Results 71 to 80 of about 1,653,695 (312)
A Funder Journey: Scaling Up the Stone Family Foundation [PDF]
, 2012 This report follows the journey of one foundation from its inception to the present day. It highlights the work of an effective funder, and shares lessons that can be applied to funding more widely.
core
Matrix Model Calculations beyond the Spherical Limit
, 1993 We propose an improved iterative scheme for calculating higher genus contributions to the multi-loop (or multi-point) correlators and the partition function of the hermitian one matrix model. We present explicit results up to genus two.
Ambjørn, J. +3 more
core +1 more source
Exposure of commercially exploited shellfish to changing pH levels: how to scale-up experimental evidence to regional impacts [PDF]
, 2022 Bryony L. Townhill +3 more
openalex +1 more source
FEBS Letters, EarlyView.In this study, we present the structure of AcrIE8.1, a previously uncharacterized anti‐CRISPR protein that inhibits the type I‐E CRISPR‐Cas system. Through a combination of structural and biochemical analyses, we demonstrate that AcrIE8.1 directly binds to the Cas11 subunit of the Cascade complex to inhibit the CRISPR‐Cas system.
Young Woo Kang, Hyun Ho Park
wiley +1 more source
Scaling-up Empirical Risk Minimization: Optimization of Incomplete U-statistics [PDF]
, 2016 In a wide range of statistical learning problems such as ranking, clustering or metric learning among others, the risk is accurately estimated by $U$-statistics of degree $d\geq 1$, i.e.
Bellet, Aurélien +2 more
core +2 more sources
An intracellular transporter mitigates the CO2‐induced decline in iron content in Arabidopsis shoots
FEBS Letters, EarlyView.This study identifies a gene encoding a transmembrane protein, MIC, which contributes to the reduction of shoot Fe content observed in plants under elevated CO2. MIC is a putative Fe transporter localized to the Golgi and endosomal compartments. Its post‐translational regulation in roots may represent a potential target for improving plant nutrition ...
Timothy Mozzanino +7 more
wiley +1 more source
Hematopoietic (stem) cells—The elixir of life?
FEBS Letters, EarlyView.The aging of HSCs (hematopoietic stem cells) and the blood system leads to the decline of other organs. Rejuvenating aged HSCs improves the function of the blood system, slowing the aging of the heart, kidney, brain, and liver, and the occurrence of age‐related diseases.
Emilie L. Cerezo +4 more
wiley +1 more source
Obtaining Self-similar Scalings in Focusing Flows
, 2015 The surface structure of converging thin fluid films displays self-similar behavior, as was shown in the work by Diez et al [Q. Appl. Math 210, 155, 1990].
Behringer, Robert P. +4 more
core +3 more sources
FEBS Letters, EarlyView.This perspective highlights emerging insights into how the circadian transcription factor CLOCK:BMAL1 regulates chromatin architecture, cooperates with other transcription factors, and coordinates enhancer dynamics. We propose an updated framework for how circadian transcription factors operate within dynamic and multifactorial chromatin landscapes ...
Xinyu Y. Nie, Jerome S. Menet
wiley +1 more source