Results 251 to 260 of about 7,356,215 (336)

Economies of scale [PDF]

Genome Biology, 2012
openaire   +3 more sources

Targeting carbonic anhydrase IX/XII prevents the anti‐ferroptotic effect of stromal lactic acid in prostate carcinoma

Molecular Oncology, EarlyView.
In prostate carcinoma, lactic acid, secreted by highly glycolytic cancer‐associated fibroblasts, is imported into tumor cells through the MCT1 transporter and prevents RSL3 and erastin‐induced ferroptosis (A). Targeting of carbonic anhydrase IX/XII, the main extracellular pH regulators, in tumor and stromal cells reduces microenvironmental acidosis and
Elisa Pardella, Giuseppina Comito, Luigi Ippolito, Erica Pranzini, Marta Iozzo, Giulia Gangarossa, Francesca Virgilio, Silvia Bua, Alessio Nocentini, Giada Sandrini, Nicla Lorito, Marina Bacci, Gabriella Nesi, Pietro Spatafora, Sergio Serni, Claudiu T. Supuran, Andrea Morandi, Paola Chiarugi, Elisa Giannoni   +18 more
wiley   +1 more source

Scaling laws for Haralick texture features of linear gradients. [PDF]

PeerJ Comput Sci
Oprisan SA, Oprisan A.
europepmc   +1 more source

Understanding and measuring mechanical signals in the tumor stroma

FEBS Open Bio, EarlyView.
This review discusses cancer‐associated fibroblast subtypes and their functions, particularly in relation to extracellular matrix production, as well as the development of 3D models to study tumor stroma mechanics in vitro. Several quantitative techniques to measure tissue mechanical properties are also described, to emphasize the diagnostic and ...
Fàtima de la Jara Ortiz, Chiara Cimmino, Maurizio Ventre, Alessandra Cambi   +3 more
wiley   +1 more source

A Randomized Controlled Trial Assessing Full-Mouth Versus Quadrant-Based Scaling and Root Planing for Non-surgical Periodontal Therapy. [PDF]

Cureus
Gaddam D, Nagarakanti S, Sravya Sri P, Chiruvella B, R R, Gudur T.   +5 more
europepmc   +1 more source

CI. On Mr. Liston's, or the Euharmonic Scale of Musical Intervals, extended according to his tuning process, from 59 to 612 notes in the Octave; showing thus, a division of the Octave into 612 equal parts, or as nearly so, throughout, as experiments in harmonics, or the most refined musical performances, seem to require [PDF]

John Farey
openalex   +1 more source

Beyond digital twins: the role of foundation models in enhancing the interpretability of multiomics modalities in precision medicine

FEBS Open Bio, EarlyView.
This review highlights how foundation models enhance predictive healthcare by integrating advanced digital twin modeling with multiomics and biomedical data. This approach supports disease management, risk assessment, and personalized medicine, with the goal of optimizing health outcomes through adaptive, interpretable digital simulations, accessible ...
Sakhaa Alsaedi, Xin Gao, Takashi Gojobori   +2 more
wiley   +1 more source

Theoretical Model of the Island Effect in Flexible Electronics under Equal Biaxial Stretching. [PDF]

Small
Ma Z, Li T, Liu X, Wu J, Luo H, Yang Y.
europepmc   +1 more source

Bioengineering facets of the tumor microenvironment in 3D tumor models: insights into cellular, biophysical and biochemical interactions

FEBS Open Bio, EarlyView.
The tumor microenvironment is a dynamic, multifaceted complex system of interdependent cellular, biochemical, and biophysical components. Three‐dimensional in vitro models of the tumor microenvironment enable a better understanding of these interactions and their impact on cancer progression and therapeutic resistance.
Salma T. Rafik, Deniz Bakkalci, Alexander J. MacRobert, Umber Cheema   +3 more
wiley   +1 more source

Evaluation of the Adjunctive Effect of Photodynamic Therapy for the Treatment of Residual Periodontal Pockets: A Systematic Review. [PDF]

J Patient Cent Res Rev
Patil S, Miller C, Moffat R, Janes K, Janes B, Loomer PM, Licari FW.   +6 more
europepmc   +1 more source