Results 171 to 180 of about 146,038 (305)

Adaptor protein CIN85 potentiates the motility of osteosarcoma cells via the Akt/mTOR and MMP2‐COL3A1 axis

Molecular Oncology, EarlyView.
CIN85 is highly expressed in osteosarcoma, particularly in metastatic lesions. Its overexpression increases cell migration and Matrigel invasion, while silencing CIN85 suppresses these behaviors. Transcriptome analysis shows that CIN85 regulates MMP2, COL3A1, and Akt/mTOR signaling. Targeting these pathways reverses CIN85‐induced motility, highlighting
Iryna Horak, Iva Staniczková Zambo, Matěj Přikryl, Peter Múdry, Danica Zapletalová, Jarmila Navrátilová, Jiří Navrátil, Jan Šmarda, Liudmyla Drobot, Petr Beneš, Lucia Knopfová   +10 more
wiley   +1 more source

Flexible active-matrix micro-LED display with 1T-1FeMFET architecture featuring scaling-limit-free design. [PDF]

Nat Commun
Huang T, Yang G, Sang Y, Zhuo F, Liu M, Li G, Cheng H, Yu Z, Fu Z, Liu S, Shen H, Yu Z, Liu B, Wang X, Wu W, Shi R, Zhuang Z, Sun W.   +17 more
europepmc   +1 more source

Longitudinal circulating tumor DNA profiling in patients with advanced endometrial cancer using an off‐the‐shelf targeted NGS panel

Molecular Oncology, EarlyView.
Intratumour heterogeneity complicates precision management of advanced endometrial cancer. Circulating tumor DNA (ctDNA) offers a minimally invasive strategy to capture tumor evolution and therapeutic resistance. Here, we compare tumor‐agnostic NGS with tumor‐informed ddPCR, outlining their relative sensitivity, concordance, and clinical implications ...
Carlos Casas‐Arozamena, Karin Teien Lande, Eva Diaz, Ana Vilar, Juan Cueva, Efigenia Arias, Victoria Sampayo, Alicia Abalo, Nerea González, Eva Colás, Antonio Gil‐Moreno, Miguel Abal, Gema Moreno‐Bueno, Therese Sørlie, Kristina Lindemann, Laura Muinelo‐Romay   +15 more
wiley   +1 more source

Critical percolation in the plane : I. Conformal invariance and Cardy's formula. II. Continuum scaling limit

, 2001
We study scaling limits and conformal invariance of critical site percolation on triangular lattice. We show that some percolation-related quantities are harmonic conformal invariants, and calculate their values in the scaling limit. As a particular case
Smirnov, Stanislav
core  

Interaction of HS1BP3 with cortactin modulates TKS5 localisation, cell secretion and cancer malignancy

Molecular Oncology, EarlyView.
Here, we demonstrate that HS1BP3 interacts with Cortactin through a proline‐rich region (PRR3.1) and show that this interaction, and HS1BP3 itself, promote cancer cell proliferation and invasion. Inhibition of this interaction leads to build‐up of TKS5 in multivesicular endosomes and altered secretion of CD63 and CD9, providing an explanation for the ...
Arja Arnesen Løchen, Kristiane Søreng, Chiara Veroni, Laura Trachsel‐Moncho, Nagham Asp, Robin Gaupset, Lars Gustav Lyckander, Helene Knævelsrud, Lars Eftang, Anne Simonsen   +9 more
wiley   +1 more source

The CRT is the scaling limit of unordered binary trees

, 2011
International audienceWe prove that a uniform, rooted unordered binary tree with $n$ vertices has the Brownian continuum random tree as its scaling limit for the Gromov-Hausdorff topology.
Miermont, Grégory, Marckert, Jean-François   +1 more
core  

The GHP Scaling Limit of Uniform Spanning Trees in High Dimensions. [PDF]

Commun Math Phys
Archer E, Nachmias A, Shalev M.
europepmc   +1 more source

Proteasome inhibitor, ixazomib prevents topoisomerase‐I degradation and reverses irinotecan resistance in colorectal cancer

Molecular Oncology, EarlyView.
Ixazomib inhibits proteasome‐mediated degradation of topoisomerase I induced by irinotecan, thereby restoring drug sensitivity and promoting tumor cell death in colorectal cancer. Irinotecan, a topoisomerase I (topoI) inhibitor, is widely used for colorectal cancer, but resistance remains a major clinical challenge.
Yuho Ebata, Koji Ando, Hirofumi Hasuda, Koshi Mimori, Elizabeth C. Unan, Siddhartha Pulukuri, Aahana Tiku, Allison Berger, Eiji Oki, Ajit Bharti, Tomoharu Yoshizumi   +10 more
wiley   +1 more source

Exploiting Space Diversity and Dynamic Voltage Frequency Scaling in Multiplane Network-on-Chips [PDF]

, 2012
Mario Roberto Casu, Paolo Giaccone, Nanfang Li, CASU, MARIO ROBERTO, Giaccone, Paolo, LI, NANFANG, Nanfang, Li, Andrea Bianco, Bianco, Andrea   +8 more
core   +1 more source

Microstructures and scaling limits

Rendiconti di Matematica e delle Sue Applicazioni, 2007
These are notes of a Colloquium given on May 30, 2005, at the Mathematical Department of the University of Roma La Sapienza. The notes based on researches of the author in statistical mechanics are intended to underline contiguities with other disciplines as probability theory, calculus of variations, geometrical measure theory, PDE ...
openaire   +1 more source