Performance of clinical judgment and prognostic scales for survival prediction in palliative care: A prospective cohort study. [PDF]
Mantilla Santamaria AF +5 more
europepmc +1 more source
A nanoscale window for probing Planck scale phenomena [PDF]
Shi‐Dong Liang
openalex +1 more source
Keratin 19 (KRT19) is overexpressed in high‐grade serous ovarian cancer with high levels of Kallikrein‐related peptidases (KLK) 4–7 and is associated with poor survival. In vivo analyses demonstrate that elevated KRT19 increases peritoneal tumour burden.
Sophia Bielesch +13 more
wiley +1 more source
Clinical Characteristics of Primary Orthostatic Tremor - a Comprehensive Clinical Assessment of Patients in Sweden. [PDF]
Af Edholm K +4 more
europepmc +1 more source
We have established a humanized orthotopic patient‐derived xenograft (Hu‐oPDX) mouse model of high‐grade serous ovarian cancer (HGSOC) that recapitulates human tumor–immune interactions. Using combined anti‐PD‐L1/anti‐CD73 immunotherapy, we demonstrate the model's improved biological relevance and enhanced translational value for preclinical ...
Luka Tandaric +10 more
wiley +1 more source
Association Between Pneumonia Risk and Anticholinergic Burden Among Patients with Different Frailty Levels [Letter]. [PDF]
Yang J, Song Y.
europepmc +1 more source
E2A selectively regulates TGF‐β–induced apoptosis in KRAS‐mutant non‐small cell lung cancer
Ability to induce apoptosis by TGF‐β is frequently lost in advanced lung adenocarcinoma despite intact TGF‐β signaling. We identify E2A as a mutant KRAS–dependent mediator of resistance to TGF‐β–induced apoptosis. TGF‐β induces E2A via SMAD3 in mutant KRAS cells, and E2A silencing restores apoptosis and enhances radiation response in cell lines ...
Sergei Chuikov +3 more
wiley +1 more source
Processed carp scales as a functional food for sepsis protection: enhancing amino acid content and bioactive peptide profiles. [PDF]
Yan L, Wang Q, Tang M.
europepmc +1 more source
Rethinking plastic waste: innovations in enzymatic breakdown of oil‐based polyesters and bioplastics
Plastic pollution remains a critical environmental challenge, and current mechanical and chemical recycling methods are insufficient to achieve a fully circular economy. This review highlights recent breakthroughs in the enzymatic depolymerization of both oil‐derived polyesters and bioplastics, including high‐throughput protein engineering, de novo ...
Elena Rosini +2 more
wiley +1 more source
<i>Aleuritopteris hainanensis</i> (Pteridaceae), a New Species From Hainan, China. [PDF]
Zhang B +7 more
europepmc +1 more source

