Results 101 to 110 of about 2,190,376 (310)
Hijacking emergency granulopoiesis: Neutrophil ontogeny and reprogramming in cancer
Molecular Oncology, EarlyView.Neutrophils are highly plastic innate immune cells; their functions in cancer extend beyond the tumour microenvironment. This Review summarises current understanding of neutrophil maturation and heterogeneity and highlights tumour‐induced granulopoiesis as a systemic programme that expands immature, immunosuppressive neutrophils via tumour‐derived ...
Gabriela Marinescu, Yi Feng
wiley +1 more source
A Musical Scale Generated from the Ratio of Consecutive Primes [PDF]
, 2015 This paper describes a 12-note musical scale generated from the ratio of consecutive prime numbers that is used as the basis for the author's electronic composition The Music of the Primes.
Reginald Bain
core
Molecular Oncology, EarlyView.Intratumour heterogeneity complicates precision management of advanced endometrial cancer. Circulating tumor DNA (ctDNA) offers a minimally invasive strategy to capture tumor evolution and therapeutic resistance. Here, we compare tumor‐agnostic NGS with tumor‐informed ddPCR, outlining their relative sensitivity, concordance, and clinical implications ...
Carlos Casas‐Arozamena +15 more
wiley +1 more source
Results of prevalence study regarding comorbilities for various patients [PDF]
Revista Română de Statistică, 2013 It is known that health problem represents an object of permanent study. The study to prevent chronic diseases, factors involved to keep the health status, means to improve the effect of various diseases/affections have been and are appreciated.
A. Capisizu +3 more
doaj
Frontiers in Aging Neuroscience, 2018 Background: Cerebrospinal fluid (CSF) biomarkers (Aβ peptides and tau proteins) improved the diagnosis of Alzheimer’s disease (AD) in research and clinical settings.
Sylvain Lehmann +16 more
doaj +1 more source
Mating ecology explains patterns of genome elimination [PDF]
, 2014 This research has been supported by a Royal Society University Research Fellowship (AG), a Royal Society Newton International Fellowship (LR) and two NERC Independent Research Fellowships (AG & LR).Genome elimination – whereby an individual discards ...
Ross, Laura, Gardner, Andy
core +1 more source
Molecular Oncology, EarlyView.Here, we demonstrate that HS1BP3 interacts with Cortactin through a proline‐rich region (PRR3.1) and show that this interaction, and HS1BP3 itself, promote cancer cell proliferation and invasion. Inhibition of this interaction leads to build‐up of TKS5 in multivesicular endosomes and altered secretion of CD63 and CD9, providing an explanation for the ...
Arja Arnesen Løchen +9 more
wiley +1 more source
Ratio scales of acid sourness [PDF]
Perception & Psychophysics, 1971 Experiments were conducted to assess the relation between concentration, or pH, and the perceived sourness of 24 acids. The psychophysical functions for sourness conform to the power relation S = kCn which relates sensory intensity, S, to physical concentration, C.
openaire +1 more source
Is Rising Returns to Scale a Figment of Poor Data? [PDF]
While using detailed firm-level data from the private business sector, this study identifies two empirical puzzles: (i) returns-to-scale (RTS) parameter estimates rise at higher levels of data aggregation, and (ii) estimates from the firm level suggest ...
Lindström, Tomas, Hansen, Sten
core
Molecular Oncology, EarlyView.This study shows that lung adenocarcinomas exploit developmental branching morphogenesis to acquire a therapy resistant basal‐like tumour cell state. This process was found to be regulated by combined TP53 loss‐of‐function and type‐I interferon signalling, identifying a novel axis for biomarker and therapeutic target discovery.
Kamila J Bienkowska +13 more
wiley +1 more source