Results 101 to 110 of about 15,333,409 (389)

Unraveling the metastasis‐preventing effect of miR‐200c in vitro and in vivo

Molecular Oncology, EarlyView.
Advanced tumors and ineffective cancer treatments can lead to metastases in distant organs. The sole expression of microRNA 200c (miR‐200c) in breast cancer cells is shown to significantly reduce metastasis formation in xenograft mouse models. Various in vitro analyses revealed impeded migratory behavior, upon miR‐200c expression, as one prerequisite ...
Bianca Köhler, Emily Brieger, Tom Brandstätter, Elisa Hörterer, Ulrich Wilk, Jana Pöhmerer, Anna Jötten, Philipp Paulitschke, Chase P. Broedersz, Stefan Zahler, Joachim O. Rädler, Ernst Wagner, Andreas Roidl   +12 more
wiley   +1 more source

Correcting batch effects in large-scale multiomics studies using a reference-material-based ratio method

Genome Biology, 2023
Background Batch effects are notoriously common technical variations in multiomics data and may result in misleading outcomes if uncorrected or over-corrected.
Ying Yu, Naixin Zhang, Yuanbang Mai, Luyao Ren, Qiaochu Chen, Zehui Cao, Qingwang Chen, Yaqing Liu, Wanwan Hou, Jingcheng Yang, Huixiao Hong, Joshua Xu, Weida Tong, Lianhua Dong, Leming Shi, Xiang Fang, Yuanting Zheng   +16 more
doaj   +1 more source

Disrupting the one-loop renormalization group invariant M/alpha in supersymmetry

, 1998
It is well known that in low energy supersymmetry the ratio of the gaugino mass to the gauge coupling squared, M/alpha, is renormalization group invariant to one-loop.
Alvarez-Gaume, Ambrosanio, Ambrosanio, Ambrosanio, Ambrosanio, Ambrosanio, Arkani-Hamed, Avdeev, Babu, Bagger, Barger, Barger, Binétruy, Brignole, Capper, Carena, Carena, Carone, Castaño, Chankowski, Cheng, Cohen, Cohen, Cremmer, Cvetič, Dasgupta, Davies, de Carlos, del Aguila, del Aguila, del Aguila, del Aguila, Dienes, Dienes, Dimopoulos, Dimopoulos, Dine, Dine, Dine, Drees, Drees, Dvali, Ellis, Ellis, Ellis, Farrar, Feng, Ferreira, Font, Ghilencea, Ghilencea, Graham D. Kribs, Haber, Hall, Hall, Hewett, Hikasa, Hikasa, Hill, Hisano, Hisano, Hisano, Holdom, Ibáñez, Ibáñez, Ibáñez, Ibáñez, Ibáñez, Inoue, Inoue, Jack, Jack, Jack, Kane, Kane, Kaplunovsky, Kawamura, Keith, King, Kolda, Langacker, Lopez, Martin, Martin, Martin, Martin, Mohapatra, Mohapatra, Nelson, Nilles, Nojiri, Nojiri, Novikov, Novikov, Novikov, Olechowski, Pierce, Pierce, Poppitz, Randall, Ring, Ross, Shafi, Shifman, Siegel, Yamada, Yamada, Yamada, Zhang, Zichichi   +109 more
core   +1 more source

The PREP pipeline: standardized preprocessing for large-scale EEG analysis

Front. Neuroinform., 2015
The technology to collect brain imaging and physiological measures has become portable and ubiquitous, opening the possibility of large-scale analysis of real-world human imaging. By its nature, such data is large and complex, making automated processing
Nima Bigdely Shamlo, T. Mullen, Christian Kothe, Kyungmin Su, K. Robbins   +4 more
semanticscholar   +1 more source

A novel length-based empirical estimation method of spawning potential ratio (SPR), and tests of its performance, for small-scale, data-poor fisheries

, 2015
The spawning potential ratio (SPR) is a well-established biological reference point, and estimates of SPR could be used to inform management decisions for data-poor fisheries. Simulations were used to investigate the utility of the length-based model (LB-
Adrian R. Hordyk, K. Ono, S. Valencia, N. Loneragan, J. Prince   +4 more
semanticscholar   +1 more source

Cellular liquid biopsy provides unique chances for disease monitoring, preclinical model generation and therapy adjustment in rare salivary gland cancer patients

Molecular Oncology, EarlyView.
We quantified and cultured circulating tumor cells (CTCs) of 62 patients with various cancer types and generated CTC‐derived tumoroid models from two salivary gland cancer patients. Cellular liquid biopsy‐derived information enabled molecular genetic assessment of systemic disease heterogeneity and functional testing for therapy selection in both ...
Nataša Stojanović Gužvić, Florian Lüke, Steffi Treitschke, Andrea Coluccio, Martin Hoffmann, Giancarlo Feliciello, Adithi Ravikumar Varadarajan, Xin Lu, Kathrin Weidele, Catherine Botteron, Silvia Materna–Reichelt, Felix Keil, Katja Evert, Florian Weber, Thomas Schamberger, Michael Althammer, Jirka Grosse, Dirk Hellwig, Christian Schulz, Stephan Seitz, Peter Ugocsai, Anke Schlenska‐Lange, Roman Mayr, Ulrich Kaiser, Wolfgang Dietmaier, Bernhard Polzer, Jens Warfsmann, Kamran Honarnejad, Tobias Pukrop, Daniel Heudobler, Christoph A. Klein, Christian Werno   +31 more
wiley   +1 more source

Asymptotic rigidity of scaling ratios for critical circle mappings [PDF]

arXiv, 1996
In this paper we establish $C^2$ a-priori bounds for the scaling ratios of critical circle mappings in a form that gives also a compactness property for the renormalization operator.
arxiv  

Combined spatially resolved metabolomics and spatial transcriptomics reveal the mechanism of RACK1‐mediated fatty acid synthesis

Molecular Oncology, EarlyView.
The authors analyzed the spatial distributions of gene and metabolite profiles in cervical cancer through spatial transcriptomic and spatially resolved metabolomic techniques. Pivotal genes and metabolites within these cases were then identified and validated.
Lixiu Xu, Jinqiu Li, Junqi Ma, Ayshamgul Hasim   +3 more
wiley   +1 more source

The Directions of Selection Bias [PDF]

arXiv, 2016
We show that if the exposure and the outcome affect the selection indicator in the same direction and have non-positive interaction on the risk difference, risk ratio or odds ratio scale, the exposure-outcome odds ratio in the selected population is a lower bound for true odds ratio.
arxiv  

Lepton flavor violating Higgs boson decays in seesaw models: new discussions

, 2017
The lepton flavor violating decay of the Standard Model-like Higgs boson (LFVHD), h->\mu\tau, is discussed in seesaw models at the one-loop level. Based on particular analytic expressions of Passarino-Veltman functions, the two unitary and 't Hooft ...
Hue, L. T., Hung, H. T., Thao, N. H., Xuan, N. T.   +3 more
core   +2 more sources