Results 231 to 240 of about 1,653,695 (312)

Scaling up HIV treatment -Karnataka, India experience

Retrovirology, 2012
Fahim Salma, Shastri Suresh, Washington Reynold   +2 more
doaj   +1 more source

Scaling up WelTel: an evidence-based, patient-centred mHealth intervention

Annals of Global Health, 2015
L. Mwai
doaj   +1 more source

Economic evaluations of scaling up strategies of evidence-based health interventions: a systematic review. [PDF]

BMC Health Serv Res
Bankolé A, Conombo B, Légaré F, Laberge M.   +3 more
europepmc   +1 more source

Dammarenediol II enhances etoposide‐induced apoptosis by targeting O‐GlcNAc transferase and Akt/GSK3β/mTOR signaling in liver cancer

Molecular Oncology, EarlyView.
Etoposide induces DNA damage, activating p53‐dependent apoptosis via caspase‐3/7, which cleaves PARP1. Dammarenediol II enhances this apoptotic pathway by suppressing O‐GlcNAc transferase activity, further decreasing O‐GlcNAcylation. The reduction in O‐GlcNAc levels boosts p53‐driven apoptosis and influences the Akt/GSK3β/mTOR signaling pathway ...
Jaehoon Lee, Byung‐Cheol Han, Gi‐Bang Koo, Jihye Park, Mijin Kwon, Young Bin Park, Jae‐Mun Choi, Seung‐Ho Lee, Sangho Roh   +8 more
wiley   +1 more source

A scoping review on the implementation dynamics of scaling up a community-based health promotion and exercise program for older adults: opportunities and challenges. [PDF]

BMC Public Health
Segar SG, Whitney J, Singh DKA.
europepmc   +1 more source

Tumor mutational burden as a determinant of metastatic dissemination patterns

Molecular Oncology, EarlyView.
This study performed a comprehensive analysis of genomic data to elucidate whether metastasis in certain organs share genetic characteristics regardless of cancer type. No robust mutational patterns were identified across different metastatic locations and cancer types.
Eduardo Candeal, Andrea Moreno‐Manuel, Miguel Salvadó‐Pertierra, Cristina Santos‐Vivas, Rebeca Sanz‐Pamplona   +4 more
wiley   +1 more source

The challenges of scaling-up

Bulletin of the World Health Organization, 2007
Andy Haines, Sharon Huttly
doaj  

Assessing the economic cost of road traffic crashes in Saudi Arabia: potential savings from scaling up interventions. [PDF]

Front Public Health
Spencer G, Alluhidan M, Reithinger R, Alsukait RF, Czapski R, Alamri A, Cetinkaya V, Alshehri F, Dahdah S, Hamza MM, Herbst CH, Alghnam S.   +11 more
europepmc   +1 more source

Targeting p38α in cancer: challenges, opportunities, and emerging strategies

Molecular Oncology, EarlyView.
p38α normally regulates cellular stress responses and homeostasis and suppresses malignant transformation. In cancer, however, p38α is co‐opted to drive context‐dependent proliferation and dissemination. p38α also supports key functions in cells of the tumor microenvironment, including fibroblasts, myeloid cells, and T lymphocytes.
Angel R. Nebreda
wiley   +1 more source