Results 71 to 80 of about 12,028 (205)

Genetic and phenotypic diversity of methicillin-resistant Staphylococcus aureus among Japanese inpatients in the early 1980s

open access: yesScientific Reports, 2021
To trace the linkage between Japanese healthcare-associated methicillin-resistant Staphylococcus aureus (HA-MRSA) strains in the early 1980s and the 2000s onward, we performed molecular characterizations using mainly whole-genome sequencing.
Hui Zuo   +4 more
doaj   +1 more source

Evolution and diversity of community-associated methicillin-resistant Staphylococcus aureus in a geographical region [PDF]

open access: yes, 2011
Background: Community-associated methicillin-resistant Staphylococcus aureus (CA-MRSA) was first reported in remote regions of Western Australia and is now the predominant MRSA isolated in the state.
Geoffrey W Coombs   +8 more
core   +3 more sources

Quorum Sensing Inhibits Type III‐A CRISPR‐Cas System Activity Through Repressing Positive Regulators SarA and ArcR in Staphylococcus Aureus

open access: yesAdvanced Science, Volume 12, Issue 36, September 25, 2025.
This study proposes a novel model illustrating how quorum sensing (QS) regulates the type III‐A CRISPR‐Cas system in Staphylococcus aureus. The QS regulator AgrA suppresses CRISPR‐Cas activity by downregulating the transcriptional regulators SarA and ArcR.
Yang Li   +6 more
wiley   +1 more source

Association between SCCmec types and antimicrobial resistance in clinical MRSA isolates

open access: yesMicrobes and Infectious Diseases, 2022
Abstract BackgroundMRSA is the causative agent of serious infections. MRSA isolates carry mecA gene which confers resistance to all β-lactams, markedly limiting the therapeutic options. SCCmec typing enables strain-based MRSA identification.
Shahinda Rezk   +3 more
openaire   +3 more sources

Staphylococcus aureus as Food-Borne Disease: An Ongoing Threat in Public Health in the Kingdom of Saudi Arabia

open access: yesJournal of Pure and Applied Microbiology, 2023
Majority of the global population have been affected by food-borne diseases, and Staphylococcus aureus is one of the causes of this disease. S. aureus can be transmitted through contaminated food and is a risk to universal human health because of its ...
Mashael Alghizzi, Ashwag Shami
doaj   +1 more source

Ontological representation of CDC Active Bacterial Core Surveillance Case Reports [PDF]

open access: yes, 2014
The Center for Disease Control and Prevention’s Active Bacterial Core Surveillance (CDC ABCs) Program is a collaborative effort betweeen the CDC, state health departments, laboratories, and universities to track invasive bacterial pathogens of particular
Cowell, Lindsay G.   +2 more
core  

Staphylococcal cassette chromosome mec typing and meca sequencing in methicillin-resistant staphylococci from Algeria: A highly diversified element with new mutations in mecA [PDF]

open access: yes, 2016
Genetic mechanisms of methicillin resistance are still relevant in staphylococci. The aims of this study are to assess the possible exchanges of staphylococcal cassette chromosome mec (SCCmec) among isolates of methicillin-resistant staphylococci (MRS ...
Aleo, A.   +5 more
core   +1 more source

Staphylococcus aureus COL: An Atypical Model Strain of MRSA That Exhibits Slow Growth and Antibiotic Tolerance due to a Mutation in PRPP Synthetase

open access: yesMolecular Microbiology, Volume 124, Issue 3, Page 189-203, September 2025.
COL is an unusual “model” strain of Staphylococcus aureus that exhibits slow growth and multidrug antibiotic tolerance. This phenotype is primarily due to a mutation in Prs, which synthesizes the core metabolite phosphoribosyl pyrophosphate (PRPP). Introduction of the COL Prs allele into the antibiotic‐susceptible strain Newman confers tolerance, while
Claire E. Stevens   +5 more
wiley   +1 more source

Phenotypic and Genotypic Characteristics of Methicillin-Resistant Staphylococcus aureus (MRSA) Related to Persistent Endovascular Infection. [PDF]

open access: yes, 2019
Persistent methicillin-resistant Staphylococcus aureus (MRSA) bacteremia (PB) represents an important subset of S. aureus infection and correlates with poor clinical outcomes.
Bayer, Arnold S   +3 more
core   +1 more source

Antibiotic resistance in the environment, with particular reference to MRSA [PDF]

open access: yes, 2008
The introduction of β-lactam antibiotics (penicillins and cephalosporins) in the 1940s and 1950s probably represents the most dramatic event in the battle against infection in human medicine.
Aarestrup   +171 more
core   +1 more source

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