Results 71 to 80 of about 34,826 (273)

CHB‐Induced Immune Zonation Chaos Elicited LXRα‐mediated Lipid Metabolism Disorders in Kupffer Cells to Induce Cancer Stem Cell Formation

open access: yesAdvanced Science, EarlyView.
By profiling the spatiotemporal hepatic landscape of CHB mouse models, the originally peri‐portal localized KCs migrated to the peri‐central in a CXCL9‐CXCR3‐dependent manner, facilitating their interaction with HBV+ hepatocytes. The interaction promoted LMD in KCs through ASGR1‐induced LXRα degradation, which, in turn, induced CSC formation via Stat3 ...
Jingqi Shi   +18 more
wiley   +1 more source

Ranking Functions for Vector Addition Systems

open access: yes, 2014
Vector addition systems are an important model in theoretical computer science and have been used for the analysis of systems in a variety of areas. Termination is a crucial property of vector addition systems and has received considerable interest in ...
Anders Sjödin (611183)   +9 more
core   +3 more sources

"Gauging" the Fluid [PDF]

open access: yes, 2002
A consistent framework has been put forward to quantize the isentropic, compressible and inviscid fluid model in the Hamiltonian framework, using the Clebsch parameterization.
  +27 more
core   +1 more source

Single‐Nucleus Multi‐Omics Reveals Hypoxia‐Driven Angiogenic Programs and Their Epigenetic Control in Sinonasal Squamous Cell Carcinoma

open access: yesAdvanced Science, EarlyView.
Single‐nucleus multi‐omics profiling of sinonasal squamous cell carcinoma unveils a hypoxia‐driven angiogenic axis. A specific hypoxic tumor subpopulation orchestrates endothelial tip cell differentiation via epigenetically regulated ADM and VEGFA secretion.
Chaelin You   +12 more
wiley   +1 more source

Subjective cognitive complaints in patients with stress-related exhaustion disorder: a cross sectional study

open access: yesBMC Psychology, 2021
Background Stress-related exhaustion is associated with cognitive impairment as measured by both subjective cognitive complaints (SCCs) and objective cognitive test performance.
Andreas Nelson   +6 more
doaj   +1 more source

Lazy Probabilistic Model Checking without Determinisation [PDF]

open access: yes, 2015
The bottleneck in the quantitative analysis of Markov chains and Markov decision processes against specifications given in LTL or as some form of nondeterministic B\"uchi automata is the inclusion of a determinisation step of the automaton under ...
Hahn, Ernst Moritz   +4 more
core   +2 more sources

pH/ROS‐Responsive Injectable Hydrogel Co‐Loaded with B7‐H3 Blocker and NETs Suppressor Boosts OSCC Synergistic Immunotherapy

open access: yesAdvanced Science, EarlyView.
A pH/ROS‐dual‐responsive injectable hydrogel, formed by dynamic boronic ester and Schiff base crosslinking, co‐delivers enoblituzumab (B7‐H3 blocker) and Cl‐amidine (NETs suppressor). Via localized intratumoral delivery, it synergistically reprograms the immunosuppressive tumor microenvironment, overcomes T cell infiltration barriers, restores ...
Huan Li   +12 more
wiley   +1 more source

Expression of taste receptors in Solitary Chemosensory Cells of rodent airways

open access: yesBMC Pulmonary Medicine, 2011
Background Chemical irritation of airway mucosa elicits a variety of reflex responses such as coughing, apnea, and laryngeal closure. Inhaled irritants can activate either chemosensitive free nerve endings, laryngeal taste buds or solitary chemosensory ...
Sbarbati Andrea   +3 more
doaj   +1 more source

Sex determining region Y-Box 2 (SOX2) is a potential cell-lineage gene highly expressed in the pathogenesis of squamous cell carcinomas of the lung. [PDF]

open access: yesPLoS ONE, 2010
Non-small cell lung cancer (NSCLC) represents the majority (85%) of lung cancers and is comprised mainly of adenocarcinomas and squamous cell carcinomas (SCCs). The sequential pathogenesis of lung adenocarcinomas and SCCs occurs through dissimilar phases
Ping Yuan   +17 more
doaj   +1 more source

Static Output Feedback: On Essential Feasible Information Patterns

open access: yes, 2015
In this paper, for linear time-invariant plants, where a collection of possible inputs and outputs are known a priori, we address the problem of determining the communication between outputs and inputs, i.e., information patterns, such that desired ...
Aguiar, A. Pedro   +4 more
core   +1 more source

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