Results 51 to 60 of about 2,992 (150)

Dermatologic Toxicities Associated With Novel Pan‐RAS/RAF Inhibitors

Journal of Cutaneous Pathology, EarlyView.
ABSTRACT Background The mitogen‐activated protein kinase (MAPK) pathway plays a key role in cell‐cycle regulation and tumor progression in cancer. Dermatologic toxicities (DTs) to newer pan‐RAS (RMC‐6236) and pan‐RAF (LXH254/naporafenib) inhibitors are emerging.
Lin J. He, Shaymaa Hegazy, Phyu P. Aung, Priyadharsini Nagarajan, Fiorinda Muhaj, Adrienne N. Choksi, Ana M. Ciurea, Kelly C. Nelson, Doina Ivan, Carlos A. Torres‐ Cabala, Victor G. Prieto, Jonathan L. Curry   +11 more
wiley   +1 more source

Prurigo Pigmentosa – an increasingly diagnosed dermatological condition associated with ketogenic diet

JDDG: Journal der Deutschen Dermatologischen Gesellschaft, EarlyView.
SUMMARY Prurigo pigmentosa (PP) is a rare inflammatory dermatosis, clinically characterized by intensely pruritic, erythematous papules and papulovesicles, with reticular hyperpigmentation upon healing. We herein report four cases in adults of different ethnic backgrounds, in which the disease was associated with ketogenic metabolic states due to ...
Antigona Aliu, Milan Vidakovic, Marcel Krauß, Julia Hyun, Frank Oellig, Thilo Gambichler, Valentina Laura Müller, Alexander Kreuter   +7 more
wiley   +1 more source

Clinical improvement and scalp microbiome restructuring following a 28‐day piroctone olamine shampoo intervention

International Journal of Cosmetic Science, EarlyView.
A 28‐day clinical study in 41 individuals with oily dandruff showed that a piroctone olamine shampoo improved clinical symptoms while selectively reshaping the scalp bacterial and fungal microbiome toward a less dysbiotic profile. Abstract Objective To evaluate the clinical efficacy of a piroctone olamine–containing shampoo in individuals with oily ...
Spyridon Markos, Lina Praefke, Yiannis Kapetanstatakis, Michail Tsanakas, Evangelos Beletsiotis   +4 more
wiley   +1 more source

Angiosarcoma of the scalp in the elderly: a case series

Journal of the Egyptian Women’s Dermatologic Society
Cutaneous angiosarcoma (AS) is a rare soft tissue malignancy that often mimics various dermatoses, leading to a delay in diagnosis. The rapid rate of progression portends a poor prognosis.
Carol Lobo, Prathibha J.P, Shubha Bhagavan, Vivek M. Pai   +3 more
doaj   +1 more source

Papulosquamous scalp dermatoses: key aspects of differential diagnosis and treatment

Meditsinskiy sovet = Medical Council
Psoriasis and seborrheic dermatitis are common papulosquamous dermatoses. When localized only on the scalp, they often have very similar clinical manifestations and require a comprehensive differential diagnostic approach. The article presents the main comparative clinical and diagnostic characteristics of psoriasis and seborrheic dermatitis of the ...
G. P. Tereshchenko, O. V. Zhukova, M. N. Ostretsova, M. A. Bobrov, S. Alhaffar   +4 more
openaire   +1 more source

PDE4 Inhibition in Dermatologic Disease: Impacts Beyond Inflammation

International Journal of Dermatology, EarlyView.
This graphical abstract demonstrates the comprehensive mechanism of PDE4 inhibition in skin physiology. By increasing intracellular cAMP and activating PKA, PDE4 inhibitors exert pleiotropic effects, including immune modulation, pigmentation regulation, barrier enhancement, sensory neuron modulation, and improved wound healing with reduced fibrosis ...
Keana Khodadad, Nicole E. Chin, Raj Chovatiya   +2 more
wiley   +1 more source

Nodular Secondary Syphilis: Systematic Review of an Underrecognized Clinical Phenotype

International Journal of Dermatology, EarlyView.
Nodular secondary syphilis is a rare and often misdiagnosed manifestation of secondary syphilis with diverse clinical and histopathologic features. This systematic review of 144 cases highlights its frequent association with ulceration, generalized skin involvement, and HIV infection, emphasizing the importance of considering syphilis in the ...
Jacopo Tartaglia, Monica Ponzano, Alvise Sernicola, Roberto Mazzetto, Mauro Alaibac   +4 more
wiley   +1 more source

Dermoscopic findings in scalp psoriasis and seborrheic dermatitis; Two new signs; Signet ring vessel and hidden hair

Indian Journal of Dermatology, 2015
Background: Psoriasis and seborrheic dermatitis are both chronic erythemato-squamous dermatoses that can involve the scalp. It may be difficult to differentiate these two diseases when there is isolated scalp involvement.
Melike Kibar, Şebnem Aktan, Muzaffer Bilgin   +2 more
doaj   +1 more source

Ulceronecrotic Plaques, Patchy Scalp Alopecia and Visual Disturbance in a 46‐Year‐Old Man

International Journal of Dermatology, EarlyView.
ABSTRACT A 46‐year‐old incarcerated man with chronic hepatitis C infection and intravenous drug use presented with a rapidly progressive pruritic eruption involving the scalp, trunk, and limbs, accompanied by patchy scalp alopecia and bilateral panuveitis.
Alex Majri, Austen Anderson, Jeremy Ng, Nima Mesbah‐Ardakani   +3 more
wiley   +1 more source

Dermatology in black skin

Anais Brasileiros de Dermatologia
The vast majority of publications in dermatology refer to lightly pigmented skin, with few addressing the peculiarities of black skin. In addition there is no consensus on what it means to be black in different regions of the world. The lack of knowledge
Maurício Mota de Avelar Alchorne, Katleen da Cruz Conceição, Leonardo Lora Barraza, Marilda Aparecida Milanez Morgado de Abreu   +3 more
doaj   +1 more source