Results 171 to 180 of about 1,321,726 (316)

Long‐term hippocampal alterations and cognitive impairment in a murine model of surgical sepsis

open access: yesFEBS Open Bio, EarlyView.
Using a mouse model of surgical sepsis, we tested long‐term memory and analyzed the transcriptome of single cells isolated from the hippocampus. Survivor mice showed worse memory, loss of certain brain cell subpopulations, and abnormal immune cell activity—suggesting that post‐sepsis brain alterations may be linked to cognitive deficits.
Dong Seong Cho   +4 more
wiley   +1 more source

Italian Technostress Creators Scale: Validation of an Assessment Tool. [PDF]

open access: yesJ Occup Environ Med
Rossi MF   +5 more
europepmc   +1 more source

Validation and treatment of missing values for the reduced WOMAC function scale

open access: yes, 2004
Introduction: The reduced WOMAC function scale has been developed and initial validity performed. However, further validation and recommendations for the treatment of missing values is required.\ud \ud Aim: To further assess the validity of the reduced ...
Crawford, Ross W.   +2 more
core  

Derivation and characterization of retinal pigment epithelium from urine‐derived iPSCs

open access: yesFEBS Open Bio, EarlyView.
Age‐related macular degeneration causes vision loss via RPE dysfunction and loss. Traditional iPSC therapies rely on invasive biopsies, limiting scalability. Here, we utilize urine‐derived stem cells as an accessible source to generate u‐iPSCs, successfully differentiated into pigmented RPE. This “Urine‐to‐Retina” platform provides a promising path for
Daniella Beiner   +7 more
wiley   +1 more source

Early‐life high‐fat diet exposure increases Achilles tendon stiffness and induces transcriptomic alterations

open access: yesFEBS Open Bio, EarlyView.
Early‐life exposure to a high‐fat diet altered intact Achilles tendons in rat offspring, making them thinner, stiffer, and molecularly distinct even without injury. These findings suggest that developmental high‐fat diet exposure may impair tendon quality and increase susceptibility to mechanical overload or tendon injury later in life.
Heyong Yin   +3 more
wiley   +1 more source

A short mental health literacy scale: validation and application in Brazil. [PDF]

open access: yesBMC Public Health
Buta BO, Couto VVD, Froner MB, Tabak BM.
europepmc   +1 more source

Adherence to treatment and harmful effects of medication shortages in the context of severe crises: scale validation and correlates. [PDF]

open access: yesJ Pharm Policy Pract, 2023
Bou Malhab S   +6 more
europepmc   +1 more source

RoundMi: A quantitative method to analyze mitochondrial morphology in mitotic cells

open access: yesFEBS Open Bio, EarlyView.
RoundMi is a workflow for rapid analysis of mitochondrial morphology in mitotic cells. By combining adaptive preprocessing with automated segmentation and quantification, it enables accurate measurements from single focal plane images, reducing acquisition time and computational demands while remaining compatible with high‐throughput fixed and live ...
Elmira Parvindokht Bararpour   +2 more
wiley   +1 more source

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