Results 131 to 140 of about 34,826 (273)

Geriatric Nutritional Risk Index Predicts Treatment Intolerance and Survival in Head and Neck Cancer

Head &Neck, EarlyView.
ABSTRACT Background Malnutrition is associated with worse outcomes in head and neck cancer (HNC). The geriatric nutritional risk index (GNRI) may predict postoperative morbidity and survival, but its role remains underexplored. Methods An ambispective study of patients undergoing HNC surgery at two academic centers (2015–2024) was performed ...
Raisa Chowdhury, Alex M. Mlynarek, Keith Richardson, Nader Sadeghi, Michael P. Hier, Sabrina Wurzba, Khashayar Esfahani, Nathaniel Bouganim, Khalil Sultanem, George Shenouda, Christina Tsien, Marco A. Mascarella   +11 more
wiley   +1 more source

Risk of Occult Contralateral Neck Metastasis in Early‐Stage HPV‐Related Lateralized Cancer of the Base of the Tongue

Head &Neck, EarlyView.
ABSTRACT Objectives (1) To determine the incidence of occult contralateral cervical lymph node metastasis in patients with early‐stage HPV‐associated base‐of‐tongue (BOT) oropharyngeal squamous cell carcinoma (OPSCC) treated with primary surgery; and (2) to compare survival and recurrence in patients who did and did not undergo contralateral neck ...
Tyler R. Halle, Austin C. Cao, Anusha G. Naik, Gregory S. Weinstein, Jake J. Lee, Theodore A. Gobillot, Erin R. Kaye, Robert M. Brody, Devraj Basu, Bert W. O'Malley Jr, D. Gregory Farwell, Steven B. Cannady, Alexander Lin, John Lukens, Michelle Gentile, Jason G. Newman, Ara A. Chalian, Christopher H. Rasskeh, Karthik Rajasekaran   +18 more
wiley   +1 more source

Neutrophil to Lymphocyte and Lymphocyte to Monocyte Ratios Predict Improved Survival and Response to Induction Chemotherapy in Locally Advanced Squamous Cell Carcinoma of the Larynx

Head &Neck, EarlyView.
ABSTRACT Background University of Michigan Cancer Center (UMCC) protocol 9520 treated stage III/IV locally advanced squamous cell carcinoma of the larynx (LASCCL) with cisplatin and 5‐fluorouracil to select for definitive therapy based on response.
Zachary Risch, Emily Bellile, Moneb S. Bughrara, Paul L. Swiecicki, Keith Casper, Kelly Malloy, Norman Hogikyan, Matthew Spector, Andrew Shuman, Chaz Stucken, Steven Chinn, Douglas C. Chepeha, Shruti Jolly, Michelle Mierzwa, Carol Bradford, Avraham Eisbruch, Thomas Carey, Mark Prince, Gregory T. Wolf, Francis P. Worden   +19 more
wiley   +1 more source

Efficacy of Multimodal Work‐Up of Head and Neck Squamous Cell Carcinoma Lymph Node Metastasis of Unknown Primary

Head &Neck, EarlyView.
ABSTRACT Background Head and neck squamous cell carcinoma (HNSCC) often presents with cervical lymph node metastasis, with 1%–4% of cases presenting as cancer of unknown primary (CUP). CUP poses diagnostic and therapeutic challenges and is linked to poorer survival outcomes.
Robin W. Jansen, Roland M. Martens, Obaida Abdulrahman, Laura Peferoen, C. René Leemans, Gerben J. C. Zwezerijnen, Jan‐Jaap Hendrickx, Pim de Graaf   +7 more
wiley   +1 more source

Intraoperative Molecular Imaging Can Detect Large Nerve Perineural Invasion: A Case Report

