Results 81 to 90 of about 1,136,091 (291)

Domain associated with zinc fingers‐containing NF90‐NF45 complex inhibits m6A modification of primary microRNA by suppressing METTL3/14 activity

FEBS Open Bio, EarlyView.
NF90–NF45 functions as a negative regulator of methyltransferase‐like 3/14 (METTL3/14)‐mediated N6‐methyladenosine (m6A) modification on primary microRNAs (pri‐miRNAs). NF90–NF45 binds to anti‐oncogenic pri‐miRNAs and inhibits their m6A modification, thereby suppressing the biogenesis of anti‐oncogenic miRNAs.
Takuma Higuchi, Shunsuke Morioka, Keiko Morisawa, Kazutsugu Matsukawa, Shingo Ashida, Takeshi Suzuki, Shuji Sakamoto   +6 more
wiley   +1 more source

Comparison of therapeutic dosimetric data from passively scattered proton and photon craniospinal irradiations for medulloblastoma

Radiation Oncology, 2012
Background For many decades, the standard of care radiotherapy regimen for medulloblastoma has been photon (megavoltage x-rays) craniospinal irradiation (CSI).
Howell Rebecca M, Giebeler Annelise, Koontz-Raisig Wendi, Mahajan Anita, Etzel Carol J, D’Amelio Anthony M, Homann Kenneth L, Newhauser Wayne D   +7 more
doaj   +1 more source

Scattered data fitting on surfaces using projected Powell-Sabin splines [PDF]

, 2007
We present C1 methods for either interpolating data or for fitting scattered data associated with a smooth function on a two-dimensional smooth manifold Ω embedded into R3. The methods are based on a local bivariate Powell-Sabin interpolation scheme, and
Davydov, Oleg, Schumaker, L.L.
core  

A schlieren method for ultra-low angle light scattering measurements

, 2003
We describe a self calibrating optical technique that allows to perform absolute measurements of scattering cross sections for the light scattered at extremely small angles.
A Vailati, Asnaghi Daniela, Brogioli D., Brogioli Doriano, D Brogioli, Domb Cyril, Giglio Marzio, Goodman J. W., M Giglio, Stanley H. E.   +9 more
core   +1 more source

Multi‐omics and low‐input proteomics profiling reveals dynamic regulation driving pluripotency initiation in early mouse embryos

FEBS Open Bio, EarlyView.
Mouse pre‐implantation development involves a transition from totipotency to pluripotency. Integrating transcriptomics, epigenetic profiling, low‐input proteomics and functional assays, we show that eight‐cell embryos retain residual totipotency features, whereas cytoskeletal remodeling regulated by the ubiquitin‐proteasome system drives progression ...
Wanqiong Li, Xi Xiao, Lingbin Qi, Chanyi Li, Sirui Song, Jiaying Qin, Zhigang Xue, Jinfeng Xue, Huaifang Li   +8 more
wiley   +1 more source

HIV‐1 establishes immediate latency in T cells expressing the viral Nef protein

FEBS Open Bio, EarlyView.
Nef is a viral protein often omitted from HIV‐1 reporter viruses. Consequently, its role in viral latency is unclear. We developed three novel dual reporter HIV‐1 derivatives that express Nef and allow for detection of latent and productive infection. Using these reporters, we show that Nef does not affect the establishment of immediate viral latency ...
Cindy Lam, Ivan Sadowski
wiley   +1 more source

Rapid computation of far-field statistics for random obstacle scattering [PDF]

, 2018
In this article, we consider the numerical approximation of far-field statistics for acoustic scattering problems in the case of random obstacles. In particular, we consider the computation of the expected far-field pattern and the expected scattered ...
Harbrecht, Helmut, Ilić, Nikola, Multerer, Michael D.   +2 more
core   +1 more source

A Corona Australis cloud filament seen in NIR scattered light II: Comparison with sub-millimeter data

, 2009
We study a northern part of the Corona Australis molecular cloud that consists of a filament and a dense sub-millimetre core inside the filament. Our aim is to measure dust temperature and sub-mm emissivity within the region.
Bernard, Bohlin, Boudet, Boulanger, Cambrésy, Cardelli, Carmona, Crapsi, del Burgo, Draine, Dupac, Harju, Joy, Juvela, Juvela, Juvela, Juvela, Juvela, Kramer, Krugel, Lehtinen, Lehtinen, Lehtinen, Lombardi, Lombardi, M. Juvela, Mennella, Nakajima, Nakajima, Nutter, Nutter, Ossenkopf, Padoan, Padoan, Ridderstad, S. Porceddu, Schlegel, Stamatellos, Stepnik, V.-M. Pelkonen   +39 more
core   +1 more source

Nuclear pore links Fob1‐dependent rDNA damage relocation to lifespan control

FEBS Open Bio, EarlyView.
Damaged rDNA accumulates at a specific perinuclear interface that couples nucleolar escape with nuclear envelope association. Nuclear pores at this site help inhibit Fob1‐induced rDNA instability. This spatial organization of damage handling supports a functional link between nuclear architecture, rDNA stability, and replicative lifespan in yeast.
Yamato Okada, Mina Iwaki, Kyosuke Hagiri, Rei Izumi, Masahiko Harata, Chihiro Horigome   +5 more
wiley   +1 more source

Big Geo Data Surface Approximation using Radial Basis Functions: A Comparative Study

, 2017
Approximation of scattered data is often a task in many engineering problems. The Radial Basis Function (RBF) approximation is appropriate for big scattered datasets in $n-$dimensional space.
Majdisova, Zuzana, Skala, Vaclav
core   +1 more source