Results 51 to 60 of about 1,136,091 (291)
ATF4‐mediated stress response as a therapeutic vulnerability in chordoma
Molecular Oncology, EarlyView.We screened 5 chordoma cell lines against 100+ inhibitors of epigenetic and metabolic pathways and kinases and identified halofuginone, a tRNA synthetase inhibitor. Mechanistically halofuginone induces an integrated stress response, with eIF2alpha phosphorylation, activation of ATF4 and its target genes CHOP, ASNS, INHBE leading to cell death ...
Lucia Cottone +11 more
wiley +1 more source
Inverse Obstacle Scattering Using Reduced Data [PDF]
SIAM Journal on Applied Mathematics, 1998 Summary: The classical result of Schiffer in acoustic scattering is that a knowledge of the far field pattern for all observation directions and all incident directions at a fixed wave number \(k\) uniquely determines the sound-soft scattering obstacle \(D\).
Kress, Rainer, Rundell, William
openaire +2 more sources
Plecstatin inhibits hepatocellular carcinoma tumorigenesis and invasion through cytolinker plectin
Molecular Oncology, EarlyView.The ruthenium‐based metallodrug plecstatin exerts its anticancer effect in hepatocellular carcinoma (HCC) primarily through selective targeting of plectin. By disrupting plectin‐mediated cytoskeletal organization, plecstatin inhibits anchorage‐dependent growth, cell polarization, and tumor cell dissemination.
Zuzana Outla +10 more
wiley +1 more source
An efficient algorithm for the large-scale smoothing of scattered data retrieved from remote sounding experiments [PDF]
Annales Geophysicae, 2003 We present a new algorithm for smoothing/interpolation of two-dimensional fields applicable to noisy data observed at scattered sites. The technique is based on a special statistics allowing one to simultaneously minimize the fit residual and the
D. Fussen
doaj +1 more source
Компьютерная оптика, 2023 A method of analytical study of a metal film perforated by cylindrical nanoholes as the basis of a metasurface has been proposed. The formulas deduced completely determine the electromagnetic field of a wave scattered by the hole at any distance from the
N.V. Selina
doaj +1 more source
Mapping of interstellar clouds with infrared light scattered from dust: TMC-1N [PDF]
, 2013 Mapping of near-infrared (NIR) scattered light is a recent method for the study of interstellar clouds, complementing other, more commonly used methods, like dust emission and extinction. Our goal is to study the usability of this method on larger scale,
Juvela, M. +3 more
core +1 more source
Molecular Oncology, EarlyView.Nanosecond infrared laser (NIRL) low‐volume sampling combined with shotgun lipidomics uncovers distinct lipidome alterations in oropharyngeal squamous cell carcinoma (OPSCC) of the palatine tonsil. Several lipid species consistently differentiate tumor from healthy tissue, highlighting their potential as diagnostic markers.
Leonard Kerkhoff +11 more
wiley +1 more source
, 2015 Studies of deep photometry of galaxies have presented discoveries of excess light in surface-brightness and colour profiles at large radii in the form of diffuse faint haloes and thick discs.
Sandin, Christer
core +1 more source
Super-Earths in the TW Hya disc [PDF]
, 2018 We test the hypothesis that the sub-millimetre thermal emission and scattered light gaps seen in recent observations of TW Hya are caused by planet-disc interactions.
Mentiplay, Daniel +2 more
core +2 more sources
\(C^{1}\) positive scattered data interpolation
Computers & Mathematics with Applications, 2010 zbMATH Open Web Interface contents unavailable due to conflicting licenses.
Hussain, Malik Zawwar, Hussain, Maria
openaire +1 more source