Head &Neck, EarlyView.
ABSTRACT Background Perineural invasion (PNI) in head and neck squamous cell carcinoma (SCC) results in worse overall survival. Diagnosis requires resection and microscopic evaluation. Methods A 63‐year‐old male with persistent cT4aN0 p16‐positive SCC of the left base of tongue following chemoradiotherapy underwent salvage total glossectomy ...
Carleigh R. Burns, Aviva S. Mattingly, Kim Ely, Andreja Radevic, Nicole Meeks, Sydea Maria Ahmad Zaidi, Brandee Brown, Georgii Vasiukov, Michael Topf, Eben Rosenthal   +9 more
wiley   +1 more source

Explainable human‐in‐the‐loop healthcare image information quality assessment and selection

CAAI Transactions on Intelligence Technology, EarlyView., 2023
Abstract Smart healthcare applications cannot be separated from healthcare data analysis and the interactive interpretability between data and model. A human‐in‐the‐loop active learning approach is introduced to reduce the cost of healthcare data labelling by evaluating the information quality of unlabelled medical data and then screening the high ...
Yang Li, Sezai Ercisli
wiley   +1 more source

Oncological Outcomes of Salvage Oropharyngectomy in Irradiated Neck for Recurrent or Metachronous Squamous Cell Carcinoma

Head &Neck, EarlyView.
ABSTRACT Objective To evaluate oncological outcomes and their predictors following salvage oropharyngectomy. Methods This single‐center retrospective study included patients who underwent a salvage oropharyngectomy in an irradiated neck for recurrent or metachronous oropharyngeal squamous cell carcinoma (OPSCC) between 2014 and 2023.
Jade Saykaly, Sébastien Vergez, Agnès Dupret‐Bories, Anouchka Modesto, Benjamin Vairel, Jérôme Sarini, Aurore Siegfried, Ana Cavillon, Emilien Chabrillac   +8 more
wiley   +1 more source

Sizing and concentration analysis of cfDNA using Biabooster technology: Results from a prospective plasma‐based collection of 77 patients with locally advanced unresectable esophageal cancer

International Journal of Cancer, EarlyView.
What's New? This study introduces a novel approach for detecting locally advanced esophageal carcinoma using cell‐free DNA (cfDNA) analysis through a highly sensitive fragmentome assay. Unlike traditional sequencing‐based methods that are limited by the absence of specific mutations in esophageal tumors, our method offers an alternative by quantifying ...
Anouchka Modesto, Sophie Gibert, Caroline Delmas, David Tougeron, Amaury Paumier, Alexandre Taillez, Samuel Le Sourd, Delphine Argo Leignel, Philippe Ronchin, Ariane Darut Jouve, Véronique Vendrely, Olivier Riou, Jérôme Martin‐Babau, Thomas Leroy, Laurent Quéro, Naïma Hanoun, Pierre Cordelier, Veronica Pezzella, Jean Pierre Delord, Rosine Guimbaud, Elizabeth Moyal, Catherine Seva   +21 more
wiley   +1 more source

Predicting optimal impact interventions in the post‐HPV vaccination world

International Journal of Cancer, EarlyView.
Abstract Prophylactic vaccination is a powerful tool that changes exposure to infections and associated morbidity of preventable diseases. We discuss the impact of pneumococci and human papillomavirus (HPV) vaccination on the population biology of the two micro‐organisms and related public health effects.
Matti Lehtinen, Marc Lipsitch, Ville N. Pimenoff, Karin Sundström, Johannes Berkhof, Iacopo Baussano, Simopekka Vänskä, Joakim Dillner   +7 more
wiley   +1 more source

Race‐specific temporal trends of HPV‐related cancers in South Africa: An analysis of the South African National Cancer Registry, 2011–2022

International Journal of Cancer, EarlyView.
What's New? Racial disparities in trends of human papillomavirus (HPV)–associated cancers in South Africa have received limited attention. Here, the authors examined cancer incidence rates among South Africans, with stratification by race and sex, for different timeframes across 2011–2022.
Adino T. Tsegaye, Sizeka A. Mashele, Jaimie Z. Shing, Judith Mwansa‐Kambafwile, Aimée R. Kreimer, Carole Metekoua, Meredith S. Shiels, Mazvita Muchengeti   +7 more
wiley   +1 more source