Results 71 to 80 of about 2,341,182 (257)
ABSTRACT Chimeric antigen receptor (CAR) T‐cell therapy has been investigated in neurological diseases, encompassing both central nervous system malignancies and autoimmune disorders, thereby extending its application beyond hematological cancers.
Omar Alqaisi +5 more
wiley +1 more source
Clinical Impact of NOTCH3 Variant Location After First Stroke in CADASIL
ABSTRACT Objective Despite its monogenic origin, Cerebral Autosomal Dominant Arteriopathy with Subcortical Infarcts and Leukoencephalopathy exhibits marked variability in clinical expression and severity. Variants in the NOTCH3 gene, within epidermal growth factor‐like repeat domains 1–6 or 7–34, are known to influence disease onset, but their impact ...
Léa Aguilhon +5 more
wiley +1 more source
INDIVISIBILITY AND DIVISIBILITY IN LAND DEVELOPMENT DECISIONS OVER TIME AND UNDER UNCERTAINTY [PDF]
The quasi-option value (QOV) literature originated by Arrow and Fisher (1974) and by Henry (1974) is largely concerned with the analysis of two-period models of land development.
Batabyal, Amitrajeet A., Yoo, Seung Jick
core +1 more source
Domain Objects and Microservices for Systems Development: a roadmap
This paper discusses a roadmap to investigate Domain Objects being an adequate formalism to capture the peculiarity of microservice architecture, and to support Software development since the early stages.
Bucchiarone, Antonio +4 more
core +1 more source
A Two‐Stage Questionnaire and Actigraphy Screening for iRBD in a Multicenter Retrospective Cohort
ABSTRACT Objective Isolated rapid‐eye‐movement sleep behavior disorder is a prodromal marker of synucleinopathies. However, most cases remain undiagnosed due to the insufficient predictive value of questionnaires and limited access to confirmatory video‐polysomnography. We assessed a two‐stage screening strategy combining a brief questionnaire on rapid‐
Caleb A. Massimi +17 more
wiley +1 more source
ICROFS news 1/2008 - newsletter from ICROFS [PDF]
News from ICROFS: N. Halberg: Welcome to a new international centre; presentation of the internatioanl board. Articles: T. Harttung: Organics as the future norm for sustainability; S.O.
Alrøe, Hugo Fjelsted +3 more
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Objective There is growing interest in evaluating new strategies to delay or prevent posttraumatic osteoarthritis (PTOA) in individuals who have sustained anterior cruciate ligament (ACL) injury. This study sought to determine characteristics of potential treatments that are acceptable to patients with ACL injury. Methods Participants with a history of
Kevin Kennedy +9 more
wiley +1 more source
Principles, Progress and Problems in Inflationary Cosmology [PDF]
Inflationary cosmology has become one of the cornerstones of modern cosmology. Inflation was the first theory within which it was possible to make predictions about the structure of the Universe on large scales, based on causal physics.
Brandenberger, Robert H.
core +1 more source
Objective A patient‐centered approach for chronic disease management, including systemic lupus erythematosus (SLE), aligns treatment with patients’ values and preferences, leading to improved outcomes. This paper summarizes how patient experiences, perspectives, and priorities informed the American College of Rheumatology (ACR) 2024 Lupus Nephritis (LN)
Shivani Garg +20 more
wiley +1 more source
Framework for scenario development in LCA [PDF]
This article is based on the work of the SETAC-Europe LCA Working Group ‘Scenario Development in LCA', which has started its work in April 1998. The goal of the Working Group is to focus on the use of scenarios in Life Cycle Assessment (LCA).
Ekvall, Tomas +10 more
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