Results 51 to 60 of about 405,215 (310)

Cyclic azapeptide CD36 ligand attenuates cardiac injury and reduces long‐chain fatty acid accumulation after myocardial ischemia–reperfusion in mice

FEBS Open Bio, EarlyView.
In a murine model of myocardial ischemia and reperfusion (MI/R), the CD36 azapeptide ligand MPE‐298 reduces cardiac injury and transiently lowers left ventricular long‐chain fatty acids (LCFAs) accumulation 3 h after reperfusion, accompanied by a decrease of oxidative stress and inflammation‐associated genes' expression in the heart and adipose tissue.
Jade Gauvin, Naghme Radmannia, David N. Huynh, Liliane Ménard, Caroline Daneault, Maïté Veilleux, Ahsanullah Ahsanullah, André C. Carpentier, William D. Lubell, Matthieu Ruiz, Huy Ong, Sylvie Marleau, Simon‐Pierre Gravel   +12 more
wiley   +1 more source

Insights into the feeding ecology of and threats to Sand Cat Felis margarita Loche, 1858 (Mammalia: Carnivora: Felidae) in the Kyzylkum Desert, Uzbekistan

Journal of Threatened Taxa, 2019
Little is known about the ecology of the Sand Cat Felis margarita throughout its range in the deserts of northern Africa to central Asia.  We present observations of the Sand Cat in the southern Kyzylkum Desert, Uzbekistan, potentially preying upon a ...
Alex Leigh Brighten, Robert John Burnside   +1 more
doaj   +1 more source

Individual Variation in Predatory Behavior, Scavenging and Seasonal Prey Availability as Potential Drivers of Coexistence between Wolves and Bears

Diversity, 2020
Several large carnivore populations are recovering former ranges, and it is important to understand interspecific interactions between overlapping species. In Scandinavia, recent research has reported that brown bear presence influences gray wolf habitat
Andrés Ordiz, Cyril Milleret, Antonio Uzal, Barbara Zimmermann, Petter Wabakken, Camilla Wikenros, Håkan Sand, Jon E Swenson, Jonas Kindberg   +8 more
doaj   +1 more source

UiO‐66 metal–organic frameworks in biomedicine: From structural tunability to bioimaging, photodiagnostics, and photodynamic cancer therapy

FEBS Open Bio, EarlyView.
UiO‐66(Zr) metal–organic frameworks are chemically stable, biocompatible, and highly tunable nanomaterials. Their modular structure enables controlled drug delivery, multimodal bioimaging, and light‐activated photodynamic therapy, supporting integrated diagnostic and therapeutic (theranostic) applications in cancer and biomedical research.
Veronika Huntošová, Grigorii Rakhalskii, Miroslav Almáši   +2 more
wiley   +1 more source

Free-radical-scavenging and antioxidant capacities with special emphasis on enzyme activities and in vitro studies in Caralluma flava N. E. Br.

Biotechnology & Biotechnological Equipment, 2018
Caralluma flava is a perennial, succulent edible plant distributed in the hillsides of the United Arab Emirates. In order to validate its use in the traditional system as an edible and medicinal source, we evaluated the antioxidant and in vitro free ...
Kandhan Karthishwaran, Salem Obaid Saeed Obaid Al Shamisi, Shyam Sreedhara Kurup, Sabitha Sakkir, Abdul Jaleel Cheruth   +4 more
doaj   +1 more source

Impact of fisheries on activity, diet and predatory interactions between yellow-legged and Audouin's gulls breeding at the Chafarinas Islands

Scientia Marina, 2003
Interactions between yellow-legged Larus cachinnans and Audouin´s Larus audouinii gulls and fisheries operating around the Chafarinas Islands, located 4.5 km off the Moroccan Mediterranean coast, are reviewed.
Jacob González-Solís
doaj   +1 more source

A review of experimental design in forensic taphonomy: moving towards forensic realism

Forensic Sciences Research, 2020
Forensic taphonomy as a discipline requires standardization to satisfy Daubert criteria for scientific data to be admissible in court. In response, there has been a shift towards quantification of methodology and estimating the postmortem interval ...
Kelly L. Miles, Devin A. Finaughty, Victoria E. Gibbon   +2 more
doaj   +1 more source

Hydrostatic pressure activates HIF‐1α via β‐catenin to promote stemness in breast cancer cells

FEBS Open Bio, EarlyView.
To mimic the elevated intestinal fluid pressure in breast cancers, we loaded human breast cancer cells (MCF‐7, MDA‐MB‐453, and BT‐474) to 50 mmHg hydrostatic pressure. Hydrostatic pressure exposure upregulated HIF‐1α and induced stemness in MCF‐7 and BT‐474 cells.
Da Zhai, Yong Xu, Jingjing Ma, Ratchanee Duangrat, Chen Yan, Jingyan Liang, Hua Wei, Bin Jiang, Tao‐Sheng Li   +8 more
wiley   +1 more source

Seminal cadmium affects human sperm motility through stable binding to the cell membrane

Frontiers in Cell and Developmental Biology, 2023
Environmental pollutants are claimed to be major factors involved in the progressive decline of the fertility rate worldwide. Exposure to the heavy metal Cadmium (Cd) has been associated with reproductive toxicity due to its ionic mimicry.
Claudia Pappalardo, Ilaria Cosci, Giulia Moro, Angela Maria Stortini, Annalisa Sandon, Cristina De Angelis, Giacomo Galdiero, Marco Trifuoggi, Rosario Pivonello, Rosario Pivonello, Federica Pedrucci, Andrea Di Nisio, Carlo Foresta, Alberto Ferlin, Luca De Toni   +14 more
doaj   +1 more source

Dose‐dependent hepatotoxicity of hydrogen peroxide in HepG2 cells and its modulation by CYP450 induction

FEBS Open Bio, EarlyView.
NMR metabolomics revealed concentration‐dependent metabolic perturbations in HepG2 cells exposed to H2O2. Rifampicin pretreatment enhanced metabolic competence, attenuated toxin‐induced alterations and produced metabolite profiles more consistent with human liver physiology, supporting the use of CYP450‐induced HepG2 models for improved in vitro ...
Maren Jinks, Garth L. Maker, Emily C. Davies, Berin A. Boughton, Samantha Lodge   +4 more
wiley   +1 more source