Results 41 to 50 of about 1,637,196 (313)

Scaling Laws Do Not Scale

open access: yesProceedings of the AAAI/ACM Conference on AI, Ethics, and Society
Recent work has advocated for training AI models on ever-larger datasets, arguing that as the size of a dataset increases, the performance of a model trained on that dataset will correspondingly increase (referred to as “scaling laws”). In this paper, we draw on literature from the social sciences and machine learning to critically interrogate these ...
Fernando Diaz 0001, Michael Madaio
openaire   +2 more sources

Gut microbiome and aging—A dynamic interplay of microbes, metabolites, and the immune system

open access: yesFEBS Letters, EarlyView.
Age‐dependent shifts in microbial communities engender shifts in microbial metabolite profiles. These in turn drive shifts in barrier surface permeability of the gut and brain and induce immune activation. When paired with preexisting age‐related chronic inflammation this increases the risk of neuroinflammation and neurodegenerative diseases.
Aaron Mehl, Eran Blacher
wiley   +1 more source

Use of common carp waste for pigment production by Monascus purpureus

open access: yesKvasný průmysl, 2023
Fish processing worldwide generates a large amount of waste that has no further use. In this work, we tested the possible biotechnological use of two waste materials from common carp – waste scales and residues from filleting process.
Jan Kolek   +7 more
doaj   +1 more source

Forecasting at Scale

open access: yesThe American Statistician, 2017
Forecasting is a common data science task that helps organizations with capacity planning, goal setting, and anomaly detection. Despite its importance, there are serious challenges associated with producing reliable and high quality forecasts — especially when there are a variety of time series and analysts with expertise in time series modeling are ...
Taylor, Sean J, Letham, Benjamin
openaire   +1 more source

Valosin‐containing protein counteracts ATP‐driven dissolution of FUS condensates through its ATPase activity in vitro

open access: yesFEBS Letters, EarlyView.
Biomolecular condensates formed by fused in sarcoma (FUS) are dissolved by high ATP concentrations yet persist in cells. Using a reconstituted system, we demonstrate that valosin‐containing protein (VCP), an AAA+ ATPase, counteracts ATP‐driven dissolution of FUS condensates through its D2 ATPase activity.
Hitomi Kimura   +2 more
wiley   +1 more source

Strings at the intermediate scale or is the Fermi scale dual to the Planck scale? [PDF]

open access: yesPhysics Letters B, 1999
We show that if the string scale is identifed with the intermediate scale, $M_s=\sqrt{M_W M_{Planck}} \sim 10^{11}$ GeV, then the notorious hierarchy, $M_W/M_{Planck} \sim 10^{-16}$, can be explained using only $M_c/M_s \sim 0.01 \sim α_{GUT} $ as small input parameters, where $M_c$ is the compactification scale.
Burgess, C. P.   +2 more
openaire   +3 more sources

Diversity and complexity in neural organoids

open access: yesFEBS Letters, EarlyView.
Neural organoid research aims to expand genetic diversity on one side and increase tissue complexity on the other. Chimeroids integrate multiple donor genomes within single organoids. Self‐organising multi‐identity organoids, exogenous cell seeding, or enforced assembly of region‐specific organoids contribute to tissue complexity.
Ilaria Chiaradia, Madeline A. Lancaster
wiley   +1 more source

Implementing Measurement-Based Care for Depression: Practical Solutions for Psychiatrists and Primary Care Physicians

open access: yesNeuropsychiatric Disease and Treatment, 2021
Ran Ha Hong,1 Jill K Murphy,1 Erin E Michalak,1 Trisha Chakrabarty,1 Zuowei Wang,2 Sagar V Parikh,3 Larry Culpepper,4 Lakshmi N Yatham,1 Raymond W Lam,1,* Jun Chen5,* 1Department of Psychiatry, University of British Columbia, Vancouver, Canada; 2Hongkou ...
Hong RH   +9 more
doaj  

The Study of a Monumental Structure Ruins to the Southwest of the Cathedral Mosque in Bolgar City

open access: yesПоволжская археология, 2012
The ruins of a large brick building were revealed on the Bolgar city site to the southwest of the Cathedral mosque. The structure was studied during the 1989-1993, 2000 and 2011 excavations. It has been found that that its outer walls were built of baked
Baranov Vyacheslav S.   +2 more
doaj   +1 more source

Home - About - Disclaimer - Privacy