Results 61 to 70 of about 1,136,091 (291)
Peroxidasin enables melanoma immune escape by inhibiting natural killer cell cytotoxicity
Molecular Oncology, EarlyView.Peroxidasin (PXDN) is secreted by melanoma cells and binds the NK cell receptor NKG2D, thereby suppressing NK cell activation and cytotoxicity. PXDN depletion restores NKG2D signaling and enables effective NK cell–mediated melanoma killing. These findings identify PXDN as a previously unrecognized immune evasion factor and a potential target to improve
Hsu‐Min Sung +17 more
wiley +1 more source
, 2009 Light scattering techniques are widely used in many fields of condensed and sof t matter physics. Usually these methods are based on the study of the scattered light in the far field.
A. P. Philipse +30 more
core +1 more source
Near-field imaging of locally perturbed periodic surfaces [PDF]
, 2019 This paper concerns the inverse scattering problem to reconstruct a locally perturbed periodic surface. Different from scattering problems with quasi-periodic incident fields and periodic surfaces, the scattered fields are no longer quasi-periodic.
Liu, Xiaoli, Zhang, Ruming
core +3 more sources
Molecular Oncology, EarlyView.This study shows that copy number variations (CNVs) can be reliably detected in formalin‐fixed paraffin‐embedded (FFPE) solid cancer samples using ultra‐low‐pass whole‐genome sequencing, provided that key (pre)‐analytical parameters are optimized.
Hanne Goris +10 more
wiley +1 more source
Norm-Minimized Scattering Data from Intensity Spectra [PDF]
Mathematical Problems in Engineering, 2016 We apply thel1minimizing technique of compressive sensing (CS) to nonlinear quadratic observations. For the example of coherent X-ray scattering we provide the formulas for a Kalman filter approach to quadratic CS and show how to reconstruct the scattering data from their spatial intensity distribution.
Alexander Seel +3 more
openaire +3 more sources
Molecular Oncology, EarlyView.Aptamers are used both therapeutically and as targeting agents in cancer treatment. We developed an aptamer‐targeted PLGA–TRAIL nanosystem that exhibited superior therapeutic efficacy in NOD/SCID breast cancer models. This nanosystem represents a novel biotechnological drug candidate for suppressing resistance development in breast cancer.
Gulen Melike Demirbolat +8 more
wiley +1 more source
Candidate Coronagraphic Detections of Protoplanetary Disks around Four Young Stars
, 2009 We present potential detections of H-band scattered light emission around four young star, selected from a total sample of 45 young stars observed with the CIAO coronagraph of the Subaru telescope.
Andrews +37 more
core +1 more source
PERSISTENT SCATTERER INTERFEROMETRY USING SENTINEL-1 DATA [PDF]
The International Archives of the Photogrammetry, Remote Sensing and Spatial Information Sciences, 2016 Abstract. This paper is focused on deformation monitoring using a Persistent Scatterer Interferometry technique and the interferometric SAR data acquired by the Sentinel-1 satellite of the European Space Agency. The first part of the paper describes the procedure used to process and analyze Sentinel-1 interferometric SAR data.
M. Crosetto +5 more
openaire +4 more sources
RIPK4 function interferes with melanoma cell adhesion and metastasis
Molecular Oncology, EarlyView.RIPK4 promotes melanoma growth and spread. RIPK4 levels increase as skin lesions progress to melanoma. CRISPR/Cas9‐mediated deletion of RIPK4 causes melanoma cells to form less compact spheroids, reduces their migratory and invasive abilities and limits tumour growth and dissemination in mouse models.
Norbert Wronski +9 more
wiley +1 more source
Molecular Oncology, EarlyView.Cytarabine is a key therapy for acute myeloid leukaemia (AML), but its efficacy is limited by the dNTPase SAMHD1, which hydrolyses its active metabolite. Screening nucleotide biosynthesis inhibitors revealed that IMPDH inhibitors selectively sensitise SAMHD1‐proficient AML cells to cytarabine.
Miriam Yagüe‐Capilla +9 more
wiley +1 more source