM, Rafii MS.   +20 more
europepmc   +1 more source

Inhibition of circZFX suppresses malignant phenotypes in cholangiocarcinoma via the miR-654-3p/HDGF and YAP1 signaling activation. [PDF]

Biol Direct
Liang T, Gong C, Yang X, Shen J, Jiang G, Liu J, Yang G, Guo L.   +7 more
europepmc   +1 more source

Quercetin ameliorates aflatoxin B₁-induced non-canonical ferroptosis in ovine oocytes through the OPA1/ACSL4 pathway. [PDF]

J Anim Sci Biotechnol
Li L, Liu B, Wang Z, Zhao R, Xiao X, Zhao Y, Qiu X.   +6 more
europepmc   +1 more source

The Effect of miR-129-5p on the Proliferation and Osteogenic Differentiation of Human Dental Pulp Stem Cells. [PDF]

Int Dent J
Yang F, Zhang Z, Qiu X, Lv H.
europepmc   +1 more source

Risk factors and nomogram prediction model for checkpoint inhibitor-related pneumonitis in patients with advanced non-small cell lung cancer. [PDF]

Front Med (Lausanne)
Chen YF, Tian J, Liu XM, Hu Y, He Y.
europepmc   +1 more source