Results 61 to 70 of about 816,298 (267)

Conventional Methods in Housing Market Analysis: A Review of Literature

Baltic Journal of Real Estate Economics and Construction Management, 2020
Housing market analysis has witnessed considerable changes in recent decades, especially as a result of the complexity of human settlements and the dynamics of property market analytical techniques.
Bello Musa Zango, Sanni Mohammed Lekan, Mohammed Jibrin Katun   +2 more
doaj   +1 more source

Modeling Spatial Charging Demands Related to Electric Vehicles for Power Grid Planning Applications

ISPRS International Journal of Geo-Information, 2020
The electrification of the transport sector together with an increasing share of renewable energies has the potential to reduce CO2 emissions significantly. This transformation requires the rollout of charging infrastructure, which has an impact on power
Philip Gauglitz, Jan Ulffers, Gyde Thomsen, Felix Frischmuth, David Geiger, Alexander Scheidler   +5 more
doaj   +1 more source

USP29‐regulated noncanonical stabilization of the hypoxia‐inducible factor‐α in aggressive prostate cancer

Molecular Oncology, EarlyView.
We identify USP29 as the only DUB mirroring CA9 expression, a marker of hypoxia and HIF pathway activation associated with PCA aggressiveness. USP29 stabilizes HIF‐1α and HIF‐2α via a noncanonical mechanism that is independent of PHD/pVHL activity yet relies on proteasomal regulation, establishing USP29 as a previously unrecognized regulator of hypoxic
Amelie S Schober, Leire Moreno‐Cugnon, Laura Martínez‐Pérez, Amaia Ercilla, Amaia Zabala‐Letona, Adrián Vicente‐Barrueco, Maider Fagoaga‐Eugui, Saioa Garcia‐Longarte, Blanca Calle‐Ciborro, Encarnación Pérez‐Andrés, Onintza Carlevaris, Sara Pozo, Isabel Mendizabal, Ugo Mayor, Arkaitz Carracedo, Violaine Sée, Edurne Berra   +16 more
wiley   +1 more source

The Role of Transdisciplinary Research for Agricultural Climate Change Adaptation Strategies

Agronomy, 2018
While science widely acknowledges the necessity of climate change adaptation (CCA), concrete strategies for CCA by major land-use actor groups at a local level are largely missing.
Markus Schermer, Rike Stotten, Ulrich Strasser, Gertraud Meißl, Thomas Marke, Kristian Förster, Herbert Formayer   +6 more
doaj   +1 more source

Longitudinal genome‐wide aneuploidy measurements in circulating cell‐free DNA to predict lack of benefit from pembrolizumab in patients with metastatic urothelial cancer

Molecular Oncology, EarlyView.
Many patients with urothelial cancer do not benefit from treatment with pembrolizumab, while at risk of severe side effects. Changes in the levels of circulating tumor DNA early during treatment, measured by a simple and affordable assay that can be easily implemented in the clinic, can be used as a prognostic tool to identify these patients.
Youssra Salhi, Stavros Makrodimitris, Sandra van Wilpe, Iris te Paske, Vanja de Weerd, Corine M. Beaufort, Hans M. Westgeest, Jens Voortman, Maureen J. B. Aarts, Maud Rijnders, Astrid A. M. van der Veldt, Ronald de Wit, Niven Mehra, Saskia M. Wilting, Debbie G. J. Robbrecht   +14 more
wiley   +1 more source

In vitro and in silico modelling of ROS1‐positive non‐small cell lung cancer reveals fusion‐dependent tyrosine kinase inhibitor responses

Molecular Oncology, EarlyView.
Drug resistance limits treatment success in a subset of lung cancers driven by ROS1 gene alterations. Using patient‐derived cells and computer simulations, we studied three key mutations and how they affect five targeted drugs. The mutations reduced drug effectiveness in different ways by altering protein structure and behavior.
Farhan Ul Haq, Marc Terrones, Felicia Rodrigues Fortes, Anne Schepers, Alessia Denis, Christophe Deben, Ken Op de Beeck, Guy Van Camp, Geert Vandeweyer   +8 more
wiley   +1 more source

Scenario Analysis

, 2019
The performance of TSO-DSO coordination schemes depends on the characteristics of the electricity systems in which regulation reserves can be provided by both transmission and distribution resources. In order to investigate the main aspects influencing TSO-DSO interactions, three detailed electricity scenarios (related to the expected 2030 evolution of
Rossi, Marco, Merino, Julia, Madina, Carlos, Turienzo, Elena, Svendsen, Harald, Kuusela, Pirkko, Koponen, Pekka   +6 more
openaire   +3 more sources

Pharmacological chromatin remodeling enhances response to estrogen therapy in ER+ breast cancer

Molecular Oncology, EarlyView.
Estrogen therapy elicits clinical benefit in ~ 30% of patients with endocrine‐resistant estrogen receptor (ER)‐positive breast cancer. Based on findings that ER transcriptional activation underlies response to estrogen therapy, we tested the effects of epigenetic dysregulation via pharmacological inhibition of histone deacetylases (HDACi).
Anneka L. Johnson Thomas, Barbara Karakyriakou, Patricia C. Muskus, Alyssa M. Roberts, Justin Rendleman, Alexa Warren, Hanxu Lu, Kimberly A. Birmingham, Malone K. Friedman, Abigail E. Goen, Huijuan Yang, Owen M. Wilkins, Fred W. Kolling, Eugene Demidenko, Julie M. Jorns, Brock C. Christensen, Todd W. Miller   +16 more
wiley   +1 more source

Investigating Integrated Approaches to Elderly Support for Tehrani Family in the Horizon of 1430 [PDF]

پژوهشنامه مددکاری اجتماعی, 2018
One of the important issues facing Tehrani families is the protection of the elderly. Future demographic, family, economic, and cultural changes will add to those more complex dimensions.
jafar hezajaribi, masod alaminesi, aliakbar tajmazenani, javad feli   +3 more
doaj   +1 more source

ISS-Scenario: Scenario-Based Testing in CARLA

The rapidly evolving field of autonomous driving systems (ADSs) is full of promise. However, in order to fulfil these promises, ADSs need to be safe in all circumstances. This paper introduces ISS-Scenario, an autonomous driving testing framework in the paradigm of scenario-based testing.
Renjue Li, Tianhang Qin, Cas Widdershoven   +2 more
openaire   +3 more sources