Results 31 to 40 of about 3,630,548 (240)

Investigating transcription factor dynamics in health and disease using FRAP

open access: yesFEBS Letters, EarlyView.
FRAP analysis of GFP‐tagged transcription factors reveals how molecular mobility and target engagement change in response to drug treatment. By combining live‐cell imaging, quantitative model fitting, and statistical analysis, this approach uncovers transcription factor dynamics linked to disease mechanisms, providing a powerful framework for ...
Kannan Govindaraj   +3 more
wiley   +1 more source

Scenario generation for electricity-computing collaborative planning based on conditional diffusion model

open access: yesDianzi Jishu Yingyong
In the context of computing-power and photovoltaic (PV) coordination, to address the issue that existing scenario generation methods struggle to capture the coordinated patterns of PV output response to computing load, a two-stage scenario generation ...
Gong Taorong, Liu Yuqing, Cui Can
doaj   +1 more source

Wind Power Scenario Generation Method and Application Based on Spatiotemporal Covariance Function

open access: yesShanghai Jiaotong Daxue xuebao, 2023
Wind power generation is different from traditional power generation in which wind power output is highly stochastic and spatio-temporally dependent.
PENG Xinghao, LI Yanting
doaj   +1 more source

From junk to function — How weak selection in eukaryotes builds new parts and drives genomic complexity

open access: yesFEBS Letters, EarlyView.
How do genomes gain new functional parts? In eukaryotes, which tend to evolve under weak selection, much of the genome is junk. Palazzo and Qiu borrow the logic of Markov chains to show how non‐functional DNA becomes functional through the appearance of intermediate states, which arise due to epistasis, buffering, and biochemical messiness, allowing ...
Alexander F. Palazzo, Yi Qiu
wiley   +1 more source

Scenario methodology: New developments in theory and practise : introduction to the special issue [PDF]

open access: yes, 2013
In the call for papers for this special issue, we outlined how scenario method has been applied in a range of contexts over many years, from the military to a wide range of businesses.
Wright, George   +2 more
core   +2 more sources

Robust Representation of Solar Photovoltaic Variability via Wasserstein Distributional Modeling

open access: yesEnergies
The increasing penetration of solar photovoltaic (PV) systems in modern distribution networks introduces significant variability, uncertainty, and spatiotemporal heterogeneity that challenge conventional data-driven modeling approaches.
Andi Liu   +4 more
doaj   +1 more source

L‐aspartate oxidase provides new insights into fumarate reduction in anaerobic darkness in Synechocystis sp. PCC6803

open access: yesFEBS Letters, EarlyView.
Synechocystis strains deficient in succinate dehydrogenase (SDH) secrete more succinate than the WT under dark anaerobic conditions, supporting that SDH then primarily acts as SDH, not as a fumarate reductase. L‐aspartate oxidase (Laspo) from Synechocystis is functional under anaerobic conditions, reducing fumarate to succinate.
Kateryna Kukil   +3 more
wiley   +1 more source

Scenario of the organic food market in Europe [PDF]

open access: yes, 2012
Scenario analysis is a qualitative tool for strategic policy analysis that enables researchers and policymakers to support decision making, and a systemic analysis of the main determinants of a business or sector.
Raffaele Zanoli   +5 more
core   +1 more source

The heterodimeric amino acid transporters (HAT) of the SLC7/SLC3 family: A structure−function relationships and relevance to human pathology

open access: yesFEBS Letters, EarlyView.
Heterodimeric amino acid transporters consist of SLC7 and SLC3 family proteins arranged in a conserved structural organization. They regulate nutrient transport across cell membranes, supporting essential cellular functions. These transporters also contribute to xenobiotic/drug uptake and distribution.
Mariafrancesca Scalise   +5 more
wiley   +1 more source

Participatory Scenario Generation: Communicating Usability Issues in Product Design through User Involvement in Scenario Generation [PDF]

open access: yes, 2009
Scenarios have proven to be a valuable tool in evaluating and communicating usability issues in consumer product design. Scenarios are explicit descriptions of hypothetical use situations. Realistic scenarios can serve as a valuable frame of reference to
van der Bijl-Brouwer, Mieke   +1 more
core   +3 more sources

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