Results 141 to 150 of about 146,038 (305)

A General Solution to the Continuum Rate Equation for Island-Size Distributions: Epitaxial Growth Kinetics and Scaling Analysis

Nanomaterials
The nucleation and growth of surface islands in the pre-coalescence stage has previously been studied by different methods, including the rate equation approach and kinetic Monte Carlo simulations.
Vladimir G. Dubrovskii
doaj   +1 more source

A SCALING LIMIT FOR t-SCHUR MEASURES

Kyushu Journal of Mathematics, 2005
We introduce a generalization of the Schur measure. And we give a combinatorial interpretation to this generalized measure and prove that a scaling limit for this measure is given by the Tracy-Widom distribution.
openaire   +4 more sources

Tumour–host interactions in Drosophila: mechanisms in the tumour micro‐ and macroenvironment

Molecular Oncology, EarlyView.
This review examines how tumour–host crosstalk takes place at multiple levels of biological organisation, from local cell competition and immune crosstalk to organism‐wide metabolic and physiological collapse. Here, we integrate findings from Drosophila melanogaster studies that reveal conserved mechanisms through which tumours hijack host systems to ...
José Teles‐Reis, Tor Erik Rusten
wiley   +1 more source

Dimethyl fumarate combined with cisplatin at subcytotoxic doses sensitizes cervical cancer toward ferroptosis and apoptosis through GSH restriction and p53 (re)activation

Molecular Oncology, EarlyView.
Dimethyl fumarate (DMF) reduces growth of HPV‐positive cervical cancer spheroids and induces ferroptosis in cervical cancer cells via blocking SLC7A11/Glutathione (GSH) axis. Combination of subcytotoxic doses of DMF and cisplatin (CDDP) further suppresses spheroid growth and drives cell death in 2D culture models.
Carolina Punziano, Giuseppina Minopoli, Simona Romano, Laura Marrone, Katia Aquilano, Maria Lina Tornesello, Raffaella Faraonio   +6 more
wiley   +1 more source

SPDE limits of the random walk Metropolis algorithm in high dimensions [PDF]

, 2009
Diffusion limits of MCMC methods in high dimensions provide a useful theoretical tool for studying efficiency. In particular they facilitate precise estimates of the number of steps required to explore the target measure, in stationarity, as a ...
Mattingly, Jonathan C., Pillai, Natesh S., Stuart, A. M.   +2 more
core  

Network divergence analysis identifies adaptive gene modules and two orthogonal vulnerability axes in pancreatic cancer

Molecular Oncology, EarlyView.
Tumors contain diverse cellular states whose behavior is shaped by context‐dependent gene coordination. By comparing gene–gene relationships across biological contexts, we identify adaptive transcriptional modules that reorganize into distinct vulnerability axes.
Brian Nelson, Lyanne Delgado‐Coka, Natalia Marchenko, Luisa F. Escobar‐Hoyos, Kenneth R. Shroyer, Alisa Yurovsky, Trey Ideker, Gábor Balázsi, Thomas MacCarthy, Scott Powers   +9 more
wiley   +1 more source

COMP–PMEPA1 axis promotes epithelial‐to‐mesenchymal transition in breast cancer cells

Molecular Oncology, EarlyView.
This study reveals that cartilage oligomeric matrix protein (COMP) promotes epithelial‐to‐mesenchymal transition (EMT) in breast cancer. We identify PMEPA1 (protein TMEPAI) as a novel COMP‐binding partner that mediates EMT via binding to the TSP domains of COMP, establishing the COMP–PMEPA1 axis as a key EMT driver in breast cancer.
Konstantinos S. Papadakos, Gilar Gorji‐bahri, Lejla Gradjan, Julia Zajac, Kacper Gil, Yvonne Thokozile Nduku, Anna M. Blom   +6 more
wiley   +1 more source

Hydrodynamic scaling limit of the continuum solid-on-solid model

, 2004
In this thesis we compute the hydrodynamic scaling limit of the continuum solid-on-solid model. The model, also known as the fourth order Ginzburg-Landau model, has been built to understand the relaxation to equilibrium of a crystal surface through ...
Savu, Anamaria
core  

Pre‐analytical optimization of cell‐free DNA and extracellular vesicle‐derived DNA for mutation detection in liquid biopsies

Molecular Oncology, EarlyView.
Pre‐analytical handling critically determines liquid biopsy performance. This study defines practical best‐practice conditions for cell‐free DNA (cfDNA) and extracellular vesicle–derived DNA (evDNA), showing how processing time, storage conditions, tube type, and plasma input volume affect DNA integrity and mutation detection.
Jonas Dohmen, Lucrezia De Santis, Bret M. Stephens, Vincent Bernard, Jörg C. Kalff, Lara Braun, Phillipp Leyendecker, Johannes Röttgen, Daniel Weissinger, Anirban Maitra, Paola A. Guerrero, Alexander Semaan   +11 more
wiley   +1 more source

Scaling limit of first passage percolation geodesics on planar maps

51 pages, 8 figuresWe establish the scaling limit of the geodesics to the root for the first passage percolation distance on random planar maps. We first describe the scaling limit of the number of faces along the geodesics.
Kammerer, Emmanuel
core   +1 more source