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Atomic force microscopy and other scanning probe microscopies
Current Opinion in Chemical Biology, 1998The highlight of the past year is the unfolding and refolding of the muscle protein titin in the atomic force microscope. A related highlight in the intersection between experiment and theory is a recent review of the effects of molecular forces on biochemical kinetics.
Helen, Hansma, Lía, Pietrasanta
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Combined scanning tunneling and force microscopy
Journal of Vacuum Science & Technology B: Microelectronics and Nanometer Structures Processing, Measurement, and Phenomena, 1994A combined scanning tunneling and force microscope (STM/FM) was built which allows for the simultaneous measurement of forces and force gradients along STM constant current contours. Measuring Au(111) surfaces with this combined STM/FM, very low tip–sample interaction forces and variations of the local stiffness (force gradient) in the vicinity of ...
Anselmetti, Dario +5 more
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Fast spiral-scan atomic force microscopy
Nanotechnology, 2009In this paper, we describe a new scanning technique for fast atomic force microscopy. In this method, the sample is scanned in a spiral pattern instead of the well established raster pattern. A spiral scan can be produced by applying single frequency cosine and sine signals with slowly varying amplitudes to the x-axis and y-axis of an atomic force ...
Mahmood, I. A., Moheimani, S. O. Reza
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Scanning force microscopy based amperometric biosensors
Analytical and Bioanalytical Chemistry, 2007Cantilever-based biosensing has developed into an important research area especially for biomedical and clinical analysis. In particular, the possibility to scan miniaturized amperometric biosensors with high-fidelity distance control across biomedically relevant sample surfaces enables the determination of pertinent analytes such as, e.g., adenosine 5′
Christine, Kranz, Justyna, Wiedemair
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Scanning Probe Microscopy: Ultrasonic Force and Scanning Kelvin Probe Force Microscopy
2004In 1981, Gerd Binning and Heinrich Rohree at IBM Zurich developed the first generation of the scanning probe microscope, the scanning tunneling microscope for which they received the Noble Prize in physics. The Scanning Tunneling Microscope (STM) was a fantastic breakthrough with its capability to image atoms with angstrom precision.
C. Druffner +4 more
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Scanning Force Microscopy (SFM)
1992The scanning tunneling microscope (STM) has revolutionized the field of microscopy. Even newer scanning microscopes are being developed which are based on piezoelectric transducers and sharp probing tips that scan a surface while a feedback loop regulates the distance between the probing tip and sample. In 1986 Binniget al.
E. Meyer, H. Heinzelmann
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Scanning force microscopy under aqueous solutions
Current Opinion in Structural Biology, 1997Merely ten years after its invention, the scanning force microscope is becoming a powerful method to investigate the structure and dynamics of biological molecules under aqueous environments. From the visualization of transcription in real time to the mechanical manipulation of individual proteins, the advances made during the past year open up a vast ...
BUSTAMANTE C. +2 more
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Normal and lateral forces in scanning force microscopy
Journal of Vacuum Science & Technology B: Microelectronics and Nanometer Structures Processing, Measurement, and Phenomena, 1994With an atomic force/friction force microscope operating in the constant force mode and with an optical lever technique as a deflection sensor, we have investigated the total force acting on the cantilever tip during the raster scanning of the sample surface. A model including the normal and lateral components of the force has been worked out.
ASCOLI C +7 more
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1994
Abstract Since its invention in 1982, scanning tunneling microscopy (STM) has enabled users to obtain images reflecting surface electronic structure with atomic resolution. This technology has proved indispensable as a characterization tool with applications in surface physics, chemistry, materials science, bio-science, and data storage ...
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Abstract Since its invention in 1982, scanning tunneling microscopy (STM) has enabled users to obtain images reflecting surface electronic structure with atomic resolution. This technology has proved indispensable as a characterization tool with applications in surface physics, chemistry, materials science, bio-science, and data storage ...
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