Results 81 to 90 of about 15,576,713 (334)
Modeling hepatic fibrosis in TP53 knockout iPSC‐derived human liver organoids
Molecular Oncology, EarlyView.This study developed iPSC‐derived human liver organoids with TP53 gene knockout to model human liver fibrosis. These organoids showed elevated myofibroblast activation, early disease markers, and advanced fibrotic hallmarks. The use of profibrotic differentiation medium further amplified the fibrotic signature seen in the organoids.
Mustafa Karabicici +8 more
wiley +1 more source
Earth and Planetary PhysicsThe CUG_CLMFM3D series comprises high-resolution three-dimensional lithospheric magnetic field models for China and its surroundings. The first version, CUG_CLMFM3Dv1, is a spherical cap harmonic model integrating the WDMAMv2 (World Digital Magnetic ...
Pan Zhang +7 more
doaj +1 more source
Computing an Exact Gaussian Scale-Space
Image Processing On Line, 2016 Gaussian convolution is one of the most important algorithms in image processing. The present work focuses on the computation of the Gaussian scale-space, a family of increasingly blurred images, responsible, among other things, for the scale-invariance ...
Ives Rey Otero, Mauricio Delbracio
doaj +1 more source
Molecular Oncology, EarlyView.Adaptaquin selectively kills glioma stem cells while sparing differentiated brain cells. Transcriptomic and proteomic analyses show Adaptaquin disrupts iron and cholesterol homeostasis, with iron chelation amplifying cytotoxicity via cholesterol depletion, mitochondrial dysfunction, and elevated reactive oxygen species.
Adrien M. Vaquié +16 more
wiley +1 more source
A cubed-sphere based method for global and regional modeling of the lithospheric magnetic field
Earth and Planetary PhysicsThe Earth’s magnetic field, which has been extensively observed from ground to satellite altitudes over several decades, originates from multiple sources, such as the core dynamo, the conductive mantle, the magnetized lithosphere, and the space current ...
Liang Yin +5 more
doaj +1 more source
A network for multiscale image segmentation [PDF]
, 1988 Detecting edges of objects in their images is a basic problem in computational vision. The scale-space technique introduced by Witkin [11] provides means of using local and global reasoning in locating edges.
Malik, Jitendra, Perona, Pietro
core
Scale Anomalies, States, and Rates in Conformal Field Theory
, 2016 This paper presents two methods to compute scale anomaly coefficients in conformal field theories (CFTs), such as the c anomaly in four dimensions, in terms of the CFT data.
Gillioz, Marc +2 more
core +1 more source
Molecular Oncology, EarlyView.ERRFI1, a neural crest (NC)‐associated gene, was upregulated in melanoma and negatively correlated with the expression of melanocytic differentiation markers and the susceptibility of melanoma cells toward BRAF inhibitors (BRAFi). Knocking down ERRFI1 significantly increased the sensitivity of melanoma cells to BRAFi.
Nina Wang +8 more
wiley +1 more source
Earth and Planetary PhysicsThe equivalent source (ES) method in the spherical coordinate system has been widely applied to processing, reduction, field modeling, and geophysical and geological interpretation of satellite magnetic anomaly data.
JiangSong Gui +7 more
doaj +1 more source
Cybergeo, 2018 Starting from a practice of research that has been going back for years on the question of the use of scales in geohistorical works, this text offers a reflection on the plays of scale, as well as on the question of the MAUP (modifiable areal unit ...
Nicolas Verdier, Ludovic Chalonge
doaj +1 more source