Results 201 to 210 of about 862,152 (305)

Hydrogel‐Based Smart Materials for Wound Healing and Sensing

Aggregate, EarlyView.
The graphical abstract illustrates the role of hydrogel‐based flexible materials in advancing biomedical applications, including wound healing, point‐of‐care diagnostics, smart patches, and wearable devices. Hydrogels are particularly promising in modern wound care due to their high‐water content, flexibility, and biocompatibility.
Thi Kim Ngan Duong, Thi Thuy Truong, Thi Nhat Linh Phan, Thi Xuan Nguyen, Vu Hoang Minh Doan, Truong Tien Vo, Jaeyeop Choi, Umapada Pal, Prodyut Dhar, Byeongil Lee, Junghwan Oh, Sudip Mondal   +11 more
wiley   +1 more source

Kinetic Redox Shotgun Proteomics Reveals Specific Lipopolysaccharide Effects on Intestinal Epithelial Cells, Mitigated by a Mn Superoxide Dismutase Mimic

Angewandte Chemie, EarlyView.
Proteomics and redoxomics are efficient to quantify the effects of bacterial lipopolysaccharide in intestinal epithelial cells (HT29) at the proteome and at the Cys‐redoxome levels. Oxidative stress is the initial trigger of LPS leading to inflammation.
Martha Zoumpoulaki, Giovanni Chiappetta, Jean Bouvet, Namita‐Raju John, Gabrielle Schanne, Pauline Gehan, Samuel Diebolt, Shakir Shakir, Elodie Quévrain, Emilie Mathieu, Sylvie Demignot, Philippe Seksik, Nicolas Delsuc, Joelle Vinh, Clotilde Policar   +14 more
wiley   +2 more sources

The tau isoform 1N4R confers vulnerability of MAPT knockout human iPSC‐derived neurons to amyloid beta and phosphorylated tau‐induced neuronal dysfunction

Alzheimer's &Dementia, EarlyView.
Abstract INTRODUCTION Human tau protein, composed of six brain‐specific isoforms, is a major driver of Alzheimer's disease (AD). The role of its isoforms however remains unclear and human AD models are scarce. METHODS We generated human MAPT– (tau–) knockout (KO) induced pluripotent stem cells (iPSC) using CRISPR/Cas9, differentiated these into ...
Sarah Buchholz, Mohamed Aghyad Al Kabbani, Michael Bell‐Simons, Lena Kluge, Cagla Cagmak, Jennifer Klimek, Natja Haag, Lukas C. Iohan, Audrey Coulon, Marcos R. Costa, Devrim Kilinc, Hans Zempel   +11 more
wiley   +1 more source

EFFECT OF ATORVASTATIN ON SCAVENGER RECEPTOR CLASS B TYPE I EXPRESSION IN THE LIVER OF GOLDEN HAMSTER WITH DIABETES [PDF]

, 2012
Ling Li, Yan Xu, Lianfeng Chen, Quan Fang, Xiaowei Yan   +4 more
openalex   +1 more source

A Sequential Release Micro‐nano System for Colitis Therapy via Gut Microbiota and Immune Regulation

Angewandte Chemie, EarlyView.
The micro‐nano system achieves the sequential release of drugs in response to gut microbiota and reactive oxygen species (ROS). Inulin prebiotics restore gut microbiota balance. Selenium compounds scavenge ROS and promote macrophage polarization, while 3‐oxolithocholic acid suppresses TH17‐cell differentiation. As a multifactorial therapeutic approach,
Dongdong Zhu, Xiaocao Ma, Jingguo Wang, Tiantian Chen, Jiahui Yang, Yan Liu, Zhun Lin, Minhao Wu, Tony Y. Hu, Yuanqing Zhang   +9 more
wiley   +2 more sources

Impact of genetic variants in human scavenger receptor class B type I (SCARB1) on plasma lipid traits. [PDF]

Circ Cardiovasc Genet, 2014
Niemsiri V, Wang X, Pirim D, Radwan ZH, Hokanson JE, Hamman RF, Barmada MM, Demirci FY, Kamboh MI.   +8 more
europepmc   +1 more source

Targeting signaling pathways in neurodegenerative diseases: Quercetin's cellular and molecular mechanisms for neuroprotection

Animal Models and Experimental Medicine, EarlyView.
Quercetin regulates signaling pathways in neurodegenerative diseases, including NF‐κB, sirtuins, and PI3K/Akt. Studies show quercetin improves symptoms and pathology in neurodegenerative models. The study aims to incorporate laboratory research into practical medical treatment, focusing on quercetin's neuroprotective effects and optimal dosage ...
Md. Rezaul Islam, Md. Ibrahim Khalil Al‐Imran, Mehrukh Zehravi, Sherouk Hussein Sweilam, Mohammad Rakib Mortuza, Jeetendra Kumar Gupta, Thukani Sathanantham Shanmugarajan, Kadirvel Devi, Tanuja Tummala, Mohammed Ali Alshehri, Kalirajan Rajagopal, Mohammed Asiri, Irfan Ahmad, Talha Bin Emran   +13 more
wiley   +1 more source

Sugar‐sensing swodkoreceptors and swodkocrine signaling

Animal Models and Experimental Medicine, EarlyView.
Sugar‐sensing swodkoreceptors that trigger swodkocrine signaling. Abstract Sugars are one of the major metabolites and are essential for nucleic acid synthesis and energy production. In addition, sugars can act as signaling molecules. To study sugar signaling at the systemic level, there is an urgent need to systematically identify sugar‐sensing ...
Savani Anbalagan
wiley   +1 more source

Towards Polymer Composite‐Based Transient Electronic Systems

Advanced NanoBiomed Research, EarlyView.
Biodegradable electronic systems are gaining attention for implantable biomedical applications, targeting disease treatment and lifespan extension. This review covers advances in biocompatible, biodegradable polymer composites using synthetic and natural polymers with conductive, semiconductive, and insulating fillers.
Gwan‐Jin Ko, Venkata Ramesh Naganaboina, Emad S. Goda, Ankan Dutta, Huanyu Cheng, Suk‐Won Hwang   +5 more
wiley   +1 more source

Scavenger receptor class B, type I (Scarb1) deficiency promotes osteoblastogenesis but stunts terminal osteocyte differentiation. [PDF]

Physiol Rep, 2014
Martineau C, Kevorkova O, Brissette L, Moreau R.   +3 more
europepmc   +1 more source