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Scavenger receptor class B type I polymorphisms and peripheral arterial disease
Metabolism, 2007Genetic variations of the scavenger receptor class B type I (SR-BI) have been demonstrated to be associated with plasma lipid parameters, anthropomorphic parameters, and coronary artery disease. We determined the frequency of 3 single-nucleotide polymorphisms within the SR-BI gene (SCARB1) in 354 patients with peripheral arterial disease (PAD) and 354 ...
Andreas, Ritsch +13 more
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Upregulation of scavenger receptor class B type I expression by activation of FXR in hepatocyte
Atherosclerosis, 2010The farnesoid X receptor (FXR), a member of the nuclear receptor superfamily, has been proposed to play an important role in the pathogenesis of cardiovascular diseases by regulating the metabolism and transport of cholesterol and triglyceride. Scavenger receptor class B type I (SR-BI), a high-density lipoprotein receptor, plays an important role in ...
Yingru Zheng +10 more
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Stabilization of Caveolin-1 by Cellular Cholesterol and Scavenger Receptor Class B Type I
Biochemistry, 2002Caveolae are 50-100 nm plasma membrane invaginations, which function in cell signaling, in transcytosis, and in regulating cellular cholesterol homeostasis. These subcompartments of the plasma membrane are characterized by the presence of caveolin proteins.
Douglas M Lublin +6 more
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Characterization of scavenger receptor class B, type I in Atlantic salmon (Salmo salar L.)
Lipids, 2006AbstractThe scavenger receptor class B, type I (SR‐BI) is an important player in regulation of mammalian lipid homeostasis. We therefore wanted to study this receptor in Atlantic salmon (Salmo salar L.), which requires a diet with particular high lipid content. We have for the first time cloned and characterized SR‐BI from a salmonid fish.
Ellen Johanne Kleveland +5 more
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Rosuvastatin attenuates atherosclerosis in rats via activation of scavenger receptor class B type I
European Journal of Pharmacology, 2014In order to investigate the effect and mechanism of action of rosuvastatin on atherosclerotic lesion in a Wistar rat model, 16 Wistar rats were fed a cholesterol-rich, vitamin D3 overload diet and underwent balloon injury of the aorta. One day prior to injury, half of the rats began rosuvastatin treatment (5mg/kg/d) via oral gavage.
Tingru Sun +7 more
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Scavenger Receptor Class B Type I Modulates Epileptic Seizures and Receptor α2δ-1 Expression
Neurochemical ResearchScavenger receptor class B type I (SR-BI) is abundant in adult mouse and human brains, but its function in the central nervous system (CNS) remains unclear. This study explored the role of SR-BI in epilepsy and its possible underlying mechanism. Expression patterns of SR-BI in the brains of mice with kainic acid (KA)-induced epilepsy were detected ...
Yunyi, Huang +4 more
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Function and regulation of hepatic scavenger receptor class B type I (SR-BI)
International Congress Series, 2004Abstract The scavenger receptor class B type I (SR-BI) was the first functional cell surface high-density lipoprotein (HDL) receptor to be described. SR-BI mediates efficient selective lipid uptake and is highly expressed in the liver. In fact, hepatic SR-BI is critical in regulating plasma HDL cholesterol levels and biliary cholesterol secretion in ...
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Critical care management of chimeric antigen receptor T‐cell therapy recipients
Ca-A Cancer Journal for Clinicians, 2022Alexander Shimabukuro-vornhagen +2 more
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