Results 191 to 200 of about 102,318 (263)

ZW4864‐mediated inhibition of the β‐catenin/BCL9/BCL9L complex reveals therapeutic potential in bladder cancer

Molecular Oncology, EarlyView.
BCL9 and BCL9L drive bladder cancer progression by enhancing β‐catenin signaling, promoting proliferation, migration, invasion, and organoid growth. Genetic depletion of BCL9(L) suppresses malignant phenotypes, while pharmacological disruption of the β‐catenin/BCL9(L) complex with ZW4864 inhibits canonical Wnt signaling and tumor‐associated cellular ...
Roland Kotolloshi, Mandy Berndt‐Paetz, Eileen Lerner, Gregoire Najjar, Anca Azoitei, Krishna Pal Singh, Shailendra Kumar Gupta, Olaf Wolkenhauer, Cagatay Günes, Otmar Huber, Marc‐Oliver Grimm, Daniel Steinbach   +11 more
wiley   +1 more source

Refractory postoperative eczematous dermatitis after total auricular reconstruction, temporally associated with povidone-iodine: a case report. [PDF]

Front Pediatr
Lu S, Xia X, Wang C, Zou J, Shen W.
europepmc   +1 more source

Automated FRAP microscopy for high‐throughput analysis of protein dynamics in chromatin organization and transcription

FEBS Open Bio, EarlyView.
RoboMic is an automated confocal microscopy pipeline for high‐throughput functional imaging in living cells. Demonstrated with fluorescence recovery after photobleaching (FRAP), it integrates AI‐driven nuclear segmentation, ROI selection, bleaching, and analysis.
Selçuk Yavuz, Bart Geverts, Johan A. Slotman, Andrea Sacchetti, Stefan Prekovic, Martin E. van Royen, Adriaan B. Houtsmuller   +6 more
wiley   +1 more source

Estimating Lumbar Spine Foraminal Disc Measurements Using Ultrasound and X-Ray Imaging Through Advanced Image Annotation, Processing, and Mathematical Modeling During Chiropractic Traction Procedures: A Feasibility Study. [PDF]

Bioengineering (Basel)
Bhagi C, Gudavalli MR, Kruse RA, Cox JM.
europepmc   +1 more source

Raman‐based label‐free microscopic analysis of the pancreas in living zebrafish larvae

FEBS Open Bio, EarlyView.
Forward stimulated Raman scattering (F‐SRS) and epi coherent anti‐Stokes Raman scattering (E‐CARS) allow label‐free discrimination of distinct subcellular structures in the pancreas of living zebrafish larvae. Given the straightforward applicability, we anticipate broad implementation of Raman microscopy in other organs and across various biomedical ...
Noura Faraj, Eline M. F. de Lange, Klaas A. Sjollema, Ben N. G. Giepmans   +3 more
wiley   +1 more source

Scaling Limits of Algorithms on Large Matrices

Thesis (Ph.D.)--University of Washington, 2024Advances in large-scale machine learning have been driven by simple and lightweight iterative algorithms.
Somani, Raghav
core  

Certolizumab pegol induced paradoxical psoriatic alopecia with therapeutic response to bimekizumab. [PDF]

An Bras Dermatol
Taş Aygar G, Keleş F, Biber FE, Han U, Kartal SP.   +4 more
europepmc   +1 more source

Mycobacterial cell division arrest and smooth‐to‐rough envelope transition using CRISPRi‐mediated genetic repression systems

FEBS Open Bio, EarlyView.
CRISPRI‐mediated gene silencing and phenotypic exploration in nontuberculous mycobacteria. In this Research Protocol, we describe approaches to control, monitor, and quantitatively assess CRISPRI‐mediated gene silencing in M. smegmatis and M. abscessus model organisms.
Vanessa Point, Wafaa Achache, Janïs Laudouze, Eliana Sepulveda Ramos, Mickaël Maziero, Céline Crauste, Stéphane Canaan, Pierre Santucci   +7 more
wiley   +1 more source

Uniform attachment with freezing: Scaling limits

We investigate scaling limits of trees built by uniform attachment with freezing, which is a variant of the classical model of random recursive trees introduced in a companion paper.
Kortchemski, Igor, Kammerer, Emmanuel, Blanc-Renaudie, Arthur, Bellin, Étienne   +3 more
core  

Challenges and prospects of 2D electronics for future monolithic complementary field-effect transistors. [PDF]

Nat Commun
Islam MM, Cho Y, Sen A, Bisht P, Shim J, Oh JO, Park G, Rossi A, Lee H, Jiang L, Coletti C, Park BI, Chae H, Shin S, Park H, Kim S.   +15 more
europepmc   +1 more source