Results 241 to 250 of about 1,653,695 (312)

Early experience scaling up a breast cancer early detection initiative integrated with cervical cancer screening in Rwanda. [PDF]

BMJ Glob Health
Pace LE, Uwihaye JD, Mukandayisenga V, Fata AM, Rositch AF, Byiringiro J, Nyinawabega J, Gaju S, Dusengimana JMV, Rugema V, Maniragaba T, Hagenimana M, Uwinkindi F, Cubaka V.   +13 more
europepmc   +1 more source

Correlation of the differential expression of PIK3R1 and its spliced variant, p55α, in pan‐cancer

Molecular Oncology, EarlyView.
PIK3R1 undergoes alternative splicing to generate the isoforms, p85α and p55α. By combining large patient datasets with laboratory experiments, we show that PIK3R1 spliced variants shape cancer behavior. While tumors lose the protective p85α isoform, p55α is overexpressed, changes linked to poorer survival and more pronounced in African American ...
Ishita Gupta, Yang Song, Madeleine Ndahayo, Anirudh Saxena, Theresa Guo, Dylan Z. Kelley, Jessica Gore, Andrew Hennigan, Alexa Anderson, John C. Papadimitriou, Daria A. Gaykalova   +10 more
wiley   +1 more source

Scaling up the sono-enzymatic coating of cotton textiles with antimicrobial silver-phenolated lignin nanocomposites. [PDF]

Ultrason Sonochem
Rathee G, Blair J, Puertas-Segura A, Ivanova K, Cabanes GF, Tzanov T.   +5 more
europepmc   +1 more source

Tumour–host interactions in Drosophila: mechanisms in the tumour micro‐ and macroenvironment

Molecular Oncology, EarlyView.
This review examines how tumour–host crosstalk takes place at multiple levels of biological organisation, from local cell competition and immune crosstalk to organism‐wide metabolic and physiological collapse. Here, we integrate findings from Drosophila melanogaster studies that reveal conserved mechanisms through which tumours hijack host systems to ...
José Teles‐Reis, Tor Erik Rusten
wiley   +1 more source

Basroparib inhibits YAP‐driven cancers by stabilizing angiomotin

Molecular Oncology, EarlyView.
Basroparib, a selective tankyrase inhibitor, suppresses Wnt signaling and attenuates YAP‐driven oncogenic programs by stabilizing angiomotin. It promotes AMOT–YAP complex formation, enforces cytoplasmic YAP sequestration, inhibits YAP/TEAD transcription, and sensitizes YAP‐active cancers, including KRAS‐mutant colorectal cancer, to MEK inhibition.
Young‐Ju Kwon, Dong Young Kim, Yuna Kim, Uk‐Il Kim, Jae‐Sung Kim   +4 more
wiley   +1 more source

Value of a Nationwide University Network in scaling up telemonitoring: a qualitative study. [PDF]

BMJ Health Care Inform
Gijsbers HJH, Nurmohamed SA, Dusseljee-Peute LW, Schijven MP, van de Belt TH, Citrien 2.   +5 more
europepmc   +1 more source

RaMBat: Accurate identification of medulloblastoma subtypes from diverse data sources with severe batch effects

Molecular Oncology, EarlyView.
To integrate multiple transcriptomics data with severe batch effects for identifying MB subtypes, we developed a novel and accurate computational method named RaMBat, which leveraged subtype‐specific gene expression ranking information instead of absolute gene expression levels to address batch effects of diverse data sources.
Mengtao Sun, Jieqiong Wang, Shibiao Wan
wiley   +1 more source

Challenges in scaling up a perfusion process

BMC Proceedings, 2011
Raja Vana, Desan Saravanan, Bhatnagar Ankur, Goel Anuj, Iyer Harish   +4 more
doaj   +1 more source

Recent Advances in Scaling up Bioelectrochemical Systems: A Review. [PDF]

BioTech (Basel)
Corona-Martínez DA, Martínez-Amador SY, Rodríguez-De la Garza JA, Laredo-Alcalá EI, Pérez-Rodríguez P.   +4 more
europepmc   +1 more source

Actin dynamics controlled by IqgC, a RasGAP at the crossroads between the IQGAP and fungal GAP1 families

FEBS Open Bio, EarlyView.
IqgC is a RasGAP from Dictyostelium discoideum. IqgC binds RasG via its RasGAP domain and deactivates it on macroendocytic cups, thereby suppressing the uptake of fluid and particles. IqgC has a positive effect on cell‐substratum adhesion, and its RGCt domain is required for recruitment to ventral foci.
Vedrana Filić, Darija Putar, Lucija Mijanović, Igor Weber   +3 more
wiley   +1 more source