Results 71 to 80 of about 13,236 (306)

Improving PARP inhibitor efficacy in bladder cancer without genetic BRCAness by combination with PLX51107

open access: yesMolecular Oncology, EarlyView.
Clinical trials on PARP inhibitors in urothelial carcinoma (UC) showed limited efficacy and a lack of predictive biomarkers. We propose SLFN5, SLFN11, and OAS1 as UC‐specific response predictors. We suggest Talazoparib as the better PARP inhibitor for UC than Olaparib.
Jutta Schmitz   +15 more
wiley   +1 more source

Polymerase Chain Reaction: A New Era in Detection of Periodontopathogens

open access: yesAdvances in Human Biology, 2015
Aim: Various techniques like cultural methods, Immunofluorescence and ELISA have largely been used for studies of microbial ecology. But nowdays PCR is used as a diagnostic tool that can detect even small numbers of periodontal pathogens with a high ...
Parul Aneja   +5 more
doaj  

SERUM ANTI-PHOSPHORYLCHOLINE AND ANTI-CARDIOLIPIN CONCENTRATIONS FOLLOWING PERIODONTAL SCALING AND ROOT PLANING [PDF]

open access: yes, 2006
Atherosclerosis is an insidious disease with serious morbidity and mortality including ischemic heart disease, stroke, and myocardial infarction. This condition is progressive and can start early in life eventually leading to large plaques and arterial ...
Chaston, Reve W
core   +1 more source

Using Enamel Matrix Derivative to Improve Treatment Efficacy in Periodontal Furcation Defects [PDF]

open access: yes, 2018
Purpose Furcations are complicated periodontal defects. Untreated furcations lead to loss of the involved teeth and supporting tissues. It has been demonstrated that regenerative biomaterials are beneficial in reconstruction of the bone surrounding ...
Aimetti   +10 more
core   +2 more sources

LINC01116, a hypoxia‐lncRNA marker of pathological lymphangiogenesis and poor prognosis in lung adenocarcinoma

open access: yesMolecular Oncology, EarlyView.
The LINC01116 long noncoding RNA is induced by hypoxia and associated with poor prognosis and high recurrence rates in two cohorts of lung adenocarcinoma patients. Here, we demonstrate that besides its expression in cancer cells, LINC01116 is markedly expressed in lymphatic endothelial cells of the tumor stroma in which it participates in hypoxia ...
Marine Gautier‐Isola   +12 more
wiley   +1 more source

Comparative Evaluation Effectiveness of Er:YAG Lazer, Manual and Ultrasonic Devises in SRP of the Root Surfaces with SEM Method

open access: yesمجله دانشکده دندانپزشکی اصفهان, 2006
Introduction: Scaling and root planing is one of the most commonly used procedures during periodontal treatments. Removal of calculus using conventional hand instruments is incomplete and rather time consuming.
R - Birang   +2 more
doaj  

Efektivitas antara Scaling Root Planing (Srp) dengan dan tanpa Pemberian Ciprofloxacin Per Oral pada Penderita Periodontitis [PDF]

open access: yes, 2012
Periodontitis adalah suatu penyakit infeksi pada jaringan pendukung gigi disebabkan mikroorganisme menyebabkan kerusakan progresif pada ligamen periodontal dan tulang alveolar, jika tidak dilakukan perawatan yang tepat dapat mengakibatkan kehilangan gigi.
Andriani, I. (Ika)
core  

Developing evidence‐based, cost‐effective P4 cancer medicine for driving innovation in prevention, therapeutics, patient care and reducing healthcare inequalities

open access: yesMolecular Oncology, EarlyView.
The cancer problem is increasing globally with projections up to the year 2050 showing unfavourable outcomes in terms of incidence and cancer‐related deaths. The main challenges are prevention, improved therapeutics resulting in increased cure rates and enhanced health‐related quality of life.
Ulrik Ringborg   +43 more
wiley   +1 more source

Characteristics of a series of high speed hard chine planing hulls - part II: performance in waves

open access: yes, 2011
An experimental investigation into the performance of high speed hard chine planing hulls in irregular waves has been conducted. A new series of models representative of current design practice was developed and tested experimentally. Measurements of the
Hudson, D.A.   +2 more
core   +1 more source

Cell surface interactome analysis identifies TSPAN4 as a negative regulator of PD‐L1 in melanoma

open access: yesMolecular Oncology, EarlyView.
Using cell surface proximity biotinylation, we identified tetraspanin TSPAN4 within the PD‐L1 interactome of melanoma cells. TSPAN4 negatively regulates PD‐L1 expression and lateral mobility by limiting its interaction with CMTM6 and promoting PD‐L1 degradation.
Guus A. Franken   +7 more
wiley   +1 more source

Home - About - Disclaimer - Privacy