Results 101 to 110 of about 5,220,122 (327)

LDAcoop: Integrating non‐linear population dynamics into the analysis of clonogenic growth in vitro

open access: yesMolecular Oncology, EarlyView.
Limiting dilution assays (LDAs) quantify clonogenic growth by seeding serial dilutions of cells and scoring wells for colony formation. The fraction of negative wells is plotted against cells seeded and analyzed using the non‐linear modeling of LDAcoop.
Nikko Brix   +13 more
wiley   +1 more source

The Role of Transdisciplinary Research for Agricultural Climate Change Adaptation Strategies

open access: yesAgronomy, 2018
While science widely acknowledges the necessity of climate change adaptation (CCA), concrete strategies for CCA by major land-use actor groups at a local level are largely missing.
Markus Schermer   +6 more
doaj   +1 more source

Conventional Methods in Housing Market Analysis: A Review of Literature

open access: yesBaltic Journal of Real Estate Economics and Construction Management, 2020
Housing market analysis has witnessed considerable changes in recent decades, especially as a result of the complexity of human settlements and the dynamics of property market analytical techniques.
Bello Musa Zango   +2 more
doaj   +1 more source

Modeling Spatial Charging Demands Related to Electric Vehicles for Power Grid Planning Applications

open access: yesISPRS International Journal of Geo-Information, 2020
The electrification of the transport sector together with an increasing share of renewable energies has the potential to reduce CO2 emissions significantly. This transformation requires the rollout of charging infrastructure, which has an impact on power
Philip Gauglitz   +5 more
doaj   +1 more source

Tumour–host interactions in Drosophila: mechanisms in the tumour micro‐ and macroenvironment

open access: yesMolecular Oncology, EarlyView.
This review examines how tumour–host crosstalk takes place at multiple levels of biological organisation, from local cell competition and immune crosstalk to organism‐wide metabolic and physiological collapse. Here, we integrate findings from Drosophila melanogaster studies that reveal conserved mechanisms through which tumours hijack host systems to ...
José Teles‐Reis, Tor Erik Rusten
wiley   +1 more source

Colorectal cancer‐derived FGF19 is a metabolically active serum biomarker that exerts enteroendocrine effects on mouse liver

open access: yesMolecular Oncology, EarlyView.
Meta‐transcriptome analysis identified FGF19 as a peptide enteroendocrine hormone associated with colorectal cancer prognosis. In vivo xenograft models showed release of FGF19 into the blood at levels that correlated with tumor volumes. Tumoral‐FGF19 altered murine liver metabolism through FGFR4, thereby reducing bile acid synthesis and increasing ...
Jordan M. Beardsley   +5 more
wiley   +1 more source

Keratin 19 as a prognostic marker and contributing factor of metastasis and chemoresistance in high‐grade serous ovarian cancer

open access: yesMolecular Oncology, EarlyView.
Keratin 19 (KRT19) is overexpressed in high‐grade serous ovarian cancer with high levels of Kallikrein‐related peptidases (KLK) 4–7 and is associated with poor survival. In vivo analyses demonstrate that elevated KRT19 increases peritoneal tumour burden.
Sophia Bielesch   +13 more
wiley   +1 more source

Mixing Scenarios for Lattice String Breaking

open access: yes, 1998
We present some simple scenarios for string breaking on the lattice based on a crude strong coupling model introduced previously. We review the dependence of the model on lattice spacing and extend it to include degenerate dynamical quarks and also meson
Drummond, I T
core   +1 more source

Targeting TNBC: core–shell polycationic polyurea dendrimers with inherent anticancer activity

open access: yesFEBS Open Bio, EarlyView.
Core–shell polycationic PURE dendrimers were tested in TNBC‐derived tumor models. Both formulations selectively targeted TNBC and effectively reduced tumor volume. PUREG4‐OEI48 suppressed tumor growth without detectable toxicity, whereas PUREG4‐OCEI24, despite showing efficacy, induced hepatic toxicity.
Adriana Cruz   +9 more
wiley   +1 more source

Macroecology meets IPBES

open access: yesFrontiers of Biogeography, 2016
The Intergovernmental Platform for Biodiversity and Ecosystem Services (IPBES), established in 2012 to counter the biodiversity crisis, requires the best scientific input available to function as a successful science-policy interface that addresses the ...
Christian Hof   +10 more
doaj  

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