Results 81 to 90 of about 1,188,974 (311)

CCDC80 suppresses high‐grade serous ovarian cancer migration via negative regulation of B7‐H3

open access: yesMolecular Oncology, EarlyView.
PAX8 is a lineage‐specific master regulator of transcription in high‐grade serous ovarian cancer (HGSC) progression. We show for the first time that PAX8 facilitates proliferation and metastasis by repressing the cell autonomous tumor suppressor CCDC80 and inducing B7‐H3 expression.
Aya Saleh   +12 more
wiley   +1 more source

An alternative regularization approach for modeling the regional lithospheric magnetic field from satellite magnetic measurements by the spherical equivalent source method and its application in Africa

open access: yesEarth and Planetary Physics
The equivalent source (ES) method in the spherical coordinate system has been widely applied to processing, reduction, field modeling, and geophysical and geological interpretation of satellite magnetic anomaly data.
JiangSong Gui   +7 more
doaj   +1 more source

Cell‐cycle‐specific lesion evolution rather than inhibition of double‐strand‐break repair underpins cisplatin radiosensitization

open access: yesMolecular Oncology, EarlyView.
We analyze cisplatin–DNA adducts (CDAs) and double‐strand breaks (DSBs) in a cell‐cycle‐dependent manner. We find that CDAs form similarly across all cell cycle phases. DSBs arise only in S‐phase. CDAs might not directly impair DSB repair, but S‐phase DSB lesions evolve in the presence of CDAs and disrupt repair in G2, also causing radiosensitization ...
Ye Qiu   +10 more
wiley   +1 more source

Morphological Semigroups and Scale-Spaces on Ultrametric Spaces [PDF]

open access: yes, 2017
Ultrametric spaces are the natural mathematical structure to deal with data embedded into a hierarchical representation. This kind of representations is ubiquitous in morphological image processing, from pyramids of nested partitions to more abstract dendrograms from minimum spanning trees.
Jesús Angulo, Santiago Velasco-Forero
openaire   +1 more source

Scale-covariant and scale-invariant Gaussian derivative networks

open access: yes, 2020
This article presents a hybrid approach between scale-space theory and deep learning, where a deep learning architecture is constructed by coupling parameterized scale-space operations in cascade.
Lindeberg, Tony   +2 more
core   +1 more source

Revised global vertically integrated remanent magnetization model of the oceanic lithosphere with comparison to LCS-1 model and MSS-1 magnetic measurements

open access: yesEarth and Planetary Physics
The lithospheric magnetic field is an important component of the geomagnetic field, and the oceanic lithosphere exhibits distinct characteristics. Because of its formation mechanisms, evolutionary history, and geomagnetic field polarity reversals, the ...
ShiDa Sun   +5 more
doaj   +1 more source

La question des échelles en géohistoire. Les bureaux de la poste aux lettres du XVIIIe siècle à nos jours

open access: yesCybergeo, 2018
Starting from a practice of research that has been going back for years on the question of the use of scales in geohistorical works, this text offers a reflection on the plays of scale, as well as on the question of the MAUP (modifiable areal unit ...
Nicolas Verdier, Ludovic Chalonge
doaj   +1 more source

Hijacking emergency granulopoiesis: Neutrophil ontogeny and reprogramming in cancer

open access: yesMolecular Oncology, EarlyView.
Neutrophils are highly plastic innate immune cells; their functions in cancer extend beyond the tumour microenvironment. This Review summarises current understanding of neutrophil maturation and heterogeneity and highlights tumour‐induced granulopoiesis as a systemic programme that expands immature, immunosuppressive neutrophils via tumour‐derived ...
Gabriela Marinescu, Yi Feng
wiley   +1 more source

On the axiomatic foundations of linear scale-space : Combining semi-group structure with causality vs. scale invariance

open access: yes, 1996
The notion of multi-scale representation is essential to many aspects of early visual processing. This article deals with the axiomatic formulation of the special type of multi-scale representation known as scale-space representation.
Lindeberg, Tony
core  

Remaking Sustainable Urbanism: Space, Scale and Governance in the New Urban Era

open access: yes, 2019
This book analyses the implications of eco-urbanism re-making for policy and practice under the transformational trends of economic decentralization and market reform in China. While the guiding themes are space, scale, and governance of cities, the book
Zhang, Xiaoling
core   +1 more source

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