Results 41 to 50 of about 2,196,235 (269)

Lessons from World War I

open access: yesCadmus, 2014
The history of World War I is reviewed, starting with a discussion of the development of nationalist movements in Europe. It is pointed out that the global disaster started with a seemingly small operation by Austria, which escalated uncontrollably into ...
John Scales Avery
doaj  

Psychometric properties of the general conspiracy belief scale using item response theory

open access: yesJurnal Penelitian dan Evaluasi Pendidikan
Evaluation of the psychometric properties of conspiracy theory belief instruments has been dominated by classical approaches with limitations, especially in dependence on sample size and inaccuracies in item-level analysis.
Sumin Sumin   +2 more
doaj   +1 more source

Time after time – circadian clocks through the lens of oscillator theory

open access: yesFEBS Letters, EarlyView.
Oscillator theory bridges physics and circadian biology. Damped oscillators require external drivers, while limit cycles emerge from delayed feedback and nonlinearities. Coupling enables tissue‐level coherence, and entrainment aligns internal clocks with environmental cues.
Marta del Olmo   +2 more
wiley   +1 more source

El estímulo de experiencia estética mediante operaciones retóricas escalares

open access: yesArea
Las nociones de medida, tamaño, proporción y escala afloran de manera habitual en la literatura básica sobre la Arquitectura, no obstante estas referencias tienden a ser triviales o meramente operativas. El artículo revisa esos conceptos, considerándolos
Jorge Pokropek
doaj   +1 more source

Conserved structural motifs in PAS, LOV, and CRY proteins regulate circadian rhythms and are therapeutic targets

open access: yesFEBS Letters, EarlyView.
Cryptochrome and PAS/LOV proteins play intricate roles in circadian clocks where they act as both sensors and mediators of protein–protein interactions. Their ubiquitous presence in signaling networks has positioned them as targets for small‐molecule therapeutics. This review provides a structural introduction to these protein families.
Eric D. Brinckman   +2 more
wiley   +1 more source

Flaws in the Concept of Nuclear Deterrance

open access: yesCadmus, 2012
The concept of nuclear deterrence is seriously flawed, and it violates the fundamental ethical principles of all major religions. Besides being morally unacceptable, nuclear weapons are also illegal according to a historic 1996 decision of the ...
John Scales Avery
doaj  

In situ molecular organization and heterogeneity of the Legionella Dot/Icm T4SS

open access: yesFEBS Letters, EarlyView.
We present a nearly complete in situ model of the Legionella Dot/Icm type IV secretion system, revealing its central secretion channel and identifying new components. Using cryo‐electron tomography with AI‐based modeling, our work highlights the structure, variability, and mechanism of this complex nanomachine, advancing understanding of bacterial ...
Przemysław Dutka   +11 more
wiley   +1 more source

Malthus

open access: yesCadmus, 2013
T.R. Malthus' "An Essay on the Principle of Population" (1798) was one of the first systematic studies of the problem of population in relation to resources.
John Scales Avery
doaj  

Sequence determinants of RNA G‐quadruplex unfolding by Arg‐rich regions

open access: yesFEBS Letters, EarlyView.
We show that Arg‐rich peptides selectively unfold RNA G‐quadruplexes, but not RNA stem‐loops or DNA/RNA duplexes. This length‐dependent activity is inhibited by acidic residues and is conserved among SR and SR‐related proteins (SRSF1, SRSF3, SRSF9, U1‐70K, and U2AF1).
Naiduwadura Ivon Upekala De Silva   +10 more
wiley   +1 more source

Federalism and Global Governance

open access: yesCadmus, 2012
It is becoming increasingly clear that the concept of the absolutely sovereign nation-state is a dangerous anachronism in a world of thermonuclear weapons, instantaneous communication, and economic interdependence.
John Scales Avery
doaj  

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