Results 131 to 140 of about 5,426,024 (302)
Journal of Physics: Conference Series, 2014 We present a series of recent works related to group theoretical factors from GUT symmetry breaking which lead to predictions for the ratios of quark and lepton Yukawa couplings at the unification scale. New predictions for the GUT scale ratios yμ/ys, yτ/yb and yt/yb in particular are shown and compared to experimental data.
openaire +1 more source
Ratio-Scale Elicitation of Degrees of Support [PDF]
, 1993 During the last decade, the computational paradigms known as inflzcence diagrams and belief networks have become to dominate the diagnostic expert systems field.
Schocken, Shimon
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Molecular Oncology, EarlyView.Keratin 19 (KRT19) is overexpressed in high‐grade serous ovarian cancer with high levels of Kallikrein‐related peptidases (KLK) 4–7 and is associated with poor survival. In vivo analyses demonstrate that elevated KRT19 increases peritoneal tumour burden.
Sophia Bielesch +13 more
wiley +1 more source
Somatic mutational landscape in von Hippel–Lindau familial hemangioblastoma
Molecular Oncology, EarlyView.The causes of central nervous system (CNS) hemangioblastoma in Von Hippel–Lindau (vHL) disease are unclear. We used Whole Exome Sequencing (WES) on familial hemangioblastoma to investigate events that underlie tumor development. Our findings suggest that VHL loss creates a permissive environment for tumor formation, while additional alterations ...
Maja Dembic +5 more
wiley +1 more source
Molecular Oncology, EarlyView.We have established a humanized orthotopic patient‐derived xenograft (Hu‐oPDX) mouse model of high‐grade serous ovarian cancer (HGSOC) that recapitulates human tumor–immune interactions. Using combined anti‐PD‐L1/anti‐CD73 immunotherapy, we demonstrate the model's improved biological relevance and enhanced translational value for preclinical ...
Luka Tandaric +10 more
wiley +1 more source
Full-Scale Modeling and FBGs Experimental Measurements for Thermal Analysis of Converter Transformer
SensorsAs the imbalance between power demand and load capacity in electrical systems becomes increasingly severe, investigating the temperature variations in transformers under different load stresses is crucial for ensuring their safe operation.
Fan Yang +4 more
doaj +1 more source
E2A selectively regulates TGF‐β–induced apoptosis in KRAS‐mutant non‐small cell lung cancer
Molecular Oncology, EarlyView.Ability to induce apoptosis by TGF‐β is frequently lost in advanced lung adenocarcinoma despite intact TGF‐β signaling. We identify E2A as a mutant KRAS–dependent mediator of resistance to TGF‐β–induced apoptosis. TGF‐β induces E2A via SMAD3 in mutant KRAS cells, and E2A silencing restores apoptosis and enhances radiation response in cell lines ...
Sergei Chuikov +3 more
wiley +1 more source
Jurnal Anestesi PerioperatifMorfin sebagai analgetik pada laparotomi memiliki efek samping yang merugikan dan potensi menyebabkan kecanduan. Infus lidokain intravena (IVLI) merupakan alternatif analgetik perioperatif yang di nilai lebih aman dan efektif.
Adi Kurniawan +4 more
doaj +1 more source
KDM7A and KDM1A inhibition suppresses tumour promoting pathways in prostate cancer
Molecular Oncology, EarlyView.Treatment resistance is a major challenge for patients with advanced prostate cancer. This study examined an alternative approach to target the major prostate cancer‐promoting pathway by targeting epigenetic factors, whose levels are higher in tumours.
Jennie N Jeyapalan +16 more
wiley +1 more source
A CHARACTERIZATION OF HOMOGENEOUS PRODUCTION FUNCTIONS [PDF]
This paper states a theorem that characterizes homogeneous production functions in terms of the ratio of average to marginal costs. The theorem claims that a production function is homogeneous of degree k if and only if the ratio of average costs to ...
Hernán Vallejo, Pietro Bonaldi
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