Results 201 to 210 of about 339,768 (366)

Longitudinal circulating tumor DNA profiling in patients with advanced endometrial cancer using an off‐the‐shelf targeted NGS panel

open access: yesMolecular Oncology, EarlyView.
Intratumour heterogeneity complicates precision management of advanced endometrial cancer. Circulating tumor DNA (ctDNA) offers a minimally invasive strategy to capture tumor evolution and therapeutic resistance. Here, we compare tumor‐agnostic NGS with tumor‐informed ddPCR, outlining their relative sensitivity, concordance, and clinical implications ...
Carlos Casas‐Arozamena   +15 more
wiley   +1 more source

Scaling LLM Test-Time Compute Optimally can be More Effective than Scaling Model Parameters

open access: yes
Enabling LLMs to improve their outputs by using more test-time computation is a critical step towards building generally self-improving agents that can operate on open-ended natural language.
Xu, Kelvin   +3 more
core  

Methods for Scaling Icing Test Conditions

open access: yes, 1995
This report presents the results of tests at NASA Lewis to evaluate several methods to establish suitable alternative test conditions when the test facility limits the model size or operating conditions. The first method was proposed by Olsen.
Anderson, David N.
core  

Interaction of HS1BP3 with cortactin modulates TKS5 localisation, cell secretion and cancer malignancy

open access: yesMolecular Oncology, EarlyView.
Here, we demonstrate that HS1BP3 interacts with Cortactin through a proline‐rich region (PRR3.1) and show that this interaction, and HS1BP3 itself, promote cancer cell proliferation and invasion. Inhibition of this interaction leads to build‐up of TKS5 in multivesicular endosomes and altered secretion of CD63 and CD9, providing an explanation for the ...
Arja Arnesen Løchen   +9 more
wiley   +1 more source

Change and invariance in EU aggregate financial statement data

open access: yes, 2001
Aggregate accounting data from the BACH data base for European manufacturing companies is used to explore the nature of the differences in financial structure between eleven countries in the European Union over the period 1986-1999.
Serrano Cinca, C.   +2 more
core  

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