Results 81 to 90 of about 8,968,637 (317)

Crucial parameters for precise copy number variation detection in formalin‐fixed paraffin‐embedded solid cancer samples

open access: yesMolecular Oncology, EarlyView.
This study shows that copy number variations (CNVs) can be reliably detected in formalin‐fixed paraffin‐embedded (FFPE) solid cancer samples using ultra‐low‐pass whole‐genome sequencing, provided that key (pre)‐analytical parameters are optimized.
Hanne Goris   +10 more
wiley   +1 more source

APPLICATION OF FLOW GRAPHS IN THE MICROWAVE MEASUREMENTS SYSTEMS

open access: yesInformatyka, Automatyka, Pomiary w Gospodarce i Ochronie Środowiska, 2016
Flow graphs are the effective tool for description of the complicated microwave measurement systems and usually are used in the process of creating measurement equation. The algorithm which can find this equation is known as the Mason's gain formula (MGF)
Przemysław Piróg
doaj   +1 more source

Cylindrical cloaking at oblique incidence with optimized finite multilayer parameters

open access: yes, 2010
We propose multilayer cylindrical invisibility cloaks that are optimized for oblique incidences through combination of analytic formalism of scattering and genetic optimization.
Bae-Ian Wu   +15 more
core   +1 more source

TRAIL‐PEG‐Apt‐PLGA nanosystem as an aptamer‐targeted drug delivery system potential for triple‐negative breast cancer therapy using in vivo mouse model

open access: yesMolecular Oncology, EarlyView.
Aptamers are used both therapeutically and as targeting agents in cancer treatment. We developed an aptamer‐targeted PLGA–TRAIL nanosystem that exhibited superior therapeutic efficacy in NOD/SCID breast cancer models. This nanosystem represents a novel biotechnological drug candidate for suppressing resistance development in breast cancer.
Gulen Melike Demirbolat   +8 more
wiley   +1 more source

Nonlocal chiral quark models with wavefunction renormalization: Sigma properties and {pi}-{pi} scattering parameters [PDF]

open access: yes, 2008
We analyze the sigma meson mass and width together with the pion-pion scattering parameters in the context of nonlocal chiral quark models with wave function renormalization (WFR).
S. Noguera, N. Scoccola
semanticscholar   +1 more source

RIPK4 function interferes with melanoma cell adhesion and metastasis

open access: yesMolecular Oncology, EarlyView.
RIPK4 promotes melanoma growth and spread. RIPK4 levels increase as skin lesions progress to melanoma. CRISPR/Cas9‐mediated deletion of RIPK4 causes melanoma cells to form less compact spheroids, reduces their migratory and invasive abilities and limits tumour growth and dissemination in mouse models.
Norbert Wronski   +9 more
wiley   +1 more source

Microwave scattering from ice crystals: how much parameters can differ from equal volume spheres [PDF]

open access: yesAdvances in Geosciences, 2010
The scattering properties of ice crystals at centimeter and millimeter wavelengths are fundamental for their measurement with radars or radiometers as well as for many other applications in remote sensing.
F. Teschl, W. L. Randeu, R. Teschl
doaj   +1 more source

Addressing the challenges of modeling the scattering from bottlebrush polymers in solution [PDF]

open access: yes, 2020
Small‐angle scattering measurements of complex macromolecules in solution are used to establish relationships between chemical structure and conformational properties.
Burns, Adam B.   +4 more
core  

Engineering tandem VHHs to target different epitopes to enhance antibody‐dependent cell‐mediated cytotoxicity

open access: yesFEBS Open Bio, EarlyView.
Tandem VHH targeting distinct EGFR epitopes were engineered into a monovalent bispecific antibody (7D12‐EGA1‐Fc) with more potent ADCC without increasing affinity to EGFR. Structural modeling of 7D12‐EGA1‐Fc showed cross‐linking of separate EGFR domains to enhance CD16a engagement on NK cells.
Yuqiang Xu   +5 more
wiley   +1 more source

Enzymatic degradation of biopolymers in amorphous and molten states: mechanisms and applications

open access: yesFEBS Open Bio, EarlyView.
This review explains how polymer morphology and thermal state shape enzymatic degradation pathways, comparing amorphous and molten biopolymer structures. By integrating structure–reactivity principles with insights from thermodynamics and enzyme engineering, it highlights mechanisms that enable efficient polymer breakdown.
Anđela Pustak, Aleksandra Maršavelski
wiley   +1 more source

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