Results 101 to 110 of about 1,543,904 (315)

Early Clinical, Imaging, and Pathological Characteristics of SRPK3/TTN‐Digenic Myopathy

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective SRPK3/TTN‐digenic myopathy was recently established as a skeletal muscle myopathy caused by digenic inheritance. This study characterizes the early clinical presentation of SRPK3/TTN‐digenic myopathy in one previously reported and seven newly identified pediatric patients.
Rotem Orbach, Sandra Donkervoort, Carola Hedberg‐Oldfors, Giovanni Baranello, Dimah Saade, Precilla D'Souza, Ruchee Patel, Eva Michael, A. Reghan Foley, Diana Bharucha‐Goebel, S. Jin Haugland, Meghan McAnally, Omer Abdul Hamid, Katherine Chao, Ellen F. Macnamara, Alan H. Beggs, Anna Sarkozy, Juliane Mueller, Steven A. Moore, Richard S. Finkel, Cynthia J. Tifft, Francesco Muntoni, Anders Oldfors, Carsten G. Bönnemann   +23 more
wiley   +1 more source

Scenarios and Sustainability A Swedish Case Study of Adaptation Tools for Local Decision-Makers [PDF]

Adaptation to climate change often involves long time frames and uncer-tainties over consequences of chosen adaptation measures. In this study, two tools developed for assisting local decision-makers in adaptation planning were tested: socio-economic ...
Carlsen, Henrik, Baard, Patrik, Vredin Johansson, Maria, Edvardsson Björnberg, Karin   +3 more
core  

Environmental Life Cycle Assessment of Healthcare Waste Valorisation Alternatives

Environmental and Climate Technologies
Infectious healthcare waste (iHCW), after microbial inactivation treatment, primarily ends up in landfills. Although the morphological composition of iHCW depends on the type of health facility, predominantly HCW consists of plastic and textile waste ...
Zlaugotne Beate, Zandberga Anda, Gusca Julija, Kalnins Silvija Nora   +3 more
doaj   +1 more source

Scenario’s evaluation by design. A “scenarios approach” to resilience

TECHNE - Journal of Technology for Architecture and Environment, 2018
This contribution describes opportunities and advantages related to the use of the “scenarios” approach in the design of resilient anthropic systems. A methodology that aims to support, from the early stages of the decision-making process, strategical choices concerning complex works and areas by duration, size and interactions with the environment.
Di Giulio, Roberto, Emanueli, Luca, Lobosco, Gianni   +2 more
openaire   +3 more sources

Remarkable Recovery After Delayed High‐Dose Methylprednisolone in a Rare Case of Penetrating Spinal Cord Injury

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Traumatic spinal cord injury (TSCI) caused by sharp‐force penetration is exceptionally rare, and the use of high‐dose methylprednisolone (MP) remains highly controversial, especially beyond the conventional 8‐h treatment window. This case report describes a 30‐year‐old male with acute incomplete TSCI following a knife stab wound to the right ...
Honghong Wang, Shuang Liu, Jiale Wang, Kaiyang Xue, Shenwei Li, Zhongheng Du   +5 more
wiley   +1 more source

Participatory scenario planning in place-based social-ecological research: insights and experiences from 23 case studies

Ecology and Society, 2015
Participatory scenario planning (PSP) is an increasingly popular tool in place-based environmental research for evaluating alternative futures of social-ecological systems. Although a range of guidelines on PSP methods are available in the scientific and
Elisa Oteros-Rozas, Berta Martín-López, Tim M. Daw, Erin L. Bohensky, James R.A. Butler, Rosemary Hill, Julia Martin-Ortega, Allyson Quinlan, Federica Ravera, Isabel Ruiz-Mallén, Matilda Thyresson, Jayalaxshmi Mistry, Ignacio Palomo, Garry D. Peterson, Tobias Plieninger, Kerry A. Waylen, Dylan M. Beach, Iris C. Bohnet, Maike Hamann, Jan Hanspach, Klaus Hubacek, Sandra Lavorel, Sandra P. Vilardy   +22 more
doaj   +1 more source

CAR T‐Cell Therapy in Neurology: A Scoping Review of Neuro‐Oncology, Autoimmune Diseases & Neurotoxicity

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Chimeric antigen receptor (CAR) T‐cell therapy has been investigated in neurological diseases, encompassing both central nervous system malignancies and autoimmune disorders, thereby extending its application beyond hematological cancers.
Omar Alqaisi, Mohammed Dibas, Patricia Tai, Ala Dibas, Osama Souied, Suhair Al‐Ghabeesh   +5 more
wiley   +1 more source

Clinical Impact of NOTCH3 Variant Location After First Stroke in CADASIL

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Despite its monogenic origin, Cerebral Autosomal Dominant Arteriopathy with Subcortical Infarcts and Leukoencephalopathy exhibits marked variability in clinical expression and severity. Variants in the NOTCH3 gene, within epidermal growth factor‐like repeat domains 1–6 or 7–34, are known to influence disease onset, but their impact ...
Léa Aguilhon, Hugues Chabriat, Dominique Hervé, Stéphanie Guey, Sophie Tezenas Du Montcel, Juliette Ortholand   +5 more
wiley   +1 more source

Design of an Improved Method for Task Scheduling Using Proximal Policy Optimization and Graph Neural Networks

IEEE Access
Modern computational environments have been getting more and more complex and dynamic; hence, mechanisms of task scheduling are increasingly sophisticated in order to guarantee optimal resource usage and reduced latency.
Nemilidinea Anantharami Reddy, B.V. Gokulnath   +1 more
doaj   +1 more source

Dynamic Modeling of Kosovo's Electricity Supply-Demand, Gaseous Emissions and Air Pollution

Journal of Sustainable Development of Energy, Water and Environment Systems, 2015
In this paper is described the developing of an integrated electricity supply–demand, gaseous emission and air pollution model for study of possible baseline electricity developments and available options to mitigate emissions.
Sadik Bekteshi, Skender Kabashi, Skender Ahmetaj, Ivo Šlaus, Aleksander Zidanšek, Kushtrim Podrimqaku, Shkurta Kastrati   +6 more
doaj   +1 more source