Results 101 to 110 of about 185,241 (309)

Structural insights into an engineered feruloyl esterase with improved MHET degrading properties

open access: yesFEBS Letters, EarlyView.
A feruloyl esterase was engineered to mimic key features of MHETase, enhancing the degradation of PET oligomers. Structural and computational analysis reveal how a point mutation stabilizes the active site and reshapes the binding cleft, expading substrate scope.
Panagiota Karampa   +5 more
wiley   +1 more source

Limit Distributions and Scaling Functions [PDF]

open access: yes, 2009
We discuss the asymptotic behaviour of models of lattice polygons, mainly on the square lattice. In particular, we focus on limiting area laws in the uniform perimeter ensemble where, for fixed perimeter, each polygon of a given area occurs with the same probability. We relate limit distributions to the scaling behaviour of the associated perimeter and
openaire   +2 more sources

Gut microbiome and aging—A dynamic interplay of microbes, metabolites, and the immune system

open access: yesFEBS Letters, EarlyView.
Age‐dependent shifts in microbial communities engender shifts in microbial metabolite profiles. These in turn drive shifts in barrier surface permeability of the gut and brain and induce immune activation. When paired with preexisting age‐related chronic inflammation this increases the risk of neuroinflammation and neurodegenerative diseases.
Aaron Mehl, Eran Blacher
wiley   +1 more source

Asymptotics of spin-spin correlators weighted by fermion number measurements with low rapidity threshold in the 2D Ising free-fermion QFT

open access: yesJournal of High Energy Physics
In the work, we study the averaged number of massive fermions above a low rapidity threshold Y, underlying the form-factor expansions of the spin-spin two-point correlators at an Euclidean distance r, in the 2D Ising QFT at the free massive fermion point.
Yizhuang Liu
doaj   +1 more source

Nonlinear response in diffusive systems

open access: yesSciPost Physics
Nonintegrable systems thermalize, leading to the emergence of fluctuating hydrodynamics. Typically, this hydrodynamics is diffusive. We use the effective field theory (EFT) of diffusion to compute higher-point functions of conserved densities. We uncover
Luca V. Delacrétaz, Ruchira Mishra
doaj   +1 more source

Valosin‐containing protein counteracts ATP‐driven dissolution of FUS condensates through its ATPase activity in vitro

open access: yesFEBS Letters, EarlyView.
Biomolecular condensates formed by fused in sarcoma (FUS) are dissolved by high ATP concentrations yet persist in cells. Using a reconstituted system, we demonstrate that valosin‐containing protein (VCP), an AAA+ ATPase, counteracts ATP‐driven dissolution of FUS condensates through its D2 ATPase activity.
Hitomi Kimura   +2 more
wiley   +1 more source

Scaling and Proximity Properties of Integrally Convex Functions [PDF]

open access: yes, 2016
In discrete convex analysis, the scaling and proximity properties for the class of L^natural-convex functions were established more than a decade ago and have been used to design efficient minimization algorithms.
Moriguchi, Satoko   +3 more
core   +1 more source

Pre-equilibrium Photon and Dilepton Production [PDF]

open access: yesEPJ Web of Conferences
We use QCD kinetic theory to compute photon and dilepton production in the chemically equilibrating out-of-equilibrium quark-gluon plasma created in the early stages of high-energy heavy-ion collisions.
Garcia-Montero Oscar   +3 more
doaj   +1 more source

Body region-specific 3D age-scaling functions for scaling whole-body computed tomography anatomy for pediatric late effects studies. [PDF]

open access: yesBiomed Phys Eng Express, 2022
Gupta AC   +13 more
europepmc   +1 more source

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