Results 71 to 80 of about 38,704 (246)

Inflammatory myofibroblastic tumor of the pancreatic head

Journal of the Belgian Society of Radiology, 2012
Inflammatory myofibroblastic tumors are rare, especially in the pancreas. It is sometimes difficult to obtain a definitive diagnosis with radiological imaging and there is not yet consensus about treatment.
L Lacoste, Ch Galant, J F Gigot, B Lacoste, L Annet   +4 more
doaj   +1 more source

Engineered Exosomal miR‐146a‐5p Reprograms BMSC Fate and Restores Mitochondrial Homeostasis in Glucocorticoid‐Induced Osteonecrosis of Femoral Head

Advanced Science, EarlyView.
Exosomal miR‐146a‐5p is identified as a pivotal regulator in steroid‐induced osteonecrosis. Its reduction activates NF‐κB signaling, compromises mitophagy, and disrupts mitochondrial bioenergetics, resulting in autophagic disequilibrium. Engineered exosomes delivering miR‐146a‐5p reinstate mitochondrial function, augment oxidative phosphorylation and ...
Zehui Lv, Xuejie Cai, Yiming Xu, Xingdong Yang, Ruoying Wang, Han Wang, Yixin Bian, Jiawei Xu, Jiao Lu, Lulu Liu, Yingjie Wang, Jibin Song, Bin Feng, Xisheng Weng   +13 more
wiley   +1 more source

Association of abdominal obesity with lumbar disc degeneration--a magnetic resonance imaging study.

PLoS ONE, 2013
PurposeTo evaluate whether midsagittal (abdominal) obesity in magnetic resonance imaging (MRI), waist circumference (WC) and body fat percentage are associated with lumbar disc degeneration in early adulthood.MethodsWe obtained the lumbar MRI (1.5-T ...
Jani Takatalo, Jaro Karppinen, Simo Taimela, Jaakko Niinimäki, Jaana Laitinen, Roberto Blanco Sequeiros, Dino Samartzis, Raija Korpelainen, Simo Näyhä, Jouko Remes, Osmo Tervonen   +10 more
doaj   +1 more source

Intensity Correction Method Customized for Multi-animal Abdominal MR Imaging with 3T Clinical Scanner and Multi-Array Coil

Magnetic Resonance in Medical Sciences, 2013
Simultaneous magnetic resonance (MR) imaging of multiple small animals in a single session increases throughput of preclinical imaging experiments. Such imaging using a 3-tesla clinical scanner with multi-array coil requires correction of intensity variation caused by the inhomogeneous sensitivity profile of the coil.
MITSUDA, Minoru, YAMAGUCHI, Masayuki, NAKAGAMI, Ryutaro, FURUTA, Toshihiro, SEKINE, Norio, NIITSU, Mamoru, MORIYAMA, Noriyuki, FUJII, Hirofumi   +7 more
openaire   +3 more sources

A Foundation Model Based CT Biomarker for Non‐Invasive Prediction of Response to Neoadjuvant Immunochemotherapy in Non‐Small Cell Lung Cancer

Advanced Science, EarlyView.
This study introduces a foundation model‐based biomarker for risk stratification of pathological response in non‐small cell lung cancer. A Vision Mamba super‐resolution model standardizes heterogeneous CT images. A multi‐task Swin Transformer then fine‐tunes a pre‐trained lung foundation model to jointly optimize tumor segmentation and response ...
Yanglan Xu, Shuchang Zhou, Qin Peng, Xiao Bao, Xiaodan Ye, Ahmet Görkem Er, Tong Tong, Mirabela Rusu, Yajia Gu, Mailin Chen, Jing Gong   +10 more
wiley   +1 more source

The Regeneration Potential after Human and Autologous Stem Cell Transplantation in a Rat Sciatic Nerve Injury Model can be Monitored by MRI

Cell Transplantation, 2015
Traumatic nerve injuries are a major clinical challenge. Tissue engineering using a combination of nerve conduits and cell-based therapies represents a promising approach to nerve repair. The aim of this study was to examine the regeneration potential of
Mathias Tremp, Moritz Meyer Zu Schwabedissen, Elisabeth A. Kappos, Patricia E. Engels, Arne Fischmann, Arnaud Scherberich, Dirk J. Schaefer, Daniel F. Kalbermatten M.D., Ph.D.   +7 more
doaj   +1 more source

Intrinsically Mitochondria‐Targeting Nanozyme via Coordination‐Assembly of Natural Quercetin for Cascade Antioxidant Therapy of Cerebral Ischemia‐Reperfusion Injury

Advanced Science, EarlyView.
This study uncovers that quercetin naturally targets mitochondria. By coordinating quercetin with Fe3+, we engineer an ultrasmall cascade nanozyme (MCN) with superoxide dismutase‐catalase activities. MCN crosses the damaged blood–brain barrier, scavenges mitochondrial ROS, prevents mitochondrial DNA leakage, and blocks the cGAS‐STING pathway, thereby ...
Wenxuan Zheng, Zhicheng Wang, Xin Zhou, Shuya Wang, Xiaojing Shi, Tingli Xiong, Ruishi Li, Yuting Lin, Zhen Chen, Jiawen Wei, Fei Li, Jinwen Ge, Kelong Ai, Chong Liu, Guiming Deng   +14 more
wiley   +1 more source

A large urachal cyst presenting with lower urinary tract symptoms and a falsely elevated post-void residual on bladder scan

Urology Case Reports
The urachus is an embryologic remnant that connects the bladder to the umbilicus and typically obliterates during gestation. Urachal cysts are one of the most common congenital urachal anomalies.
Dana-Leigh Thiesfeldt, Abhishek Seth, Pamela Ellsworth   +2 more
doaj   +1 more source

In vivo magnetic resonance imaging of mice liver tumors using a new gadolinium-based contrast agent

Kaohsiung Journal of Medical Sciences, 2013
We compared the enhancement effect between a newly synthesized tissue-specific contrast agent, [Gd-DOTA-FPβG], and a commercially available agent, [Gd(DOTA)]−, in a murine model of liver tumor using a clinical magnetic resonance imaging scanner.
Shih-Hsien Chen, Yu-Ting Kuo, Tian-Lu Cheng, Chiao-Yun Chen, Yen-Yu Chiu, Jui-Jen Lai, Chih-Ching Chang, Twei-Shiun Jaw, Yun-Ming Wang, Gin-Chung Liu   +9 more
doaj   +1 more source

Stiffness‐Activated Stellate Cells Drive Pancreatic Cancer Liver Colonization via GMFG‐TNS4 Signaling

Advanced Science, EarlyView.
Fibrotic liver stiffness activates hepatic stellate cells through Piezo1‐dependent calcium influx and ER stress, promoting EV‐associated GMFG release. Delivered GMFG engages TNS4 in pancreatic cancer cells, triggering FAK/AKT signaling, adhesion, and fatty acid synthesis.
Biwen Zhu, Jian Wan, Xue Zhang, Jiashuai Yan, Xi Chen, Xiaoqi Guan, Qianqian Ren, Tao Yang, Di Wu, Qingsong Guo, Yibing Guo, Yuhua Lu   +11 more
wiley   +1 more source