Results 41 to 50 of about 1,246,428 (253)
Diversity and complexity in neural organoids
FEBS Letters, EarlyView.Neural organoid research aims to expand genetic diversity on one side and increase tissue complexity on the other. Chimeroids integrate multiple donor genomes within single organoids. Self‐organising multi‐identity organoids, exogenous cell seeding, or enforced assembly of region‐specific organoids contribute to tissue complexity.
Ilaria Chiaradia, Madeline A. Lancaster
wiley +1 more source
Design and analysis strategies for robust microbiome ageing research
FEBS Letters, EarlyView.The gut microbiome changes with age and associates with age‐related morbidity and mortality, establishing it as a potential biomarker and intervention target for ageing. Realising this potential requires methodological rigour, yet distinguishing biological signals from methodological artefacts remains challenging across cohorts. This review provides an
Mark Olenik +5 more
wiley +1 more source
Multimodal and Temporal Graph Fusion Framework for Advanced Phishing Website Detection
IEEE AccessPhishing attacks are among the persistent threats that are dynamically evolving and demand advanced detection mechanisms to counter more sophisticated techniques.
S. Kavya, D. Sumathi
doaj +1 more source
Electronic Notes in Theoretical Computer Science, 2005 AbstractThis paper proposes a merge operator for behavioral requirements expressed by Message Sequence Charts and shows how this product can be systematically used to integrate new behaviors in an existing one. First the merge operator is defined as a fibered product of scenario descriptions. This product is then used to integrate a consensus mechanism
Jacques Klein +2 more
openaire +2 more sources
Parameterized Dataflow Scenarios [PDF]
IEEE Transactions on Computer-Aided Design of Integrated Circuits and Systems, 2015 Although well-suited for capturing concurrency in streaming applications, purely dataflow-based models of computation are lacking in expressing intricate control requirements that many modern streaming applications have. Consequently, a number of modeling approaches combining dataflow and finite-state machines has been proposed.
Mladen Skelin +3 more
openaire +3 more sources
Investigating transcription factor dynamics in health and disease using FRAP
FEBS Letters, EarlyView.FRAP analysis of GFP‐tagged transcription factors reveals how molecular mobility and target engagement change in response to drug treatment. By combining live‐cell imaging, quantitative model fitting, and statistical analysis, this approach uncovers transcription factor dynamics linked to disease mechanisms, providing a powerful framework for ...
Kannan Govindaraj +3 more
wiley +1 more source
EVALUATION OF WORLD ENERGY SCENARIOS
Vestnik MGIMO-Universiteta, 2016 What are the future global systems developments? It remains one the biggest unknown, especially in terms of energy, as it is globally considered as both cause and solution for multiple problems of the humanity. Therefore, nowadays a number of experts are
V. I. Salygin, I. I. Litvinyuk
doaj +1 more source
FEBS Letters, EarlyView.How do genomes gain new functional parts? In eukaryotes, which tend to evolve under weak selection, much of the genome is junk. Palazzo and Qiu borrow the logic of Markov chains to show how non‐functional DNA becomes functional through the appearance of intermediate states, which arise due to epistasis, buffering, and biochemical messiness, allowing ...
Alexander F. Palazzo, Yi Qiu
wiley +1 more source
AgricultureScenario planning is a potentially effective method for supporting long-term planning for sustainable and resilient food systems; however, scenario exercises are often limited by too much focus on a single preferred future, not accounting for uncertainty
Robert Newell +3 more
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FEBS Letters, EarlyView.Synechocystis strains deficient in succinate dehydrogenase (SDH) secrete more succinate than the WT under dark anaerobic conditions, supporting that SDH then primarily acts as SDH, not as a fumarate reductase. L‐aspartate oxidase (Laspo) from Synechocystis is functional under anaerobic conditions, reducing fumarate to succinate.
Kateryna Kukil +3 more
wiley +1 more source