Results 61 to 70 of about 5,368 (222)

Simultaneous Confocal Scanning Laser Ophthalmoscopy Combined with High-Resolution Spectral-Domain Optical Coherence Tomography: A Review

Journal of Ophthalmology, 2011
We aimed to evaluate technical aspects and the clinical relevance of a simultaneous confocal scanning laser ophthalmoscope and a high-speed, high-resolution, spectral-domain optical coherence tomography (SDOCT) device for retinal imaging.
Verônica Castro Lima, Eduardo B. Rodrigues, Renata P. Nunes, Juliana F. Sallum, Michel E. Farah, Carsten H. Meyer   +5 more
doaj   +1 more source

MURIN: Multimodal Retinal Imaging and Navigated-laser-delivery for dynamic and longitudinal tracking of photodamage in murine models

Frontiers in Ophthalmology, 2023
IntroductionLaser-induced photodamage is a robust method for investigating retinal pathologies in small animals. However, aiming of the photocoagulation laser is often limited by manual alignment and lacks real-time feedback on lesion location and ...
Jose J. Rico-Jimenez, Joel Jovanovic, Joel Jovanovic, Joel Jovanovic, Stephanie L. Nolen, Joseph D. Malone, Gopikrishna M. Rao, Edward M. Levine, Edward M. Levine, Edward M. Levine, Yuankai K. Tao, Yuankai K. Tao, Yuankai K. Tao   +12 more
doaj   +1 more source

Characterization of retinal pigment epithelium layer in healthy and diseased retinas with high‐resolution adaptive optics transscleral flood illumination imaging

Acta Ophthalmologica, Volume 104, Issue 3, Page e277-e291, May 2026.
Abstract Purpose The retinal pigment epithelium (RPE) is critical in the pathophysiology of retinal diseases, such as age‐related macular degeneration. Adaptive optics transscleral flood illumination (AO‐TFI) offers rapid, detailed morphometric characterization of the RPE layer.
Leila Sara Eppenberger, Safa Mohanna, Sohrab Ferdowsi, Sonja Simon‐Zoula, Oliver Pfäffli, Christoph Amstutz, Lucas M. Bachmann, Michael A. Thiel, Martin K. Schmid   +8 more
wiley   +1 more source

Multi-modal and multi-scale clinical retinal imaging system with pupil and retinal tracking

Scientific Reports, 2022
We present a compact multi-modal and multi-scale retinal imaging instrument with an angiographic functional extension for clinical use. The system integrates scanning laser ophthalmoscopy (SLO), optical coherence tomography (OCT) and OCT angiography ...
Muhammad Faizan Shirazi, Jordi Andilla, Nicolas Lefaudeux, Claudia Valdes, Florian Schwarzhans, Marine Durand, Konstantinos Ntatsis, Danilo Andrade De Jesus, Luisa Sanchez Brea, Kiyoko Gocho, Josselin Gautier, Christina Eckmann-Hansen, Marie Elise Wistrup Torm, Abdullah Amini, Stefan Klein, Theo Van Walsum, Kate Grieve, Michel Paques, Michael Larsen, Pablo Loza-Alvarez, Xavier Levecq, Nicolas Chateau, Michael Pircher   +22 more
doaj   +1 more source

In vivo imaging reveals transient microglia recruitment and functional recovery of photoreceptor signaling after injury. [PDF]

, 2019
Microglia respond to damage and microenvironmental changes within the central nervous system by morphologically transforming and migrating to the lesion, but the real-time behavior of populations of these resident immune cells and the neurons they ...
Burns, Marie E, Ching, Karli, Miller, Eric B, Pugh, Edward N, Zhang, Pengfei   +4 more
core   +1 more source

Suprachoroidal and Subretinal Injections of AAV Using Transscleral Microneedles for Retinal Gene Delivery in Nonhuman Primates. [PDF]

, 2020
Retinal gene therapy using adeno-associated viruses (AAVs) is constrained by the mode of viral vector delivery. Intravitreal AAV injections are impeded by the internal limiting membrane barrier, while subretinal injections require invasive surgery and ...
Chung, Sook Hyun, Mollhoff, Iris N, Nguyen, Uyen Tu, Noronha, Glenn, Taraborelli, Donna, Thomasy, Sara M, Yiu, Glenn, Yoo, Jesse   +7 more
core  

Scanning laser ophthalmoscopy of choroidal neovascularisation using indocyanine green [PDF]

Australian and New Zealand Journal of Ophthalmology, 1995
Abstract Background: Choroidal neovascularisation is an important cause of visual loss in age‐related macular degeneration. Visualisation of these choroidal abnormalities with fluorescein angiography may be difficult, particularly if there is haemorrhage, excessive pigment, or excessive fluorescence.
K C, Tang, H A, Liu
openaire   +2 more sources

Dual‐Branch Deep Neural Network for FLIM Parameter Estimation

Advanced Photonics Research, Volume 7, Issue 4, April 2026.
A dual‐branch deep network combining an autoencoder and a CNN is developed for fit‐free estimation in FLIM data. The proposed model was shown to outperform fit‐based method and single‐branch CNN model of the same complexity. Fluorescence lifetime imaging microscopy (FLIM) is a powerful tool for studying molecular interactions and cellular ...
Mou Adhikari, Kathrin Groeneveld, Matthias Klemm, Ralf Mrowka, Jens Haueisen, Shuxia Guo, Thomas Bocklitz   +6 more
wiley   +1 more source

Retinal displacement after closure of idiopathic macular hole

Asian Pacific Journal of Tropical Medicine, 2018
Objective: To study the foveal displacement during the closure of idiopathic macular holes (MHs). Methods: Thirty-seven idiopathic MH patients treated by pars plana vitrectomy and internal limiting membrane peeling were studied prospectively.
Zhong-Cui Sun, Min Wang, Jia-Wen Fan, Ge-Zhi Xu   +3 more
doaj   +1 more source

Ultrawide field scanning laser ophthalmoscopy imaging of lipemia retinalis [PDF]

Acta Ophthalmologica, 2017
AbstractObjectiveTo describe the characteristic retinal features of lipemia retinalis when using ultrawide field scanning laser ophthalmoscopy.Main PointsWe report a case series of three subjects with ultrawide field retinal images showing cream discoloration of the fundus, light salmon‐coloured posterior retinal vessels and greyish pink peripheral ...
Paolo S, Silva, Aditi, Gupta, Radwan S, Ajlan, Deborah K, Schlossman, Ann M, Tolson, Jerry D, Cavallerano, Lloyd Paul, Aiello   +6 more
openaire   +2 more sources