Results 31 to 40 of about 2,341,182 (257)
Molecular Oncology, EarlyView.We identify USP29 as the only DUB mirroring CA9 expression, a marker of hypoxia and HIF pathway activation associated with PCA aggressiveness. USP29 stabilizes HIF‐1α and HIF‐2α via a noncanonical mechanism that is independent of PHD/pVHL activity yet relies on proteasomal regulation, establishing USP29 as a previously unrecognized regulator of hypoxic
Amelie S Schober +16 more
wiley +1 more source
Life cycle assessment of three scenarios of cahrcoal production in the eastern amazon [PDF]
, 2011 The Amazon forest is well known for its wealth of resources. There is a great abundance of iron ore and wood. This situation has promoted the development of pig iron industries based on charcoal for their thermal processes.
Caldeira-Pires, Armando +2 more
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Meta‐analysis fails to show any correlation between protein abundance and ubiquitination changes
FEBS Open Bio, EarlyView.We analyzed over 50 published proteomics datasets to explore the relationship between protein levels and ubiquitination changes across multiple experimental conditions and biological systems. Although ubiquitination is often associated with protein degradation, our analysis shows that changes in ubiquitination do not globally correlate with changes in ...
Nerea Osinalde +3 more
wiley +1 more source
Group 1: Scenario design and development issues [PDF]
All LOFT scenarios and flight segments should be designed on the basis of a detailed statement of specific objectives. These objectives must state what kind of situation is to be addressed and why.
Sherwin, P.
core +1 more source
Literature review of scenario methods. W.P. 5-W.P. 4 D.3 final (version 1) [PDF]
, 2006 This document is a literature review of scenario methods elaborated in the frame of ADD TRANS project (2005-2009) . Within this project, WP4 is aimed at the assessment of land use change at the farm level and its impacts on the territory and WP5 is aimed
Gibon, Annick (ed.), Simon, C.
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TrafficNet: An Open Naturalistic Driving Scenario Library
, 2017 The enormous efforts spent on collecting naturalistic driving data in the recent years has resulted in an expansion of publicly available traffic datasets, which has the potential to assist the development of the self-driving vehicles.
Guo, Yaohui +2 more
core +1 more source
Digital twins to accelerate target identification and drug development for immune‐mediated disorders
FEBS Open Bio, EarlyView.Digital twins integrate patient‐derived molecular and clinical data into personalised computational models that simulate disease mechanisms. They enable rapid identification and validation of therapeutic targets, prediction of drug responses, and prioritisation of candidate interventions.
Anna Niarakis, Philippe Moingeon
wiley +1 more source
FEBS Open Bio, EarlyView.Bioscience students were asked for their opinions on the value and teaching of skills. 204 responded that teamwork, time management and study skills are necessary to reach University, that scientific writing, research, laboratory and presentation skills are taught effectively during their studies, while other skills are gained inherently through study ...
Janella Borrell, Susan Crennell
wiley +1 more source
INFECTIOUS DISEASE, DEVELOPMENT, AND CLIMATE CHANGE: A SCENARIO ANALYSIS [PDF]
We study the effects of development and climate change on infectious disease in Sub-Saharan Africa. Infant mortality and infectious disease are close related, but there are better data for the former. In an international cross-section, per capita income,
Gary W. Yohe +2 more
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User interface development and software environments : the Chiron-1 system [PDF]
, 1990 User interface development systems for software environments have to cope with the broad, extensible and dynamic character of such environments, must support internal and external integration, and should enable various software development strategies ...
Cameron, Mary +3 more
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