Results 261 to 270 of about 14,169,777 (290)

On subcellular distribution of the zinc finger 469 protein (ZNF469) and observed discrepancy in the localization of endogenous and overexpressed ZNF469

FEBS Open Bio, EarlyView.
ZNF469 regulates the expression of genes encoding extracellular matrix proteins. Endogenous ZNF469 is predominantly cytoplasmic, while in transfected cells, it forms aggregates reminiscent of biomolecular condensates, located mainly in the nucleus. These condensates exhibit overlapping staining with proteasomes and are also associated with the mitotic ...
Anne Elisabeth Christensen Mellgren, Ileana Cristea, Thomas Stevenson, Endy Spriet, Per Morten Knappskog, Stig Ove Bøe, Harald Kranz, Sushma N. Grellscheid, Eyvind Rødahl   +8 more
wiley   +1 more source

Impact of scaling up health intervention coverage on reducing maternal mortality in 26 low- and middle-income countries: A modelling study. [PDF]

J Glob Health
Guo XR, Ji YL, Yan SY, Shi T, Chamroonsawasdi K, Liu J, Wang HJ.   +6 more
europepmc   +1 more source

Advanced glycation end products promote the release of endothelial cell‐derived mitocytosis

FEBS Open Bio, EarlyView.
Under diabetic conditions, AGEs induce mitochondrial damage in HUVECs, activating migrasome‐mediated mitocytosis. Migrasomes encapsulate damaged mitochondria and are released into the extracellular space, facilitating intercellular mitochondrial transfer.
Rong Liu, Yuhao Zhang, Tiantian Ge, Hao Wu, Yongbin Ma, Honghua Ye, Fei Guo   +6 more
wiley   +1 more source

Mind the Gap: scaling-up access to culturally adapted mental health treatments for minority populations. [PDF]

BMC Glob Public Health
Molander O, Särnholm J, Hollander AC, Jayaram-Lindström N.   +3 more
europepmc   +1 more source

KCS1 and VIP1, the genes encoding yeast phosphoinositol pyrophosphate synthases, are required for Ca2+‐mediated response to dimethylsulfoxide (DMSO)

FEBS Open Bio, EarlyView.
Ca2+‐mediated response to DMSO was investigated in Saccharomyces cerevisiae cells expressing Ca2+‐dependent aequorin. Cell exposure to DMSO induced a cytosolic Ca2+ wave dependent on the integrity of the Cch1/Mid1 channel. Deletion of KCS1 or VIP1 genes encoding the phosphoinositol pyrophosphate (PP‐IP) synthases suppressed the DMSO‐induced Ca2 ...
Larisa Ioana Gogianu, Lavinia Liliana Ruta, Claudia Valentina Popa, Simona Ghenea, Ileana Cornelia Farcasanu   +4 more
wiley   +1 more source

Ethiopian primary healthcare clinical guidelines 5 years on-processes and lessons learnt from scaling up a primary healthcare initiative. [PDF]

BMJ Glob Health
Kibret AG, Belete WM, Hanlon C, Ataro I, Tsegaye K, Tadesse Z, Feleke M, Abdella M, Wale M, Befekadu K, Bekele A, Georgeu-Pepper D, Ras CJ, Fairall LR, Cornick RV.   +14 more
europepmc   +1 more source

Long non‐coding RNAs as therapeutic targets in head and neck squamous cell carcinoma and clinical application

FEBS Open Bio, EarlyView.
Long non‐coding RNAs (lncRNAs) occupy an abundant fraction of the eukaryotic transcriptome and an emerging area in cancer research. Regulation by lncRNAs is based on their subcellular localization in HNSCC. This cartoon shows the various functions of lncRNAs in HNSCC discussed in this review.
Ellen T. Tran, Ruchi A. Patel, Amogh Chariyamane, Ratna B. Ray   +3 more
wiley   +1 more source

Moving forward: scaling-up the integration of an HIV and hypertension program in Akwa Ibom State, Nigeria. [PDF]

Glob Health Res Policy
Mishra S, Aifah AA, Henry D, Uzoigwe N, Udoh EB, Idang E, Munagala J, Onakomaiya D, Kanneh N, Ekanem A, Attah EA, Ogedegbe G, Ojji D.   +12 more
europepmc   +1 more source

Matrigel inhibits elongation and drives endoderm differentiation in aggregates of mouse embryonic stem cells

FEBS Open Bio, EarlyView.
Stem cell‐based embryo models (SCBEMs) are valuable to study early developmental milestones. Matrigel, a basement membrane matrix, is a critical substrate used in various SCBEM protocols, but its role in driving stem cell lineage commitment is not clearly defined.
Atoosa Amel, Rachel Brown, Alexa Rabeling, Mubeen Goolam   +3 more
wiley   +1 more source

Scaling up multispectral color filters with binary lithography and reflow (BLR). [PDF]

Nanophotonics
Rahman MA, Rezaei SD, Arora D, Wang H, Mori T, Chia SC, Chan JYE, Nair PNS, Uddin S, Pan CF, Zhang W, Wang H, Ruitao Z, Heng LS, Yang JKW.   +14 more
europepmc   +1 more source