Results 271 to 280 of about 3,449,394 (355)
Rescaling Flow Curves of Protein-Stabilized Emulsions. [PDF]
Nanomaterials (Basel)Velandia SF +5 more
europepmc +1 more source
Loss of proton‐sensing GPR4 reduces tumor progression in mouse models of colon cancer
Molecular Oncology, EarlyView.G protein‐coupled receptor 4 (GPR4) is a pH‐sensing receptor activated by acidic pH. GPR4 expression is increased in patients with inflammatory bowel disease who are at high risk of developing colorectal cancer. In mouse models, loss of GPR4 attenuated tumor progression. This correlated with increased IL2 and natural killer cell activity.
Leonie Perren +16 more
wiley +1 more source
Head injury risk prediction for vulnerable road users based on Chinese adult male head data. [PDF]
Sci RepLu Y, Bai J, Liu Y, Shu Y.
europepmc +1 more source
TRPM8 levels determine tumor vulnerability to channel agonists
Molecular Oncology, EarlyView.TRPM8 is a Ca2+ permissive channel. Regardless of the amount of its transcript, high levels of TRPM8 protein mark different tumors, including prostate, breast, colorectal, and lung carcinomas. Targeting TRPM8 with channel agonists stimulates inward calcium currents followed by emptying of cytosolic Ca2+ stores in cancer cells.
Alessandro Alaimo +18 more
wiley +1 more source
Molecular Oncology, EarlyView.The pan‐HDAC inhibitor belinostat increases the expression of the pro‐apoptotic proteins Bim, Puma, and Noxa and induces apoptosis in ovarian cancer cell lines and patient‐derived tumor organoids when used at high concentrations. Moreover, inhibiting the anti‐apoptotic proteins Bcl‐xL or Mcl‐1 sensitizes these preclinical models to the cytotoxic effect
Cécilia Thomine +10 more
wiley +1 more source
Cell-type-specific synaptic scaling mechanisms differentially contribute to associative learning
Veneto F, Kepçe A, Wu YK, Gjorgjieva J.
europepmc +1 more source
DMFFT: improving the generation quality of diffusion models using fast Fourier transform. [PDF]
Sci RepYu C, Han C, Zhang C.
europepmc +1 more source