Results 211 to 220 of about 14,169,777 (290)

Evaluation of synaptotagmin‐1 action models by all‐atom molecular dynamics simulations

FEBS Open Bio, EarlyView.
We used molecular dynamics simulations to test models proposing that synaptotagmin‐1 facilitates membrane fusion by perturbing lipid bilayers, inducing membrane curvature and/or bridging membranes. The simulations show that synaptotagmin‐1 C2‐domains placed near the site of fusion hinder the ability of SNARE complexes to bring the membranes together ...
Josep Rizo, Klaudia Jaczynska, Christian Rosenmund   +2 more
wiley   +1 more source

Barriers and facilitators to scaling up medications for opioid use disorder in Kentucky: qualitative perspectives of treatment organization staff. [PDF]

Subst Abuse Treat Prev Policy
Knudsen HK, Andrews-Higgins S, Back-Haddix S, Lofwall MR, Fanucchi L, Walsh SL.   +5 more
europepmc   +1 more source

Scale-up of the nitridation and sintering of silicon preforms using microwave heating

, 1996
J.O. Jr. Kiggans, T.N. Tiegs, C.C. Davisson, M.S. Morrow, G.J. Garvey   +4 more
openalex   +2 more sources

Comparative activity of dimethyl fumarate derivative IDMF in three models relevant to multiple sclerosis and psoriasis

FEBS Open Bio, EarlyView.
IDMF is a derivative of dimethyl fumarate (DMF) with a unique therapeutic potential at the intersection of psoriasis and multiple sclerosis. Here, we demonstrate that it compares favorably with DMF and its other derivatives, such as Diroximel, in the zebrafish, microglia, and lymphocyte models.
Yulin He, Guiyi Gong, Geovani Quijas, Simon Ming‐Yuen Lee, Ratan K. Chaudhuri, Krzysztof Bojanowski   +5 more
wiley   +1 more source

Understanding and overcoming geographical barriers for scaling up dog vaccinations against rabies. [PDF]

Sci Rep
Sambo M, Hampson K, Johnson PCD, Johnson OO.   +3 more
europepmc   +1 more source

Dissolution testing as a quality control tool during scale-up of immediate release oral, solid dosage forms

, 1995
Glenn A. Van Buskirk
openalex   +1 more source

Industrial Scale-Up of Countercurrent Chromatography: Predictive Scale-Up [PDF]

, 2001
Ian Sutherland, Les Brown, A. S. Graham, G. G. Guillon, David J. Hawes, Lee Janaway, R. G. Whiteside, Philip Wood   +7 more
openalex   +1 more source

Pharmacological effects of osimertinib on a chicken chorioallantoic membrane xenograft model with the EGFR exon‐19‐deleted advanced NSCLC mutation

FEBS Open Bio, EarlyView.
Osimertinib reduces angiogenesis and PDL1 expression in in ovo tumors, transforming them into ‘cold tumors’ with lower immune activity. Anatomopathological and transcriptomic analyses highlight its therapeutic impact on tumor biology. This study underscores osimertinib's potential to reshape the tumor microenvironment and provides insights into its ...
David Barthélémy, Arnaud Vigneron, Xavier Rousset, Jérome Guitton, Emmanuel Grolleau, Margaux Raffin, Julie Balandier, Gaëlle Lescuyer, Mathilde Bardou, Florence Geiguer, Sébastien Couraud, Claire Bardel, Jean Viallet, Nazim Benzerdjeb, Léa Payen   +14 more
wiley   +1 more source

Scaling up access to antiretroviral treatment for HIV: lessons from a key populations program in Nigeria. [PDF]

AIDS Res Ther
Salihu A, Jahun I, Oyedeji DO, Fajemisin W, Idogho O, Shehu S, Yakubu A, Anyanti J.   +7 more
europepmc   +1 more source

Effect of Wettability on Scale-Up of Multiphase Flow From Core-Scale to Reservoir Fine-Grid Scale

, 1999
Yeun‐Chung Chang, V. Mani, K. K. Mohanty   +2 more
openalex   +2 more sources