Results 251 to 260 of about 11,492,110 (391)

Tumour–host interactions in Drosophila: mechanisms in the tumour micro‐ and macroenvironment

Molecular Oncology, EarlyView.
This review examines how tumour–host crosstalk takes place at multiple levels of biological organisation, from local cell competition and immune crosstalk to organism‐wide metabolic and physiological collapse. Here, we integrate findings from Drosophila melanogaster studies that reveal conserved mechanisms through which tumours hijack host systems to ...
José Teles‐Reis, Tor Erik Rusten
wiley   +1 more source

A reframed landscape of causal emergence. [PDF]

Patterns (N Y)
Cawiding OR, Song YM, Kim JK.
europepmc   +1 more source

Basroparib inhibits YAP‐driven cancers by stabilizing angiomotin

Molecular Oncology, EarlyView.
Basroparib, a selective tankyrase inhibitor, suppresses Wnt signaling and attenuates YAP‐driven oncogenic programs by stabilizing angiomotin. It promotes AMOT–YAP complex formation, enforces cytoplasmic YAP sequestration, inhibits YAP/TEAD transcription, and sensitizes YAP‐active cancers, including KRAS‐mutant colorectal cancer, to MEK inhibition.
Young‐Ju Kwon, Dong Young Kim, Yuna Kim, Uk‐Il Kim, Jae‐Sung Kim   +4 more
wiley   +1 more source

Examining the Factor Structure of Objective Health Literacy and Numeracy Scales: Large-Scale Cross-Sectional Study.

JMIR Public Health Surveill
Moriishi C, Takano K, Oba T, Konishi N, Katahira K, Kimura K.   +5 more
europepmc   +1 more source

The causal structure of psychopathology and why it matters. [PDF]

World Psychiatry
Turkheimer E.
europepmc   +1 more source

RaMBat: Accurate identification of medulloblastoma subtypes from diverse data sources with severe batch effects

Molecular Oncology, EarlyView.
To integrate multiple transcriptomics data with severe batch effects for identifying MB subtypes, we developed a novel and accurate computational method named RaMBat, which leveraged subtype‐specific gene expression ranking information instead of absolute gene expression levels to address batch effects of diverse data sources.
Mengtao Sun, Jieqiong Wang, Shibiao Wan
wiley   +1 more source

Scales to measure core outcomes for the quality of dementia care in home or residential aged care facilities: a rapid review. [PDF]

BMJ Open
Dao-Tran TH, Kenny D, Welch A, Brittain D, Lendich K, Thompson J, Parkin B, Nunn JS, Vos G, Comans T.   +9 more
europepmc   +1 more source

Actin dynamics controlled by IqgC, a RasGAP at the crossroads between the IQGAP and fungal GAP1 families

FEBS Open Bio, EarlyView.
IqgC is a RasGAP from Dictyostelium discoideum. IqgC binds RasG via its RasGAP domain and deactivates it on macroendocytic cups, thereby suppressing the uptake of fluid and particles. IqgC has a positive effect on cell‐substratum adhesion, and its RGCt domain is required for recruitment to ventral foci.
Vedrana Filić, Darija Putar, Lucija Mijanović, Igor Weber   +3 more
wiley   +1 more source

Exploring the multiscale structure of urban waterlogging resilience systems for adaptive policy optimisation. [PDF]

Sci Rep
Wang Q, Zhao G, Tian J.
europepmc   +1 more source

Characterization of chromia scales formed in supercritical carbon dioxide

, 2017
Bruce A. Pint, Kinga A. Unocic, R. G. Brese, James R. Keiser   +3 more
openalex   +2 more sources