Results 101 to 110 of about 146,038 (305)

The (Glg)ABCs of cyanobacteria: modelling of glycogen synthesis and functional divergence of glycogen synthases in Synechocystis sp. PCC 6803

open access: yesFEBS Letters, EarlyView.
We reconstituted Synechocystis glycogen synthesis in vitro from purified enzymes and showed that two GlgA isoenzymes produce glycogen with different architectures: GlgA1 yields denser, highly branched glycogen, whereas GlgA2 synthesizes longer, less‐branched chains.
Kenric Lee   +3 more
wiley   +1 more source

Scaling limist of critical directed graphs

open access: yes
The scaling limit of connected components in critical undirected random graphs has been well studied and shown to be universal between different critical models of undirected random graphs.
Xie, Zheneng
core   +1 more source

Structural insights into an engineered feruloyl esterase with improved MHET degrading properties

open access: yesFEBS Letters, EarlyView.
A feruloyl esterase was engineered to mimic key features of MHETase, enhancing the degradation of PET oligomers. Structural and computational analysis reveal how a point mutation stabilizes the active site and reshapes the binding cleft, expading substrate scope.
Panagiota Karampa   +5 more
wiley   +1 more source

Gut microbiome and aging—A dynamic interplay of microbes, metabolites, and the immune system

open access: yesFEBS Letters, EarlyView.
Age‐dependent shifts in microbial communities engender shifts in microbial metabolite profiles. These in turn drive shifts in barrier surface permeability of the gut and brain and induce immune activation. When paired with preexisting age‐related chronic inflammation this increases the risk of neuroinflammation and neurodegenerative diseases.
Aaron Mehl, Eran Blacher
wiley   +1 more source

String/Gauge Duality and Penrose Limit [PDF]

open access: yes, 2003
Berenstein, Maldacena, and Nastase have recently discovered a particular limit of AdS/CFT correspondence where string theory in a plane wave background is dual to a sector of $mathcal N =4 SYM in a double scaling limit.
Park, Jongwon
core   +1 more source

The quasi-steady state of the valley wind system

open access: yesFrontiers in Earth Science, 2015
The quasi-steady-state limit of the diurnal valley wind system is investigated overidealized three-dimensional topography. Although this limit is rarely attained inreality due to ever-changing forcings, the investigation of this limit canprovide valuable
Juerg eSchmidli   +2 more
doaj   +1 more source

Valosin‐containing protein counteracts ATP‐driven dissolution of FUS condensates through its ATPase activity in vitro

open access: yesFEBS Letters, EarlyView.
Biomolecular condensates formed by fused in sarcoma (FUS) are dissolved by high ATP concentrations yet persist in cells. Using a reconstituted system, we demonstrate that valosin‐containing protein (VCP), an AAA+ ATPase, counteracts ATP‐driven dissolution of FUS condensates through its D2 ATPase activity.
Hitomi Kimura   +2 more
wiley   +1 more source

Diversity and complexity in neural organoids

open access: yesFEBS Letters, EarlyView.
Neural organoid research aims to expand genetic diversity on one side and increase tissue complexity on the other. Chimeroids integrate multiple donor genomes within single organoids. Self‐organising multi‐identity organoids, exogenous cell seeding, or enforced assembly of region‐specific organoids contribute to tissue complexity.
Ilaria Chiaradia, Madeline A. Lancaster
wiley   +1 more source

NOVEL NUMERICAL PROCEDURES FOR LIMIT ANALYSIS OF STRUCTURES: MESH-FREE METHODS AND MATHEMATICAL PROGRAMMING [PDF]

open access: yes, 2010
Current research in the field of limit analysis is focussing on the development of numerical tools which are sufficiently efficient and robust to be used in engineering practice.
Le, Canh
core  

Three helium atoms and the scaling limit

open access: yes, 1999
We show that a scaling limit approach, previously applied in three-body low-energy nuclear physics, is realized for the first excited state of He-4 trimer.
Delfino, A.   +7 more
core   +1 more source

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