Results 71 to 80 of about 2,842 (190)

Cancer‐Associated BCL‐2 Mutants Reveal Mechanisms Towards Venetoclax Resistance

open access: yesAdvanced Science, EarlyView.
Venetoclax (VEN) resistance in chronic lymphocytic leukemia arises from diverse BCL2 mutations. We map mechanisms contributing to VEN resistance across common BCL‐2 variants. G101V and D103Y reduce drug binding and increase sequestration of pro‐apoptotic proteins. V156D blocks VEN allosterically.
Jonas Aufdermauer   +9 more
wiley   +1 more source

Semantic segmentation through Artificial Intelligence from raw point clouds to H-BIM representation

open access: yesDisegnare con, 2023
This work describes a semi automatic workflow for the 3D reconstruction of Heritage Building Information Models from raw point clouds, based on Artificial Intelligence techniques. The BIM technology applied to historical architecture has made it possible
Lorenzo Ceccarelli   +4 more
doaj  

Scanning Technologies to Building Information Modelling: A Review

open access: yesInfrastructures, 2022
Building information modelling (BIM) is evolving significantly in the architecture, engineering and construction industries. BIM involves various remote-sensing tools, procedures and standards that are useful for collating the semantic information ...
Rabia Rashdi   +3 more
doaj   +1 more source

Unraveling G‐Quadruplex and i‐Motif Coexistence Within a Double‐Stranded DNA

open access: yesAngewandte Chemie, Volume 138, Issue 31, 27 July 2026.
The relative thermodynamic profiles of G‐quadruplex (G4), i‐Motif (iM), and the duplex counterpart tune the simultaneous G4 and iM formation within a double‐stranded (ds) DNA. ABSTRACT DNA can transiently fold into variable arrangements, which are expected to exploit regulatory functions. Guanine‐rich sequences can fold into G‐quadruplexes (G4s), while
Davide Auricchio   +7 more
wiley   +2 more sources

How to Navigate Disrupted Business Models in the 21st Century: At the Crossroads of the Circular Economy and the Industry 4.0 Transition

open access: yesBusiness Strategy and the Environment, EarlyView.
ABSTRACT Our planet faces a critical crisis, with pollution, resource depletion and biodiversity loss surpassing sustainable limits. Businesses must address these challenges, with the circular economy and Industry 4.0 offering transformative potential through closed‐loop systems, regenerative solutions and advanced technologies.
Agnes Toth‐Peter   +3 more
wiley   +1 more source

Dalla nuvola di punti al modello BIM : metodo semi-automatico per il rilevamento delle componenti opache. Caso studio: Villa Aletti - Spartivento a Varese [PDF]

open access: yes, 2022
LAUREA MAGISTRALENel settore delle costruzioni l’introduzione di tecniche di rilievo 3D sempre più avanzate, come il laser scanner e la fotogrammetria, ha consentito di ottenere in tempi sempre minori e con una precisione sempre maggiore il dato ...
Maffi, Andrea
core  

Tecniche di rilievo integrato per processi Scan-to-BIM

open access: yesGEOmedia, 2022
The preservation of historic buildings can often be particularly difficult due to the lack of detailed information about architectural features, construction details, etc.
Mauro Lo Brutto
doaj  

Object verification based on deep learning point feature comparison for scan-to-BIM [PDF]

open access: yes, 2022
Building information models (BIMs) have been widely adopted in current construction projects to enhance the efficiency of facility maintenance operations.
Cheng, Jack C.P.   +7 more
core   +1 more source

Business and Governance Strategies for Circular Economy Valorization of Construction Timber: A Systematic Review

open access: yesBusiness Strategy and the Environment, EarlyView.
ABSTRACT The valorization of construction and demolition timber is essential to advancing circular economy objectives but remains constrained by fragmented organizational, network, and institutional practices. For firms in the construction sector, this represents a critical strategic adaptation challenge.
Reeko Watanabe   +6 more
wiley   +1 more source

Study on Representative Parameters of Reverse Engineering for Maintenance of Ballasted Tracks

open access: yesApplied Sciences, 2022
Reverse engineering (RE) is a technology used to create three-dimensional (3D) models by scanning structures and can be used to examine the current condition of structures.
Suyeul Park, Seok Kim, Heechang Seo
doaj   +1 more source

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