Results 41 to 50 of about 14,169,777 (290)

Rapid Scaling Up of Covid-19 Diagnostic Testing in the United States — The NIH RADx Initiative

New England Journal of Medicine, 2020
RADx — Rapid Scaling Up of Covid-19 Testing In April 2020, Congress appropriated $1.5 billion to the NIH to increase national testing capacity for SARS-CoV-2.
B. Tromberg, Tara A. Schwetz, E. Perez-stable, R. Hodes, R. Woychik, R. Bright, R. Fleurence, F. S. Collins   +7 more
semanticscholar   +1 more source

Scaling‐up biodiversity‐ecosystem functioning research

Ecology Letters, 2020
A rich body of knowledge links biodiversity to ecosystem functioning (BEF), but it is primarily focused on small scales. We review the current theory and identify six expectations for scale dependence in the BEF relationship: (1) a nonlinear change in ...
Andrew Gonzalez, R. Germain, D. Srivastava, É. Filotas, L. Dee, D. Gravel, Patrick L. Thompson, F. Isbell, Shaopeng Wang, S. Kéfi, J. Montoya, Yuval R. Zelnik, M. Loreau   +12 more
semanticscholar   +1 more source

Prevention and treatment of acute malnutrition in humanitarian emergencies: a multi-organisation collaboration to increase access to synthesised evidence

Journal of International Humanitarian Action, 2019
Background Program decision-making to prevent and treat acute malnutrition in an emergency can be hampered by a lack of accessible and relevant overviews of directly available robust research evidence.
Claire Allen, Jeroen Jansen, Celeste Naude, Solange Durao, Monaz Mehta, Erik von Elm, Saskia van der Kam, Claudine Prudhon, Amy Mayberry, Marie McGrath, Carmelia Alae-Carew, James A. Berkley, Patrizia Fracassi, Nancy Aburto, Mica Jenkins, Jessica Bourdaire, Shona Lang, Alex Nevitte, Isla Kuhn, Shaun Lee, Hannah Hafezi   +20 more
doaj   +1 more source

Health information use and the associated factors among public health facilities of the Sidama Zone, southern Ethiopia: a facility-based cross-sectional study

Healthcare in Low-resource Settings
A strong Health Information System (HIS) is a foundation for evidence-based decision making in health care management. However, there is a dearth of literature with respect to health information use practice, particularly in public health facilities of ...
Melaku Getahun, Keneni Gutema Negeri
doaj   +1 more source

Challenges of Scaling Up SARS-CoV-2 Rapid Antigen Tests

Annals of Clinical Microbiology, 2021
The current reference standard for the diagnosis of coronavirus disease 2019 (COVID-19) is the molecular detection of severe acute respiratory syndrome coronavirus-2 (SARS-CoV-2). Several rapid antigen tests (RATs) have been developed for the rapid and
Mi-Kyung Lee
doaj   +1 more source

Elucidation of interface interactions between a dehydratase domain and an acyl carrier protein in cremimycin polyketide synthase

FEBS Letters, EarlyView.
In modular polyketide synthases, the dehydratase (DH) domain catalyzes the dehydration reaction of the β‐hydroxyacyl unit attached to the cognate acyl carrier protein (ACP) domain. However, it is unclear how DH interacts with ACP during the reaction. In this study, we identified DH–ACP interface residues, providing the first detailed insights into DH ...
Kaede Kotagiri, Haruka Tachibana, Daisuke Kawasaki, Taichi Chisuga, Toma Kashima, Shinya Fushinobu, Fumitaka Kudo, Tadashi Eguchi, Akimasa Miyanaga   +8 more
wiley   +1 more source

Are boys more vulnerable to stunting? Examining risk factors, differential sensitivity, and measurement issues in Zambian infants and young children

BMC Public Health
Background Stunting remains a considerable public health problem globally, and sex differences in prevalence have been documented. While many risk factors for stunting have been identified, few studies examine how these factors may contribute to sex ...
Amanda L. Thompson, Mathews Onyango, Patricia Sakala, John Manda, Edna Berhane, Mary Pat Selvaggio, Agnes Aongola, Stephanie L. Martin   +7 more
doaj   +1 more source

Social enterprise scaling up strategy – franchise development

Studia i Materiały, 2018
This paper is an exploratory study on the essence of social franchise as a business model and form of entrepreneurship and study how to use the proven business model to satisfy social needs.
Marta Ziółkowska
doaj   +1 more source

Functional variation among LPMOs revealed by the inhibitory effects of cyanide and buffer ions

FEBS Letters, EarlyView.
This study addresses the inhibition of lytic polysaccharide monooxygenases (LPMOs) by cyanide and explains how and why the magnitude of observed inhibitory effects depends on the way LPMO reactions are setup and on the type of LPMO. Enzymes known as lytic polysaccharide monooxygenases (LPMOs) are mono‐copper polysaccharide‐degrading peroxygenases that ...
Ole Golten, Lorenz Schwaiger, Zarah Forsberg, Kelsi R. Hall, Anton A. Stepnov, Tom Z. Emrich‐Mills, Iván Ayuso‐Fernández, Morten Sørlie, Roland Ludwig, Åsmund Kjendseth Røhr, Vincent G. H. Eijsink   +10 more
wiley   +1 more source

Ablation of LRP6 in alpha‐smooth muscle actin‐expressing cells abrogates lung inflammation and fibrosis upon bleomycin‐induced lung injury

FEBS Letters, EarlyView.
Low‐density lipoprotein receptor‐related protein 6 (LRP6) is a key receptor for the Wnt antagonist Dickkopf1 (DKK1). DKK1 protein expression is induced in a bleomycin (BLM)‐induced lung injury model. We show that DKK1 induces proinflammatory and profibrotic genes in lung fibroblasts.
Eun‐Ah Sung, Mikhail G. Dozmorov, SuJeong Song, Theingi Aung, Min Hee Park, Patricia J. Sime, Wook‐Jin Chae   +6 more
wiley   +1 more source