Results 201 to 210 of about 1,653,695 (312)

Scaling up multidrug-resistant tuberculosis care in China

The Lancet Global Health, 2015
Karen R Jacobson, Lora L Sabin
doaj   +1 more source

Scaling up microdroplet production with post-array devices. [PDF]

Biomicrofluidics
Masui S, Kanno Y, Nisisako T.
europepmc   +1 more source

Cell surface interactome analysis identifies TSPAN4 as a negative regulator of PD‐L1 in melanoma

Molecular Oncology, EarlyView.
Using cell surface proximity biotinylation, we identified tetraspanin TSPAN4 within the PD‐L1 interactome of melanoma cells. TSPAN4 negatively regulates PD‐L1 expression and lateral mobility by limiting its interaction with CMTM6 and promoting PD‐L1 degradation.
Guus A. Franken, Andrea Abel Gutierrez, Imke van Rossum, Cornelia G. Spruijt, Michiel Vermeulen, Guido van Mierlo, Blanca Scheijen, Annemiek B. van Spriel   +7 more
wiley   +1 more source

A quality improvement approach to scaling up a complex health system intervention for the prevention and management of cardiovascular disease in rural Indonesia. [PDF]

PLOS Glob Public Health
Gadsden T, Sujarwoto S, Salsabilla SA, Maharani A, Praveen D, Tampubolon G, Abimbola S, Patel A, Palagyi A.   +8 more
europepmc   +1 more source

Scaling up nutrition for a more resilient Mali : nutrition diagnostics and costed plan for scaling up

, 2015
Meera Shekar, Max Mattern, Patrick Eozenou, Julia Dayton Eberwein, Jonathan Kweku Akuoku, Emanuela di Gropello, Wendy Karamba   +6 more
openalex   +1 more source

PARP inhibition and pharmacological ascorbate demonstrate synergy in castration‐resistant prostate cancer

Molecular Oncology, EarlyView.
Pharmacologic ascorbate (vitamin C) increases ROS, disrupts cellular metabolism, and induces DNA damage in CRPC cells. These effects sensitize tumors to PARP inhibition, producing synergistic growth suppression with olaparib in vitro and significantly delayed tumor progression in vivo. Pyruvate rescue confirms ROS‐dependent activity.
Nicolas Gordon, Peter T. Gallagher, Orly I. Richter, Neermala Poudel Neupane, Amy C. Mandigo, Jennifer J. McCann, Emanuela Dylgjeri, Irina Vasilevskaya, Christopher McNair, Channing J. Paller, Wm. Kevin Kelly, Karen E. Knudsen, Matthew J. Schiewer, Ayesha A. Shafi   +13 more
wiley   +1 more source

Scaling up from sentience: modularity, conscious broadcast, and a constitutive solution to the combination problem. [PDF]

Front Psychol
Lacalli T.
europepmc   +1 more source

Scaling BIM implementation up from housing pilot projects

, 2019
Tuomas Hykkönen
openalex   +1 more source

Safety and Efficacy of a Novel Transbronchial Radiofrequency Ablation System For Lung Tumors: One Year Follow-Up from the First Multicenter Large-Scale Clinical Trial (BRONC-RFII)

Changhao Zhong, Jiayuan Sun, Enguo Chen, Zhuquan Su, Difei Chen, Feng Wang, Xiaoping Wang, Guangnan Liu, Xiaoju Zhang, Fengming Luo, Nan Zhang, Hongwu Wang, Longyu Jin, Fa Long, Chunfang Liu, Shiman Wu, Qing Geng, Xiang Wang, Chunli Tang, Ruchong Chen, Felix Herth, Shiyue Li   +21 more
openalex   +1 more source

LDAcoop: Integrating non‐linear population dynamics into the analysis of clonogenic growth in vitro

Molecular Oncology, EarlyView.
Limiting dilution assays (LDAs) quantify clonogenic growth by seeding serial dilutions of cells and scoring wells for colony formation. The fraction of negative wells is plotted against cells seeded and analyzed using the non‐linear modeling of LDAcoop.
Nikko Brix, Daniel Samaga, Katharina Gehr, Benedek Dankó, Mohamed Schumann, Guido Drexler, Ahmed Alnatsha, Georg Beyer, Ujjwal Mahajan, Martin Selmansberger, Julia Mayerle, Claus Belka, Horst Zitzelsberger, Kirsten Lauber   +13 more
wiley   +1 more source